Guesthouse holiday rentals in Gainesville

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Gainesville guesthouses

Family-Friendly guesthouses

Guest favourite
Guesthouse in Lake City
4.88 out of 5 average rating, 1,072 reviews

Studio loft/ kitchenette/porch/bath

CrystalRating, 5 stars4 days ago
My good friend, her 5 month old and I had a wonderful stay, we cooked dinner on the fire pit and breakfast on the outdoor grill. We took long baths and had deep peaceful sleep. It felt like staying in a treehouse and was perfectly magical
Superhost
Private room in Alachua
4.92 out of 5 average rating, 36 reviews

King room at Pareners Branch Creek Guesthouse

SonjaRating, 5 stars11 months ago
This place was a perfect getaway for us. The pool area is amazing and so relaxing. My family enjoyed the pickleball and basketball. The beds were so comfortable and the room was very clean. Jane greeted us and was very friendly and accommodating. We would love to visit again.
Guest favourite
Guesthouse in Gainesville
4.88 out of 5 average rating, 217 reviews

Sunflower Acres Cottage

TammyRating, 5 stars1 week ago
The place was exactly as advertised. Very cozy, clean, and easy to find. I loved the mint and roses right outside the front door. I will be booking again. Thank you Lorrie
Top Guest favourite
Guesthouse in Gainesville
4.97 out of 5 average rating, 558 reviews

Renovated Private Studio - Walking Distance to UF

AngelaRating, 5 stars1 week ago
PEACEFUL, EVERYTHING SO PRISTINE AND VERY COMFORTABLE! HOST IS REALLY PROACTIVE AND NICE. I RECOMMEND THIS PLACE!
Top Guest favourite
Guesthouse in Gainesville
4.99 out of 5 average rating, 212 reviews

Beautiful Cottage 10 Minute Walk from UF & Stadium

RogerRating, 5 stars1 month ago
We were in town for a UF graduation and the place was perfect. It was an easy 10 minute walk to the stadium. The place is a bit tricky to find but Rich gave use the exact address to use for the GPS and that seemed to work fine.
Guest favourite
Guesthouse in Fort McCoy
4.88 out of 5 average rating, 284 reviews

Blueberry Farm Country Cottage

SarahRating, 5 stars3 weeks ago
My husband and I had a great 3 night stay. We wanted something away from the main city and we got it! The cottage had everything we needed and the host was very responsive when we had questions. Their dog was the absolute sweetest and we were greeted by the cat as soon as we arrived. We pulled fresh eggs from the chicken coop and had a lovely fire the last night. We left feeling rejuvenated!
Top Guest favourite
Guesthouse in Micanopy
4.92 out of 5 average rating, 173 reviews

Private bed and bath above detached garage.

Sherrie & MauriceRating, 5 stars3 weeks ago
Cute place in a beautiful setting. Great communication - proactively provided details on location and made it simple to find.

Guesthouses with a patio

Top Guest favourite
Guesthouse in Reddick
5 out of 5 average rating, 9 reviews

Papy's Place - Horse Farm Retreat

StephenRating, 5 stars1 month ago
Dawns place was a fantastic place to stay. When you arrive you're greeted by the most adorable shepherd who will instantly become your best friend. The house was super well maintained, dawn was an awesome host, and the property is super peaceful. I would definitely book here again in the future and would seriously recommend it for others going forward.
Top Guest favourite
Guesthouse in Gainesville
4.98 out of 5 average rating, 84 reviews

Millhopper Modern near UF&Shands

BrianRating, 5 stars2 weeks ago
A super cozy and quiet studio! It has everything you could need in a place with a great atmosphere to it. Would definitely recommend.
Top Guest favourite
Guesthouse in Williston
4.96 out of 5 average rating, 23 reviews

Hilltop Retreat

TomRating, 5 stars2 weeks ago
Our stay at Hilltop Retreat was incredible. Christina and her brother Ryan were very helpful to us during our entire stay. Christina was very responsive to our questions prior to arrival even though she was on vacation. Hilltop Retreat was very private and quiet. The place was spotless and well appointed. Two smart TVs, large shower and a very comfortable bed all made the stay outstanding. My wife and I would highly recommend Hilltop Retreat. Thank you to both Christina and Ryan.
Superhost
Guesthouse in Gainesville
4.85 out of 5 average rating, 52 reviews

The house of smiles.

CharlotteRating, 5 stars1 week ago
“What a wonderful stay! The space was spotless and filled with charming personal touches that made it feel incredibly warm and welcoming. It was both cozy and private—perfect for a relaxing getaway. Angela was an outstanding host, always responsive and attentive, making sure everything went smoothly from start to finish. Highly recommend!”
Guest favourite
Guesthouse in Fort White
4.98 out of 5 average rating, 82 reviews

Horning’s Guest House -room for 14

AmandaRating, 5 stars4 days ago
Was a perfect place to stop for the night with a big crew, everything was easy to find and lots of amenities offered! Would stay here again!
Superhost
Guesthouse in Gainesville
4.68 out of 5 average rating, 22 reviews

Our Nest Cute House! With pickleball court

KarenRating, 5 stars1 month ago
A great retreat! Excellent location-easy and quick access to UF! I wish I would have known about this place sooner! Love the pickleball court too! I’d stay here again!
Top Guest favourite
Guesthouse in Reddick
5 out of 5 average rating, 124 reviews

Ocala - Reddick Equestrian Studio Apartment.

StephanieRating, 5 stars1 week ago
This is a nice private location. It’s at the end of a gated driveway. There is a small horse stable present as well. It can be hard to find if you are arriving after dark. Some lights on the gate or a light at the end of the driveway would help. I called Phil to help find the location - he was very helpful and friendly, and answered right away. I texted to say I was arriving late due to flights and he already had the A/C on for me. Great little kitchen. Bed was comfortable. Great place to stay! Many thanks to the hosts.
Top Guest favourite
Guesthouse in Gainesville
5 out of 5 average rating, 99 reviews

"Nest" in the Guest House up in the Trees near UF

RichardRating, 5 stars1 month ago
I've been in many Airbnbs all over the world and the Nest might just be my favorite. It's truly a lovely place hosted by a lovely person and I look forward to staying there again!

Guest house rentals with a washing machine and dryer

Guesthouse in High Springs
4.76 out of 5 average rating, 17 reviews

Mother in Law suite/Apartment @ Staycation

ChristyRating, 5 stars2 weeks ago
My husband and I visited the springs and Michael’s apartment was perfect size for just the 2 of us! We got that super late at night and had struggled with finding the correct door entry but other than that it was perfect! Michael was very responsive!
Guest favourite
Guesthouse in Fort White
4.98 out of 5 average rating, 124 reviews

Adorable cozy cabin near North Florida Springs

KiltieRating, 5 stars1 month ago
We had such a wonderful stay at Lisa’s cabin! It was such a relaxing and cozy place to stay after coming home from a long day at the springs. Everything was so clean and Lisa and her husband were so friendly and very responsive. They know the area very well and had lots of great recommendations on what to do. We even got to explore the beautiful neighborhood/community there! I highly recommend if you are looking for a fun and relaxing place to stay :)
Guest favourite
Guesthouse in Gainesville
4.85 out of 5 average rating, 55 reviews

Cedar Guesthouse | Near UF, Stadium, Bat House

KaterinaRating, 5 stars3 weeks ago
Very affordable, private entrance, matches the photos exactly. Perfect little cottage located minutes from UF, the Flying Biscuit Cafe, David’s Pit BBQ, and I-75 to enjoy a 35 min trip to Ichetucknee Springs. 10/10!
Top Guest favourite
Guesthouse in Duckpond
5 out of 5 average rating, 76 reviews

Garden Cottage Sanctuary

RiverRating, 5 stars2 weeks ago
This is THE BEST Airbnb experience I've ever had (and I've stayed in a lot of Airbnbs). The cottage is clean, comfortable, safe, and in an excellent location. I had everything I needed for a month-long stay, and Laura and Naomi made me feel so welcome and right at home. Laura and Naomi are the best Airbnb hosts I've ever had- so thoughtful, considerate; they went above and beyond to make my stay perfect in every way!
Top Guest favourite
Guesthouse in Sugarfoot
5 out of 5 average rating, 19 reviews

Palm N' Pillow • Guesthouse by UF, HCA-FL & Shands

DeborahRating, 5 stars2 weeks ago
Gabriela was very nice and respectful it is nice that she is next door. I enjoyed my stay. I would recommend this place to other people looking for a place to stay.
Top Guest favourite
Guesthouse in Gainesville
4.97 out of 5 average rating, 332 reviews

Lovely Studio Apt, Walk to UF

MatthewRating, 5 stars2 weeks ago
Joanie was an amazing host! The studio was supplied with water bottles, snacks in the fridge, and we were welcomed to some delicious homemade pumpkin bread. It is very peaceful and quiet, we enjoyed our stay!
Guest favourite
Guesthouse in Williston
5 out of 5 average rating, 5 reviews

Amazing farm cottage !

EdanaRating, 5 stars3 weeks ago
We loved staying at Keara and Don’s cute little cottage! Everything was spotless and comfortable. We had everything we needed. Driving down the road through beautiful old oaks covered in Spanish moss takes you back into old florida. My husband and I loved being able to walk right out the door and pet the horses and ponies in the stable. It was very relaxing and peaceful. Perfect spot if you are wanting to go to Devil’s Den or Cedar Lakes Woods and Gardens. It’s literally right around the corner! Keara and Don were very kind, helpful, and responsive. We will definitely stay again if we are ever back in that area!
Top Guest favourite
Guesthouse in Gainesville
4.97 out of 5 average rating, 36 reviews

5 min to downtown 50”tv+streams work desk 1BR/1BA

AngelaRating, 5 stars1 month ago
Mayra was the PERFECT host ! If I could give more than ⭐️⭐️⭐️⭐️⭐️ review I would! This place was the perfect fit if you are needing a peaceful, quiet, relaxing and most importantly private place THIS IS THE ONE ! Everything was exactly as stated and pictured and if I'm being honest the pictures does no justice. I book this place last minute and as soon as I booked Mayra was at my services exquisite customer service

Quick stats about guesthouse rentals in Gainesville

  • Total rentals

    30 properties

  • Nightly prices starting at

    $50 NZD before taxes and fees

  • Total number of reviews

    4.2K reviews

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    30 properties include access to Wi-Fi

  • Popular amenities

    Kitchen, Wi-Fi and Pool

Destinations to explore