
Holiday houses in La Mesa District
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Top-rated holiday rentals in La Mesa District
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Beachfront Family EcoParadise to Coiba lsl BunkBed
Experience authentic Panama in our family-owned 30-hectare private tropical beachfront paradise. Accessible only by boat (30-min ride from Pixvae or 1:30hr from Santa Catalina). Gateway to Coiba Island, our remote bay offers pristine jungle, diverse wildlife, and breathtaking views. Enjoy kayaking, fishing, and guided eco-tours. Spot howler monkeys, sloths, and rare birds. Savor fresh tropical fruits and local cuisine. Perfect for nature lovers, photographers, and digital nomads (WiFi available)

North Villa with Rooftop. Full Kitchen!
Fly / Drive - Tour Coiba - Relax at the North Villa! The North Villa has plenty of space. The rooftop patio has furniture, a bar and is perfect for star gazing and birdwatching. Your villa comes with ample bedrooms, fully equipped kitchen (cookware, spices, blender, coffee maker etc), full living area, charcoal grill, covered parking and dedicated Internet. We offer a free ground shuttle if you fly into the local airstrip. Feel free to message us and learn how to skip the 6hr+ drive!

Casa a minutos de Santiago, U Latina, HospChichoF.
Casa amplia, cómoda y totalmente equipada en una ubicación estratégica de Santiago.Perfecta para todo tipo de huéspedes: familias, viajeros de trabajo, estudiantes, personas que vienen a citas médicas o quienes buscan un espacio tranquilo y accesible. La casa está ubicada muy cerca del Hospital Dr. Chicho Fábrega, Clínica Norte, U.Latina, Oxford School, Comercios Supermercados, farmacia, ,restaurantes, y minutos de Santiago centro. Un lugar seguro para estadías cortas y de larga estancia.

Country House in Olá, rivers, waterfalls, Los Picachos
Finca La Terapia lives up to its name, nestled among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day-to-day life of the city. It has 42 private hectares to explore nature. The district of Olá is characterized by having the most beautiful natural landscapes among which we can mention, Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the Finca.

Private Villa with private pool, in Santa Catalina
A beautiful stand-alone 60 sq mt villa, 1 King bed and 1 queen. King size bed in the master bedroom with black out drapes, Queen size bed and fold out couch in the loft area. Full kitchen, living and dining area, flat screen TV, Bathroom with soaps/shampoos, and rainfall showerhead. Large terrace with views as far as the eye can see, with BBQ, dining table and outdoor sectional sofa. Private swimming pool with seating area, pool lounge chairs, lighted gazebo and sun umbrellas.

Mountain retreat
Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Santa Fe villa with a espectacular view
Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

k* Casa Matilde | 2BR Santa Fe Retreat by River
Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

La Yeguada - Forest Point Cabin
Lleva a toda la familia a este fantástico lugar con muchas zonas para divertirse, totalmente equipada cabaña de campo con cocina amplia, sala de estar con acceso a televisión, hamacas, refrigerador, estufa, agua caliente y todo lo que necesitas para pasar un buen momento alejado del ruido y convivir con la naturaleza.

d'rosas apartamentos 3PB
Discover the comfort in our cozy home in the heart of Santiago, Veraguas. Just a 5 minute walk from downtown, you'll enjoy a well-equipped space that includes all the necessary amenities for a relaxing stay. Ideal for exploring local culture and resting after a day of adventure. We look forward to seeing you!

Mansion in Granja Orgánica Climatized Pool
Relax with the whole family and friends up to 30 people in this cozy house on an organic farm with animals, seedlings, tilapia fishing, coffee , rivers, we have a heated pool, roofed terrace of 120 meters to celebrate your special occasions.

Cabana Vergara Santa Fe
Kick back and relax on this 2 acre ( 1 hectare) private mountain side property, on the Santa Maria River. Equipped with all the amenities you will need to make your stay a home away from home!
Popular amenities for La Mesa District holiday rentals
Other great holiday rentals in La Mesa District

Cozy cabin in El Copé

Comfortable rooms in Santiago

Lovely place to stay

Rural Tourism -Casita de Campo-El Copé- Las Yayas

Cabaña “Entre Pinos y Montañas” En Herrera “

Country house, La Mismísima

Studio Hotel Gran David

Salamanca Loft
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