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Holiday houses in Isla Iguana, Guna Yala, Panamá

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Top-rated holiday rentals in Isla Iguana, Guna Yala, Panamá

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Boat in San Blas Islands
5 out of 5 average rating, 8 reviews

Private Catamaran live on board

Welcome aboard catamaran Yoyo, your floating home in the San Blas Islands. Your stay includes breakfast and snacks, with an optional meals and drinks package for USD 80 per person per day. For stays of 5 or more days, meals and drinks are included. Spend your days swimming, snorkeling, fishing, exploring hidden beaches, or relaxing on deck, and your nights unwinding under the stars. Experience the perfect blend of adventure, freedom, and laid-back island living with all the comfort you need.

Top Guest favourite
Villa in Panamá
5 out of 5 average rating, 5 reviews

Casa Condal - Your Private Nature Eco-Retreat

Escape the noise, break your routine, and connect with nature at Casa Condal—a modern luxury retreat hidden inside Chagres National Park ✔ WiFi ✔ 65" Smart TV and Sound Bar ✔ Self check-in ✔ Private parking ✔ Fully equipped kitchen ✔ 220mts private trail ✔ Deck-Mirador with FirePit and panoramic view of the mountains and valley ✔ King bed + Full size sofa bed ✔ Wheelchair accessible 40 min from Tocumen Airport. Ideal for Birdwatchers, or a romantic getaway away from the city hectic rhythm.

Guest favourite
A stone pathway leads through lush tropical foliage toward a welcoming entrance. Tall trees and vibrant greenery frame the path, creating a serene approach to the property, which is partially visible in the background, surrounded by nature's tranquility.
Home in Panama City
4.98 out of 5 average rating, 81 reviews

Mountain Retreat

Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Top Guest favourite
A rustic house is nestled among lush greenery, with sturdy stone columns supporting a covered entrance. The surrounding trees provide shade and a sense of privacy, enhancing the tranquil setting. The pathway leading to the door is lined with grass and natural foliage.
Cottage in Panamá
4.89 out of 5 average rating, 57 reviews

Moon House River Dreams Cerro Azul

Fresh and cozy rustic-style country house, located in the high mountains of Cerro Azul. Quiet and private, surrounded by nature and exotic fauna. A river runs through the property with small waterfalls. Ideal for families and couples, groups, retreats, celebrations, up to 5 people. You can breathe peace, tranquility and freshness. Ideal for rest, vacation, remote work or celebration. The stay can be for two nights, weeks, months or a year with a good discount. Pets are welcome for extra fee.

Superhost
An aerial view captures the lush greenery of Narasgandub Island, surrounded by vibrant turquoise waters. The shoreline features a sandy beach bordered by palm trees, creating a tranquil atmosphere. The clear ocean extends into the horizon, highlighting the island's secluded paradise appeal.
Hut in San Blas
4.78 out of 5 average rating, 142 reviews

Bliss in the San Blas Islands

Discover Panama's best-kept secret in San Blas Islands, a set of 365 Caribbean Islands for 365 days of sun. All the Islands are owned by natives, "The Gunas," who will be very keen to welcome you and share their culture. Enjoy our crystal clear water, beautiful sunshine, and white sand, and wake up in the morning to hear the waves of the Ocean and see spectacular scenery from your room. A well-hidden Paradise awaits you in this unforgettable trip that will give you memories for a lifetime.

Guest favourite
A charming stone house is surrounded by lush greenery. The swimming pool is framed by several vibrant blue and yellow chairs, inviting relaxation. Large windows allow natural light to brighten the interior, while flowering plants add a touch of nature.
Cottage in Panamá
4.94 out of 5 average rating, 36 reviews

Cerro Azul, Country House with Heated Pool.

Check-in 9:00 AM Check-out 5:00 PM. Relax with the whole family and friends in this cozy country house. We have a heated pool, a 100-meter covered terrace to celebrate your special occasions (ice machine included), and a person (not mandatory) at your disposal during the day for cleaning and to assist you with everything you need to make your stay pleasant and unforgettable, where tranquility is breathed, among trails, rivers and viewpoints, lots of flora, fauna, 1 hour from the city.

Top Guest favourite
Boat in Guna Yala Comarca
5 out of 5 average rating, 6 reviews

Private Caribbean Boat Retreat, San Blas Islands

Step aboard your own private floating villa in San Blas — no crowds, no shared spaces, just your group and one of the most untouched corners of the Caribbean. This is not a tour. It’s a fully private experience with a dedicated crew, optional chef service, and a completely customizable itinerary designed around you. Wake up surrounded by turquoise waters, explore deserted islands, snorkel vibrant reefs, or simply relax on deck with nothing but the ocean around you.

Guest favourite
The exterior of Villa Lola is highlighted by a welcoming sign and surrounded by lush greenery. A well-maintained outdoor space features a swimming pool beside a relaxing area with white chairs. The two-story structure showcases a charming mix of architecture with a scenic view of the surrounding nature.
Home in Panamá
4.93 out of 5 average rating, 71 reviews

Majestic Villa in the Mountains

Relax with the whole family at this peaceful place to stay. The majestic Villa Lola is a special place located in an exclusive residential area, with 24-hour security, Los Altos de Cerro Azul. A place within Chagres National Park surrounded by rivers, lakes, waterfalls, trails and endless wildlife species, where you can experience a different adventure every day. Located 55 minutes from the city and 30 minutes from Tocumen International Airport :)

Guest favourite
Tiny home in Islas Maqui
5 out of 5 average rating, 5 reviews

Ansubirya Lodge House on Water

Connect with nature on this unforgettable getaway. Come and relax in our water house. Enjoy delicious food prepared by the best chef in San Blas Ibin. Our house has a king-size bed, two hammocks, a table for relaxing on the terrace, and direct access to the water. Paddle our kayak between islands and snorkel on the coral reef. Offer include meals, for two people, 3 meals a day. Come and see it by Yourself.

Superhost
Hut in Mamartupo
4.77 out of 5 average rating, 90 reviews

Ancestral Serenity: Life in an Indigenous Cabin

Welcome to the Guna Yala archipelago, a truly captivating place. The 365 islands that make it up are a haven of biodiversity and rich indigenous culture. If you love nature, diving, or just relaxing to the sound of the waves, Guna Yala is an ideal destination. You can also explore the traditional cabins and taste the local cuisine, which is a reflection of the rich cultural heritage of the region.

Guest favourite
Dome in Panamá
5 out of 5 average rating, 11 reviews

Mountain Dome | Waterfall View | Nature Stay

Inspirado en la fuerza de la montaña, el domo Anmarä ofrece descanso y conexión total con la naturaleza. Cuenta con cama queen y cama full, aire acondicionado, baño privado con agua caliente, mirador con malla, terraza y wifi de fibra óptica. La cocina está totalmente equipada. Disfruta una vista exclusiva hacia la cascada El Vigía y del clima fresco, la paz y la belleza natural de Cerro Azul.

Superhost
The sail yacht Constellation is anchored in tranquil waters, displaying a sleek and modern design. The gentle curves of the hull are highlighted, complemented by the large, covered deck and sails, creating an inviting space for guests to relax and enjoy the surroundings.
Boat in San Blas Islands
5 out of 5 average rating, 5 reviews

Your Own Private Sail Yacht in San Blas

Reserve a private comfortable sail yacht for a special vacation or event. Three private double cabins, saloon double bed, two bathrooms, full kitchen, and spacious cockpit. Island hopping, snorkelling, paddleboards, kayak, and motorized dinghy included.

Popular amenities for Isla Iguana, Guna Yala, Panamá holiday rentals