Holiday houses in East Prairie

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Top-rated holiday rentals in East Prairie

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
A red barn with a peaked roof is set against a lush green landscape, reflecting softly in a calm pond nearby. Tall grasses frame the water’s edge, while trees provide a natural backdrop under a partly cloudy sky.
Cabin in Dongola
5 out of 5 average rating, 103 reviews

Charming Cabin Overlooking 5 Acre Lake

This cozy, newly remodeled, and inviting cabin offers you a relaxing, serene, and tranquil setting. During your stay you will see nature at its finest. Enjoy a drink on the large deck overlooking the picturesque landscape as well as the lake. If you enjoy fishing then this stocked lake is the place for you. Feel free to fish on the bank or the dock. This cabin is part of the original homestead that was established in 1855 by Valentine Kimber. Located close to wine trails and interstate 57.

Superhost
Floor-to-ceiling windows frame a serene view of the surrounding trees and sky. A warm, electric fireplace offers an inviting glow, while a cozy sleeping area features a quilted bedspread. A television hangs on the wall, and a small table and chairs are positioned nearby.
Treehouse in Annapolis
4.71 out of 5 average rating, 77 reviews

RIVER and SKY Treehouse -Hot tub-Amazing Views-

The River and Sky cabin offers a unique experience with floor to ceiling windows that brings the outdoors in overlooking the St. Francois River. The small cabin has everything you need for a weekend alone, a romantic getaway, or a relaxing time with friends. Sip your morning coffee overlooking the river. Create a rustic outdoor dining experience by cooking with the electric grill under the covered outdoor kitchen. Immerse yourself in the hot tub as eagles fly overhead, or stargaze at night.

Guest favourite
The spacious living area features a comfortable couch and a coffee table, while a set of three barstools accompanies a sleek dining table. Natural light streams through multiple windows, highlighting the wood flooring and modern kitchen appliances in the background.
Tiny home in Jackson
4.95 out of 5 average rating, 63 reviews

The Cottage, Rusted Route Farms

You won’t forget your time in this romantic, memorable place. The Cottage at Rusted Route Farms is a 1 bedroom beautiful suite on an old 10 acre farm history galore. A picturesque pond is settled next to The Market our onsite Restaurant that will be serving food and drinks to be ready on your arrival or for a certain time that you choose. The over 125 year old barn has been renovated to keep the history alive and is located here on site. This retreat is located right outside Cape Girardeau.

Top Guest favourite
The custom-built treehouse is elevated on stilts, surrounded by greenery. A spacious deck features a railing, offering access to the entrance. Steps lead to the ground below, while large glass doors enhance the connection to nature.
Treehouse in Cape Girardeau
5 out of 5 average rating, 205 reviews

Twisted Sassafras Treehouse

A custom-built treehouse located on 10 acres with a water view that you can take in from the hot tub on the deck! It is nestled high in the trees and is the perfect romantic getaway for two! Feel like you are away from it all without being away from it all! This treehouse is located on a county road just minutes from Cape Girardeau. Enjoy catch and release fishing on site, local wineries, shopping in historic downtown Cape Girardeau, local restaurants, gambling, historical sites & more!

Top Guest favourite
A wooden seating area is set along the riverbank, surrounded by lush green trees. The benches are built-in with a rustic finish, offering a natural aesthetic. The flowing river is visible in the background, contributing to a serene outdoor atmosphere.
Cabin in Williamsville
4.99 out of 5 average rating, 313 reviews

Secluded Cabin on BlackRiver/ Hot tub- NO PETS!

This is our family cabin. Our family farms soybeans, rice, and corn. We are too busy working during spring, summer, and some of fall to enjoy our cabin much. We are wanting to share our beautiful place for others to enjoy. It is located approximately 10 minutes from Poplar Bluff, MO. We live about 30 minutes away, so we can be available if needed. We have satellite TV and wi-fi. Cabin is pretty secluded nestled among the trees with the Black River flowing within 100 feet of the deck.

Top Guest favourite
The treehouse is elevated on wooden stilts, surrounded by lush greenery. A wooden deck with a railing extends from the entrance, creating a welcoming outdoor space. Large windows brighten the upper level, while a sun art piece adorns the side of the structure.
Treehouse in Makanda
4.96 out of 5 average rating, 438 reviews

Panthers Inn Treehouse

Come nestle amongst the leaves at Panthers Inn Treehouse. This secluded, well equipped, elevated cabin has the perfect combination of natural beauty and artful luxury. Isolated yet conveniently located 2 minutes from Blue Sky and Feather Hill wineries, within 5 minutes of Panthers Den hiking trail and the Shawnee Hills canopy tour and only 10 min from I-57 exit 40. Panthers Inn is the perfect starting and ending point to your Shawnee Hills Wine Country vacation!

Superhost
Home in Sikeston
4.54 out of 5 average rating, 13 reviews

The Gathering Place

Entire older home with plenty of character that includes a living room with fireplace, eat- in kitchen, dining room, master bedroom with king bed/ bathroom with small shower, and 2nd bedroom with queen bed and futon, full bathroom with tub and shower enclosure on the main level. Lower level has 3 bedrooms- 2 king beds and 1 queen, 1 bathroom with a garden tub, laundry room, and sitting area. Spacious enough for families, groups, or extended stays.

Guest favourite
The exterior of a newly renovated home is showcased, featuring a brown brick façade, a welcoming front porch with seating, and decorative flower pots. A well-kept lawn leads to a gravel driveway that provides access to the entrance.
Home in Sikeston
4.97 out of 5 average rating, 29 reviews

Newly Renovated 3 Bedroom 2 Bath Home - Sleeps 9

Looking for a spacious and welcoming Airbnb in Sikeston? 🏡✨ This gorgeous, newly renovated 3 bedroom, 2 bathroom home is the ideal destination for unforgettable memories with your loved ones. The house sleeps up to 9 guests comfortably, making it perfect for families and groups. Conveniently located in a fantastic residential area, you're just moments away from local attractions, shopping, and dining spots.

Guest favourite
Home in New Madrid
4.92 out of 5 average rating, 12 reviews

Family Home near the MS River with a toy Room

The whole group will enjoy easy access to everything from this centrally located place. 3 blocks from the New Madrid boat ramp / levee. Less than 5 miles from HWY 55. Large family style home - on the first level - living room, dining room, kitchen, laundry room, guest bathroom, main bedroom and main bathroom. The upstairs has 2 bedrooms and a toy room with another full bathroom upstairs.

Top Guest favourite
Home in Clinton
4.99 out of 5 average rating, 203 reviews

The Peery House at Springhill Farms

The Peery House is our family home-place, built circa 1900, transformed into a quaint Airbnb. It is located on our farm, Springhill Family Farms in Western KY and is a great place for someone looking to get away from the busyness of life, looking for rest and relaxation or just looking for a unique, little farmhouse while passing through the area.

Top Guest favourite
Home in Hornbeak
4.99 out of 5 average rating, 152 reviews

THE DREAMCATCHER

Beautiful brick home with lake view and access to Reelfoot Lake (no ramp), paved drive with ample parking for boat / trailer, back deck with table and chairs, open space kitchen and den, perfect for group fishing trip, hunting trip, or just sight seeing, (area known for its large population of eagles), quiet neighborhood, peaceful place to stay.

Top Guest favourite
A comfortable living area features a dark sofa adorned with a seasonal pillow. A round chandelier hangs above, providing soft lighting. A coffee table rests in front of the couch, surrounded by side tables with lamps. Wall art depicting winter scenes is displayed above the sofa.
Cottage in Paducah
4.99 out of 5 average rating, 700 reviews

Copper Creek Cottage in the country close to city

Welcome to Copper Creek Cottage. We are located in the country but minutes away from downtown Paducah, and the mall area. We are 2.5 miles from I-24. Our cottage sleeps 4. (Queen bed & full pull-out sofa). The cottage is great for a couple's weekend, girls' trip or any occasion. The nightly price will be reduced for longer stays.

Popular amenities for East Prairie holiday rentals