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Holiday houses in Mesopotamia

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
An aerial view showcases a secluded property surrounded by greenery, softly illuminated by outdoor lights at dusk. The house is positioned on a hill, while paths lead to small seating areas enhanced by tropical plants. The inviting layout suggests a peaceful retreat.
Cabin in Peñol
4.9 out of 5 average rating, 103 reviews

Cabaña con jacuzzi y vista a el embalse, 8 pax

Take it easy at this unique and tranquil getaway. This house in a subdivision with 3 spacious rooms, a Jacuzzi, a barbecue, access to the dam, and a stunning view of the Peñol stone ★"My wife explored the options and feels that your beautiful villa is her favorite in El Peñol." - Marcela, September 15 Exclusive condominium with few houses which will provide security during your stay, large terrace for your meetings and enjoyment with family or friends. Very safe and comfortable place Newly furnished☞ house.

Top Guest favourite
A modern structure emerges from lush greenery, framed by vibrant plants and a manicured lawn. Large glass doors lead to a spacious deck, offering a view of the mountains and a colorful sky. Pathway stones create a welcoming entrance.
Home in La Ceja
4.94 out of 5 average rating, 54 reviews

Country house, excellent location, beautiful view!

Te invitamos a disfrutar de un hermoso espacio rodeado de naturaleza, con todas las comodidades para que puedas relajarte y descansar. Te sentirás como en casa. Lugar ideal para hacer teletrabajo (nómadas digitales) y estancias largas. A tan solo 10 minutos de La Ceja, 45 minutos del aeropuerto internacional y a una 1 hora de Medellín. Mascotas son bienvenidas. Adicionalmente ofrecemos clases de Yoga, terapias Ayurvedicas (Abhyanga/Swedana), clases de tenis. Lugar perfecto para turismo "slow"!

Guest favourite
Tiny home in Cocorná
4.95 out of 5 average rating, 39 reviews

Cabin with jacuzzi, private river and natural pool

Enjoy incredible privacy in the beautiful nature of Cocorná. Relax in the jacuzzi or enjoy the beautiful river with a private terrace next to a naturally created pool that belongs exclusively to this property. The cabin features a beautiful bathroom, a king size bed, Wi-fi, a TV with Netflix, and a kitchen equipped with all cooking utensils including a barbecue. We also organize various activities including paragliding and rafting. We offer transportation. Breakfast is included! (to prepare)

Top Guest favourite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny home in Guatape
4.98 out of 5 average rating, 637 reviews

Foresta: Modern cabin overlooking the Rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us, or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the Rock and do kayaking, jet-skiing, wakeboarding, sailing, paraglading, horseback riding, hiking, helicopter tours or ATV rides. You choose!

Guest favourite
Cabin in El Carmen de Viboral
4.94 out of 5 average rating, 71 reviews

Espi Ritual

Step into tranquility and reconnect with nature in this serene Llano Grando cabin. Soak up the patio sun, immerse yourself in the beautiful garden, or spot countless bird species on the sun-deck overlooking the pond. This cabin is equipped with WiFi, a full kitchen, an asador, and a private entrance. The perfect location for a peaceful solo trip, charming romantic getaway, or unique family adventure. 15 minutes from charming San Antonia and near restaurants and shopping

Top Guest favourite
Cabin in Rionegro
5 out of 5 average rating, 32 reviews

Selvva suites | luxury cabin in a forest + jacuzzi

Escape to SELVVA SUITES, a luxury retreat immersed in the tranquility of a native forest, just 50 minutes from Medellín. Located on the Llanogrande–La Ceja road, only 15 minutes from Llanogrande mall and 20 minutes from JMC Airport in Rionegro. Enjoy a King-size bed and a private jacuzzi surrounded by nature. Private parking with easy access for any type of vehicle. ⚠️ ✈️We are in an area with air traffic, and airplane noise can be heard. 🐾 Pet friendly

Top Guest favourite
A charming chalet is depicted beside a serene natural lake, framed by lush greenery and vibrant aquatic plants. The structure features rustic wooden details, large windows, and an expansive deck, inviting outdoor relaxation and enjoyment of the tranquil surroundings.
Cabin in Santa Elena
4.99 out of 5 average rating, 175 reviews

Chalet del Lago | Private Jacuzzi + Nature

🌿 Chalet del Lago – Santa Elena Escápate a un refugio natural con lago privado, amplios ventanales y un entorno lleno de paz. Con un muy completo equipamiento y distribución.A solo 10 minutos del parque principal, disfruta del canto de las aves, el sonido del agua y el clima fresco del campo antioqueño. Ideal para parejas, familias o una escapada de descanso. Naturaleza, tranquilidad y momentos inolvidables en un solo lugar. 💛✨ ✅ Somos pet friendly🐶🐈

Top Guest favourite
Farm stay in Cocorná
4.98 out of 5 average rating, 41 reviews

Bali-style cabin with forest and private river

Bali-style cabin with more than 2 hectares of private forest and river, hot Jacuzzi, wifi, spring climate, combining luxury and nature, deck next to the river, campfire, cinema-type video projector, shower with a view of nature, work and reading area, beautiful night lighting, kitchen and BBQ area, sun loungers and many other details designed to give you a unique experience and invite you to slow down and reconnect with yourself and nature

Top Guest favourite
Cabin in Rionegro
4.98 out of 5 average rating, 100 reviews

Nature & View | Cabin with Jacuzzi and Nature

Enjoy an unforgettable experience in our private cabin, located just 8 minutes from José María Córdova International Airport. Enjoy a panoramic view of the city and relax in your private Jacuzzi. The cabin is equipped with a full kitchen, fast wifi, workspace and self check-in. You will find several nearby restaurants with home delivery, and inside the accommodation we have drinks and snacks to buy. 🚘 Trusted Uber driver

Top Guest favourite
Chalet in Antioquia
4.96 out of 5 average rating, 330 reviews

Cabin with Jacuzzi 8 min from JMC Airport

Welcome to Quimera Ecolodge, a charming chalet located in a natural paradise paradise just 10 minutes from José María Córdova Airport. At Quimera Ecolodge, every corner has been designed to offer you a unique experience, combining comfort, sustainability, and an authentic connection with the natural environment, ideal for those who want to escape the hustle and bustle of the city without losing proximity to comfort.

Guest favourite
Farm stay in Rionegro
4.95 out of 5 average rating, 300 reviews

Lumberjack's House | Secluded nature retreat

🪓 Retiro Cabin – Casa del Leñador is the house of our dreams. A small, cozy tiny home surrounded by nature. The perfect place to spend a few days as a couple, a family weekend, or work remotely in an environment without distractions. Wake up to birdsong at dawn and enjoy a campfire on the deck at dusk. At Retiro Cabin you will have total independence and an unparalleled view of the countryside in eastern Antioquia.

Top Guest favourite
A single-story house surrounded by lush greenery is showcased. The exterior features a welcoming porch with seating and a hammock. The structure boasts large windows for natural light, while landscaped bushes and trees frame the property, enhancing the serene rural setting.
Farm stay in El Carmen de Viboral
4.97 out of 5 average rating, 106 reviews

☼♥Villa Serena ♥☼ 360° Views-Nature-Serenity

* An incredible house with gorgeous 360° views* * Private Deck. Views of valley/Airport * Mountain views * Privacy gate. Alarm. Parking for 2 Cars * Fully stocked and equipped kitchen * 1 km / 0.6-mile dirt road to the house (any car will access) * There are two homes on the property, the main, larger house is Villa Serena where you will stay, the second home has a separate entrance and is not offered in Airbnb.

Popular amenities for Mesopotamia holiday rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia