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Holiday houses in Los Santos

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Los Santos

Guests agree: these stays are highly rated for location, cleanliness and more.

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Apartment in La Arena
4.89 out of 5 average rating, 9 reviews

Arena’s Village.

¡Reserva tu estancia en nuestro acogedor espacio hoy mismo! Nuestro Apartamento esta en LA PARTE POSTERIOR DE UNA RESIDENCIA, Y con estacionamiento está convenientemente ubicada céntrico y con todos los servicios que necesitas para unas vacaciones cómodas y relajantes. Ofrecemos horarios flexibles de entrada y salida para que puedas planificar tu viaje en torno a tu horario. con nuestros precios competitivos y excelenreseñas, no puedes salir mal. No pierdas esta oportunidad de experimentar.

Superhost
A wooden decoration is positioned on the bedspread, showcasing the words 'With Love Made in Panama.' The bed features a wooden headboard, complemented by a bedside lamp. Soft blankets and neutral-colored walls create a cozy sleeping environment.
Holiday home in Chitre
4.9 out of 5 average rating, 80 reviews

CASA EdditA ° Cozy house in Chitré

° CASA EDDITA ° Fully equipped house for your enjoyment. Spacious, cool, and cozy in one of the best-located residential areas of Chitré, close to everything: supermarkets, casinos, and a bus terminal. If you are thinking of touring Azuero, we suggest you stop at Casa Eddita, visit downtown Chitré, its handicrafts, cathedral and its variety of typical foods; from here you will be only 1:30 hr from the best beaches of Azuero in Pedasí (Playa Venao and Isla Iguana) Welcome!

Superhost
The house exterior features a warm peach-colored facade with a large white-framed window. Tropical palm trees and vibrant flowering shrubs border the front, providing a refreshing touch to the entrance.
Home in Chitre
4.81 out of 5 average rating, 80 reviews

NinaHouse, spacious and cool house in Chitré.

House just for you, now with a water tank! Up to 7 people, spacious and in one of the best areas of Chitré, quiet and family-friendly, access to the pool in the social area, parks and courts, close to everything: supermarkets, casino, bus; come to Chitre and enjoy typical meals, crafts; plan your walks and visit the best beaches: Pedasi, Venao, Isla Iguana, you can work from NinaHouse with fast internet. We now have air conditioning in the living room for your comfort.

Guest favourite
Apartment in La Villa de los Santos
4.86 out of 5 average rating, 7 reviews

La Villa accommodation for 2 people

Enjoy a comfortable and peaceful stay in this apartment located in the heart of La Villa de Los Santos. Perfect for couples or travelers looking for relaxation and a great location. The space includes: • 1 bedroom with comfortable bed • 1 private bathroom • Living room with TV • Equipped kitchen • Dining room 📍 Central location, close to shops and key attractions. 🔒 Note: The property has a second bedroom that will not be available for this booking option.

Guest favourite
Home in Monagrillo
4.85 out of 5 average rating, 20 reviews

Los 4 Caminos Village #1

✨ Escape ideal en Monagrillo, Chitré Disfruta de la tranquilidad y comodidad de esta residencia completa, perfecta para familias, parejas o grupos. Con capacidad para 6 huéspedes, aire acondicionado, TV HD y wifi, ofrece un ambiente acogedor y funcional. Disfruta de terraza, hamaca, área de juegos y estacionamiento. Pet-friendly y con check-in autónomo, es el lugar perfecto para relajarte, compartir y sentirte como en casa.

Guest favourite
Home in Chitre
5 out of 5 average rating, 11 reviews

Casa Blu Central Chitre| Sleeps 6| Private Parking

Stay in a newly renovated private home in the center of Chitré with free gated parking, a large backyard, fast Wi-Fi, and space for the whole family. Walk to restaurants, supermarkets and the cathedral while enjoying the comfort of an entire home to yourselves. It combines comfort, spaciousness, and natural light in every corner — perfect for families or groups of friends looking for a place that feels just like home.

Superhost
A single-story house with a red-tiled roof and beige exterior is featured. Two white columns support a covered entrance, and a small plant is positioned near the front door. The driveway is made of concrete, leading up to a well-maintained yard with green grass.
Home in Monagrillo
4.83 out of 5 average rating, 53 reviews

Our Happy Place

Relax with the whole family in this quiet place to stay. It is a single-family residence, in the master bedroom we have a Queen bed (1.50 m x 1.90 m) in the second bedroom we have 2 Twin beds (90 m x 1.90 m). The residence can comfortably accommodate 4 people, however we have a sofa bed and a Pee bed available for 2 additional people. Check the small extra cost for additional people.

Superhost
Cottage in Parita District
4.79 out of 5 average rating, 48 reviews

Colonial House in Parita

Discover the charm of Parita from a comfortable and spacious home, perfect for large groups. Located in the picturesque and peaceful town of Parita, in the Herrera Province, just 12 minutes from Chitré, this spacious home is the ideal place to immerse yourself in the history and culture of a historic colonial-era town.

Guest favourite
Apartment in La Villa de los Santos
4.89 out of 5 average rating, 9 reviews

Victoria Apartment #2

In Victoria Apartment No. 2 You will find a quiet accommodation very close to the Church and Simón Bolívar Park, places where the different and renowned festivals of Villa de Los Santos are concentrated. You will also find a lot of comfort with good internet, which makes it a place to enjoy as a family or for work.

Home in La Villa de los Santos
5 out of 5 average rating, 4 reviews

Casa familiar para 9 | 3 habitaciones | Los Santos

Casa completa para hasta 9 huéspedes en Los Santos. A solo minutos de la Feria de Azuero. Disfruta de 3 habitaciones, 2 baños, aire acondicionado, WiFi de alta velocidad, cocina equipada y estacionamiento privado. Ideal para familias, grupos y viajeros que buscan comodidad y excelente ubicación.

Guest favourite
Home in La Villa de los Santos
4.93 out of 5 average rating, 117 reviews

Spacious house in Villa de los Santos

Comfortable family accommodation in La Villa de Los Santos, with Wi-Fi, A/C, equipped kitchen, patio and parking. Located near supermarkets and plazas. Only 15 minutes from El Rompió and Monagre, 45 minutes from Isla Iguana and 1h 30 minutes from Playa Venao.

Top Guest favourite
Apartment in Chitre
5 out of 5 average rating, 6 reviews

Hermoso Departamento completamente independiente.

Apartamento amplio y tranquilo de 2 habitaciones, 2 camas y 1 baño. Excelente ubicación, cerca de restaurantes y servicios. Disfruta de parque, cancha de básquet, juegos para niños y área para perros. ¡Ideal para descansar!

Popular amenities for Los Santos holiday rentals