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Holiday houses in Isthmus of Panama

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Top-rated holiday rentals in Isthmus of Panama

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Two rustic-style cabins are set along the shoreline, surrounded by lush tropical trees. A wide patio is furnished with colorful chairs, offering views of the water. The natural beauty of the landscape is complemented by the tranquil waves gently lapping at the shore.
Home in La Guaira

Puntita Manzanillo, fantastic sea and jungle

Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

4.97 out of 5 average rating, 115 reviews
Superhost
Home in Altos del María

Hot Tub in the Clouds | Luxury Mountain Escape

Looking for the ultimate luxury mountain retreat? Located in one of the highest areas of Altos del María, this stylish and modern home is a feast for the eyes. Relax in the hot tub, unwind in the hammock, and take in lush mountain views surrounded by clouds. Enjoy cool mountain air, tranquility, and complete privacy. Whether you want to simply relax and enjoy the home, or get out and explore, there are plenty of activities and amenities throughout Altos del María to make your stay unforgettable.

5.0 out of 5 average rating, 3 reviews
Top Guest favourite
Home in Playa Costa Esmeralda

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

4.98 out of 5 average rating, 222 reviews
Top Guest favourite
Apartment in San Carlos District

Casamar | Amplia terraza y jardín vista al mar

Apartamento en primera planta, amplia terraza y jardín privado con vista al mar, diseñado con múltiples espacios para relajarse y compartir. Cada recámara cuenta con su propia terraza, además de varios ambientes exteriores en el jardín. Desde la propiedad se accede directamente a una de las piscinas del complejo y se encuentra a pocos pasos del mar y del club de playa, ideal para disfrutar al máximo la experiencia en Casamar. Complejo con waterpark, piscinas y club de playa con acceso al mar.

4.94 out of 5 average rating, 32 reviews
Guest favourite
A private pool is surrounded by a smooth concrete deck, with gentle steps leading into the water. The adjacent open-air area features large glass doors that highlight the indoor living space, while the softly lit evening sky adds a serene ambiance.
Home in El Higo

CasAna

Fantástico lugar con espacios abiertos, luz natural y aire puro, 2 habitaciones con baño interno, terraza para recibir el amanecer y el atardecer, piscina privada que hace sentir que vuelas, mientras puedes compartir con amigos y familiares en un área grupal proporcionada por un espacioso deck, disfrutar de tus asados en la terraza y cocina equipada con todo lo que necesitas Ubicada a 10 mtos de Playa La Ermita y 12 mtos de la entrada del Valle, y a un salto del Restaurante Los Camisones.

4.98 out of 5 average rating, 41 reviews
Guest favourite
Home in San Carlos District

El Palmar, playa a 50 metros

Escucha las olas desde la privacidad de nuestra terraza y crea recuerdos inolvidables en este alojamiento único y familiar a pocos paso de la playa con piscina privada. El palmar es una comunidad tranquila con varios restaurantes disponibles a unos pasos de la casa. La propiedad esta totalmente cercada para la tranquilidad y seguridad de hijos y sus mascotas adicional tienes wifi, TV cable en ambas habitaciones y aires acondicionados en la sala comedor y en todas las recamaras

4.89 out of 5 average rating, 184 reviews
Guest favourite
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del María

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

4.82 out of 5 average rating, 337 reviews
Superhost
Cabin in Panama City

Casa Club frente al Lago con muelle Jacuzzi y BBQ

Despierta frente al lago en Cerro Azul, donde la naturaleza y el diseño se encuentran en perfecta armonía. Esta casa moderna ofrece 4 habitaciones con baño privado y 2 baños sociales, ideal para celebraciones especiales, bodas íntimas o encuentros inolvidables con familia y amigos. Su cocina abierta estilo industrial se integra con amplios espacios y una terraza que se funde con el paisaje. La suite principal, con jacuzzi, invita a desconectar y reconectar contigo mismo.

5.0 out of 5 average rating, 6 reviews
Top Guest favourite
The modern house is set against a backdrop of rolling mountains, illuminated by the soft glow of evening light. A spacious entrance is visible, with large sliding doors opening to inviting communal areas. Lush greenery surrounds the property, enhancing its natural appeal.
Villa in El Copé

Mountain retreat

Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

4.92 out of 5 average rating, 196 reviews
Top Guest favourite
Apartment in El Chiru

Stunning loft in Buenaventura Golf&Beach Resort

Stunning Remodeled Loft in The Buenaventura Golf & Beach Resort, Panama. Nestled within the lush offerings of Buenaventura Beach Resort in Panama, this completely remodeled loft presents a harmonious blend of modern luxury and natural beauty, creating a truly stunning living space. The loft features an open-concept design that maximizes light and airiness. The high ceilings lend an expansive feel, making the space both inviting and luxurious.

5.0 out of 5 average rating, 45 reviews
Top Guest favourite
A modern beachfront building rises against a bright blue sky, with large windows reflecting the surroundings. Thatched-roof cabanas are visible on the sandy beach, bordered by lush greenery. The structure stands in a tranquil setting, inviting relaxation and enjoying ocean views.
Loft in Rio Hato

Beachfront Loft in Farallón

Wake up to the ocean in this beautiful beachfront loft in Farallón, located in the exclusive Miramar Loft next to the Decameron Hotel. Relax on the balcony with sea views, enjoy the pool, and walk to the beach with private cabanas on the sand. The apartment offers 2 bedrooms, a full kitchen, A/C throughout, and fast Wi-Fi. Just 2 hours from Panama City. Book now and live the beach experience you deserve!

4.98 out of 5 average rating, 87 reviews
Top Guest favourite
A spacious living area is illuminated by natural light streaming through large glass windows. Comfortable seating arrangements are positioned around a circular coffee table, creating an inviting space for relaxation. Scenic mountain views can be seen through the glass, emphasizing the connection with the outdoors.
Cabin in Altos del María

Blue Sky Lodge; la mejor vista en Altos del María

Esta cabaña de lujo en la montaña ofrece un diseño moderno, acabados de calidad y vistas panorámicas de 180° de montañas y mar. Se encuentra en una comunidad cerrada segura, rodeada de un jardín verde, con amplias ventanas de vidrio que favorecen la conexión con la naturaleza. El clima es agradable, con temperaturas entre 23°C y 28°C. .

4.94 out of 5 average rating, 68 reviews

Popular amenities for Isthmus of Panama holiday rentals