
Holiday houses in Isthmus of Panama
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Top-rated holiday rentals in Isthmus of Panama
Guests agree: these stays are highly rated for location, cleanliness and more.

Puntita Manzanillo, fantastic sea and jungle
Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.
4.97 out of 5 average rating, 115 reviews
Hot Tub in the Clouds | Luxury Mountain Escape
Looking for the ultimate luxury mountain retreat? Located in one of the highest areas of Altos del María, this stylish and modern home is a feast for the eyes. Relax in the hot tub, unwind in the hammock, and take in lush mountain views surrounded by clouds. Enjoy cool mountain air, tranquility, and complete privacy. Whether you want to simply relax and enjoy the home, or get out and explore, there are plenty of activities and amenities throughout Altos del María to make your stay unforgettable.
5.0 out of 5 average rating, 3 reviews
Beach House-Amazing Pool & Jacuzzi - Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.
4.98 out of 5 average rating, 222 reviews
Costa Blanca Beach & Golf Villa by Decameron
Spacious Villa with Pool, Golf Views & Beach Access Relax in this stylish 4-bedroom villa overlooking the 7th putting green of Mantarraya Golf Course. All on one level, it offers 250 sq m of comfort, with en-suite bathrooms and space for up to 12 guests. Wow ! - Private 15 m pool with shallow area - 15-minute walk to Pacific beach - Access to Owners Beach Club (restaurant + parking) - Peaceful golf course setting Perfect for families, groups, or golf lovers seeking sun and serenity.
4.9 out of 5 average rating, 254 reviews
CasAna
Fantástico lugar con espacios abiertos, luz natural y aire puro, 2 habitaciones con baño interno, terraza para recibir el amanecer y el atardecer, piscina privada que hace sentir que vuelas, mientras puedes compartir con amigos y familiares en un área grupal proporcionada por un espacioso deck, disfrutar de tus asados en la terraza y cocina equipada con todo lo que necesitas Ubicada a 10 mtos de Playa La Ermita y 12 mtos de la entrada del Valle, y a un salto del Restaurante Los Camisones.
4.98 out of 5 average rating, 41 reviews
Casa Coco - Beautiful Mountain Villa With AC
Elegant and modern, our home strikes the perfect balance between luxury and warmth. With ample space to accommodate large groups and families, as well as cozy and inviting for smaller groups. The yard features a covered social area, ideal for relaxing or entertaining. A lush garden adorned with vibrant greenery includes a charming mango tree and mountain peak views. A 5 minute walk to restaurants and the open air market. If you have a group larger than 12- please reach out to us directly.
4.93 out of 5 average rating, 103 reviews
El Palmar, playa a 50 metros
Escucha las olas desde la privacidad de nuestra terraza y crea recuerdos inolvidables en este alojamiento único y familiar a pocos paso de la playa con piscina privada. El palmar es una comunidad tranquila con varios restaurantes disponibles a unos pasos de la casa. La propiedad esta totalmente cercada para la tranquilidad y seguridad de hijos y sus mascotas adicional tienes wifi, TV cable en ambas habitaciones y aires acondicionados en la sala comedor y en todas las recamaras
4.89 out of 5 average rating, 184 reviews
Modern House with Great Views and Heated Pool
Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.
4.82 out of 5 average rating, 337 reviews
Casa Campestre Los Macos, El Valle de Antón
🏡 Bienvenidos a Casa Campestre Los Macos, un refugio acogedor ubicado en el corazón verde de El Valle de Antón, dentro de un cráter volcánico extinto, el más grande habitado en el mundo. Es una experiencia de descanso total, en una zona segura y tranquila, ideal para amantes de la naturaleza, el silencio y el aire puro. Despertarás con el canto de los pájaros, disfrutarás una taza de café en el jardín y pasarás tardes familiares en una casa totalmente equipada.
4.97 out of 5 average rating, 173 reviews
Casa Rosie - Dream Home on Tabogá Island
Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.
4.94 out of 5 average rating, 224 reviews
Mountain retreat
Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.
4.92 out of 5 average rating, 196 reviews
Rustic family mountain home - 5 min walk to town!
Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.
4.96 out of 5 average rating, 201 reviewsPopular amenities for Isthmus of Panama holiday rentals
Other great holiday rentals in Isthmus of Panama

Playa Malibu Beach House.
4.95 out of 5 average rating, 44 reviews
Paradishaus in Natur in Playa Coronado mit Pool
4.94 out of 5 average rating, 35 reviews
Luxury villa with ocean view near Playa Venao
5.0 out of 5 average rating, 13 reviews
Blue Sky Lodge; la mejor vista en Altos del María
4.94 out of 5 average rating, 68 reviews
Luxury Beachfront Home • Private Pool • Coronado
4.89 out of 5 average rating, 18 reviews
Un refugio sereno en el campo
4.95 out of 5 average rating, 61 reviews
Residencia de Vacaciones
4.99 out of 5 average rating, 75 reviews
The Dream of Playa Coronado
5.0 out of 5 average rating, 44 reviews




