
Guesthouse holiday rentals in Los Santos Province
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Top-rated Guesthouses in Los Santos Province
Guests agree: These guesthouses are highly rated for location, cleanliness and more.

A Remote Paradise in nature - Ocean View
'Tres-Palmas' sea and nature at its best! A remote hideaway on the Pacific Coast of Panama, but yet close enough to nearby towns and entertainment, Tres Palmas is the perfect place for an invigorating holiday. It is more than just a place to stay, we offer our guests personalized attention through fully equipped facilities and services for your comfort and well being. We enjoy getting to know our guests, sharing life stories and greeting you with an authentic smile for an unforgettable stay.

Cozy & quiet cabin in Cañas
It is a cozy one-bedroom unit, with a closet, a bathroom with separated toilet area, a porch and a rancho. Nestled amidst the serene hills of Canas, the property offers a tranquil retreat with a picturesque ocean view. Wake up to the enchanting melodies of howler monkeys and local birds, immersing yourself in the beauty of nature every morning. While the cabana doesn’t have its own kitchenette, fret not! You’ll have access to a nearby fully equipped community kitchen, shared between 2-3 people.

Alma Residencia - Jungle & 5 minute walk to beach
Alma Residencia is a calm & comfortable retreat for surfers, artists, and nature lovers. Nestled between jungle mountains and the ocean, our space offers a simple, peaceful base to rest, create, & explore Cambutal. WiFi, A/C, & the convenience of Pizzería Madera (Jan - May) located on-site. Spend your days surfing, hiking, or spotting wildlife, and your evenings stargazing under clear skies. A warm, natural escape—just minutes from the beach and surrounded by the beauty of the jungle.

A beautiful beachfront guest house
A perfect jungle-ocean sanctuary in Playa Venao, right across from the main surf point. Open views of the ocean and jungle, tropical vibes, one minute from the surf break and a short walk to town—secluded enough for peace, but close enough to enjoy the action, especially during Venao’s legendary festival weekends. Venao’s green season (roughly May–December-ish) is stunning—nature at its peak. And from around July to October-ish, you can literally watch whales from bed, daily.

Ginger House/House for a violinist
Relax in this unique and peaceful getaway in a private neighborhood. Just a 5-minute walk to the beach, from the house you can hear the water of the creek and the birds singing in the trees, allowing you to enjoy the nature and tranquility of the surroundings. The accommodation features a large terrace with a barbecue area, an outdoor bathroom and shower, and a deck overlooking the creek. Ideal for nature lovers, remote work, surfing, yoga, meditation, hiking, and fishing.

Tiger Beach Cottage + Detached Room @ Los Buzos
A relaxing getaway for a whole group or family right across the beach. Located at Los Buzos Resort and its world famous fishing & adventure lodge where guests have direct access to the many activities and amenities it has to offer like its 400 acre private nature reserve Parque Los Buzos where guests can experience the lush Panamanian wilderness and wildlife on more than 40k of trails. Los Buzos has many thrilling activities waiting. We live where the adventure is.

Accommodation in Las Tablas
Disfruta de la sencillez de este alojamiento tranquilo y céntrico. A solo 10 minutos caminando del centro del pueblo de Las Tablas, cuna de la cultura y folklore panameño con sus actividades y festividades. Ofrece los servicios básicos para cortas estancias. El propietario puede brindar información al huésped para visitar playas cercanas e indicar medios de transportes para visitar distritos cercanos como Pedasí y actividades de interes en la provincia.

Country House with Pool in La Enea de Guararé
Far from the capital city, come to enjoy Panamanian folklore in a rustic but cozy space living a native experience. Lounge in the pool or lounge in a hammock, breathe fresh air, close to the ocean, surrounded by wide, natural gardens for a good walk. Close to the Puerto de Guararé where you will enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian chickens.

La Casita del Abuelo
This private place with full private bathroom is perfect for solo adventurers or a couple, seeking peace and relaxation in an authentic environment near the beach and town. This cute hideaway is located minutes’ walks from town and bus stop and about two miles from the nearest beach. It is a new, very clean, private, secure place, and it includes private use of an adjacent bohio with hammocks, barbecue grill, and bar.

"La Jungla" Cabaña close to the beach
New room with shared kitchen and private bathroom close to the beach. You can enjoy all that Cambutal has to offer from this place. It has easy access so you dont need 4x4. Its located 500m from the beach, or 5 mins walking. The room has its own little green area and a large bathroom in the back. We try yo be close to nature and have a cool community here. We are happy to welcome new comers and old faces to Cambutal :)

Casita Verde 411
Ocean View Jungle Casita • 500 m from 411 Surf Spot • Off-Grid Retreat 🌊🌴 Wake up to waves and tropical birds in our cozy Casita, just a 3-min walk from the famous 411 Surf Spot. Between lush rainforest and the Pacific, this off-grid retreat offers adventure and relaxation. Why You’ll Love It Here: Surf in the morning, relax in the hammock by day, and stargaze at night – far from crowds, surrounded by nature.

Grateful Casita
Take it easy at this unique and tranquil getaway after a day of surfing or exploring. This is a separate casita on my property in a gated community 5 minute drive from Playa Venao. There is a shared small pool. The casita has a small kitchenette area, outside sink and shower, loft with full bed and the best view in Venao!
Popular amenities for Los Santos Province guesthouses
Family-Friendly guesthouses

A beautiful beachfront guest house

Country House with Pool in La Enea de Guararé

Grateful Casita

Apartment-house in Herrera

Bedroom, kitchen, bathroom and terrace

A Remote Paradise in nature - Ocean View

Cozy & quiet cabin in Cañas

"La Jungla" Cabaña close to the beach
Guesthouses with a patio

Casa Pesca

Catch & Relax Cottage @ Los Buzos

Catch & Relax Cottage + Detached Room @ Los Buzos

Las Tablas House Alquiler

Casa Pesca

Fourth Study/Festivities

Tiger Beach Cottage @ Los Buzos

Casa Pesca
Other guest house holiday rentals

A beautiful beachfront guest house

Country House with Pool in La Enea de Guararé

Apartment-house in Herrera

Grateful Casita

Bedroom, kitchen, bathroom and terrace

A Remote Paradise in nature - Ocean View

Cozy & quiet cabin in Cañas

"La Jungla" Cabaña close to the beach
Destinations to explore
- Rentals with outdoor seating Los Santos Province
- Smoking-friendly rentals Los Santos Province
- Bed and breakfasts Los Santos Province
- Pet-friendly rentals Los Santos Province
- Waterfront rentals Los Santos Province
- Rentals with a hot tub Los Santos Province
- Rentals with a washing machine and dryer Los Santos Province
- House rentals Los Santos Province
- Rentals with pools Los Santos Province
- Boutique hotels Los Santos Province
- Beachfront rentals Los Santos Province
- Rentals with beach access Los Santos Province
- Condo rentals Los Santos Province
- Hotel rooms Los Santos Province
- Villa rentals Los Santos Province
- Rentals with a fire pit Los Santos Province
- Apartment rentals Los Santos Province
- Family-friendly rentals Los Santos Province
- Rentals with a patio Los Santos Province
- Rentals with an accessible height bed Los Santos Province
- Guesthouse rentals Panama




