House holiday rentals in Jefferson County

Hop off the highway, Relax!

Relax with the whole family at this peaceful place to stay. We are located only 4 miles off of highway 55! There are two bedrooms and two COMFY couches if you have more than 4 staying the night! This is located on a secluded road with two other homes occupied nearby by with quite, but very friendly, residents. This home is 25 minutes away from the historical town of Ste Genevieve, take a look! The host is will be able to assist you almost immediately, whether it be over the app or in person!

Family · Location · Checkout

Pacific Palace, super unique!

The Pacific Palace is unlike any other Airbnb! Located in the heart of downtown Pacific, Missouri - only 2 minutes from Highway 44 and 10 minutes from Purina. This house is an incredible one of a kind treasure with lots of unique features including: outdoor gazebo, fish pond, all original cedar interior design, two second story balconies, two large bat tubs (one located in the main bedroom) and so much more!!! Private parking and a gate for added privacy. Just minutes from Six Flags. Book today

Location · Value · Access

NO PARTIES, VERY QUIET NEIGHBORS. 3 BEDROOM 2 BATH

Two minutes from highways I270, I55, I44 which is within 15 minutes of downtown St. Louis. Busch Stadium, St Louis Blues, Zoo, Aquarium, Forest Park, Wash U, Soulard, Central West End, Missouri Botanical Garden, Anheuser-Busch. Other close attractions- Laumeier Sculpture Park, Children’s Magic House, Museum of Transportation, Grant's Farm. We are within one mile of Mercy South Hospital if you are working or visiting. MO Baptist, Mercy, BJC, Children's hospital all 15 minutes. 20 min/airport.

Location · Family · Laundry

The St. Louie House in Fenton w/deck & large yard!

Enjoy your stay in our St. Louis themed house. The kitchen is fully stocked with coffee bar, dishes, pots & pans. The three bedrooms, the Cardinals room, the Blues room and the Union Station room each have a queen bed with spacious closets. A large covered deck for BBQ. The full basement is set for family fun! A full sized laundry room is there for your convenience. The Arch, Stadium, Six Flags, Science Center, Zoo, Forest Part, etc are under 30 minutes. Local shopping is within minutes.

Location · Value · Kitchen

2BR House with Hot Tub near Washington State Park!

This newly remodeled 2 bedroom house is an ideal choice for guests looking to explore the beauty of Bonne Terre, attend weddings and local events, or visit Fyre Lake Winery, which is only a mile away. You'll find two comfortable bedrooms - one with a king-size bed and the other with a full-size bed - providing a peaceful retreat after a day of adventure. Additionally, Bonne Terre Mines are conveniently located just 16 minutes away, making it a perfect spot to stay while exploring the area.

Location · Value · Air conditioning

Stonehaven Ranch LLC

Stonehaven Ranch is a beautifully renovated historic rock home with rustic charm and modern conveniences. The fully equipped kitchen includes a coffee bar, microwave, dishwasher, stainless steel refrigerator, and gas range with griddle. The 170-acre private ranch offers miles of hiking trails, horses, chickens, and guinea fowl. Located just four miles from I-55, it's near historic Ste. Genevieve and Festus, perfect for dining and wine tasting. After exploring, relax in the jetted tub.

Location · Family · Hospitality

Honeymoon Suite at Camp Skullbone In The Woods

Experience a romantic, quiet, and cozy chalet designed for two! This charming retreat features vintage décor and all the modern amenities you need for a comfortable stay. Unwind indoors by kicking back and watching a movie, surfing the web, curling up with a good book or a friendly board game, or sharing a drink with that special someone. In the evening, relax on the cozy deck under the stars, basking in the warm glow of the gas fire pit or unwinding in the inviting private hot tub!

Family · Location · Skiing

Honey Stop the car‼️

Inviting peaceful & tranquil setting! Master Suite on lower level and Open Concept. You'll LOVE the beautifully updated eat-in kitchen and stainless-steel appliances. Family Friendly atmosphere beautiful views, spacious home with ample living space. Finished basement with bonus area to relax, and a partial bathroom located on the lower level. Short drive away restaurants, shopping and entertainment. Prepare to fall in love with this stunning gem. This home is a MUST SEE!

Family · Location · Accuracy

Peaceful, home in Pacific, Just like Grandma's!

Full kitchen, washer/dryer, wifi, secluded setting just minutes to town. 7 mins to Six Flags 12 mins to Purina Farms 15 min to Hidden Valley Skiing 5 mins to I-44, 5 min. to River access 35 minutes to the downtown ST Louis, Arch, Busch Stadium, City Museum. 20 min. to Magic House, Science Center, Zoo. 25 mins. to Outlet Malls 10 minutes to St Alban Kid friendly! pets welcome-NOT on furniture or beds, please crate if gone. Additional pet fee applies.

Location · Value · Hospitality

Luxury Retreat -Hot Tub, Fire Pit & Private Trails

Goforth Into Nature is a private countryside retreat in southeast Missouri, completed March 2025, designed for a peaceful, secluded getaway. Enjoy a 7-person hot tub, fire pit, and patio under the stars in a quiet natural setting—perfect for a romantic escape or weekend retreat. Inside features a queen pillow-top bed, sleeper sofa, luxury linens, rainfall shower, fully stocked kitchen, washer/dryer, and free Wi-Fi.

Location · Family · Checkout

3 Bedroom Ranch with Deck in a Quiet Neighborhood

• Ranch style w/ 1025 square feet • Subdivision neighborhood w/ grassy common ground areas • Driveway parking for 2 vehicles • Safe neighborhood • 52" TV w/ Roku streaming stick • A baby gate at the top of the steps to the basement laundry room • Deck and backyard • Close to Hwy 55, about a 30 minute drive from Down Town St. Louis. • Near Historic Kimmswick (quaint shops & resturants), and Mastodon State Park

Family · Value · Walkability

Great Location - Quiet & Family-Friendly Home

Enjoy a clean, comfortable, and well-equipped home in a quiet and peaceful neighborhood. Perfect for families, couples, or business travelers, this house offers fast Wi-Fi, a fully stocked kitchen, and easy self-check-in. Close to shopping, dining, and St. Louis attractions like the Gateway Arch, Busch Stadium, Forest Park, and the St. Louis Zoo —everything you need for a smooth and relaxing stay.

Location · Family · Backyard