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Holiday houses in Mesopotamia

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Mesopotamia

Guests agree: these stays are highly rated for location, cleanliness and more.

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Superhost
A spacious wooden bedroom features a king bed adorned with light bedding, complemented by textured walls and a rustic wood ceiling. A colorful hammock hangs across the room, and natural light filters in through a window, enhancing the cozy ambiance.
Treehouse in Retiro
4.89 out of 5 average rating, 108 reviews

A wooden cabin in the El Retiro Antioquia forest

Imagine sleeping in a wooden cabin in a king-size bed with the lull of the river's sound. When you wake up you will feel like you are in a treehouse overlooking the snowflakes full of birds, going down to the garden with bare feet, having breakfast on the deck and seeing the horizon. During the day, walk, go to the river and the waterfall, get to the stone bathroom and the whirlpool, sit in the hammock, read, and at night light the fireplace (salamander), have a glass of wine at the kitchen counter with your partner, family, and friends.

Top Guest favourite
A modern cabin is positioned on a hillside, surrounded by lush greenery and offering panoramic views of the surrounding landscape, including a prominent rock formation and a serene body of water in the foreground.
Tiny home in Guatape
4.98 out of 5 average rating, 612 reviews

Foresta: Modern cabin with views of the rock

FORESTA is a modern cabin created with love for you to have an unforgettable stay in the middle of nature, with total comfort. Enjoy the privileged views from the deck, chill out in the jacuzzi, watch the dozens of birds that visit us or have a chat by the fireplace in the living room. FORESTA is a great launchpad to explore Guatape, climb the rock and do kayaking, jet-ski, wakeboard, sailing, paraglading, horseback riding, hiking, getting a helicopter ride or having an ATV tour. You choose!

Guest favourite
Villa in Peñol
4.92 out of 5 average rating, 147 reviews

Private luxury Retreat Guatape,lake access

Our concept is privacy and comfort in the middle of nature, each room has a high standard king bed for your comfort, all rooms have a direct view of the lake, balcony and private bathroom; the jacuzzi located at the top of the mountain under the imposing eucalyptus trees . You will enter to the house through the roof, to findh a wonderful view of the lake, we have .created tailor-made experiences, traditional cuisine, a chef, water activities, and our spa. Paddle boards and canoe are included

Top Guest favourite
Cottage in Vereda Los Naranjos
4.97 out of 5 average rating, 142 reviews

Finca Colibri Guatape Artist Lakehouse Charm

Finca Colibiri is one of the most unique homes in Guatape, lived in and designed by artists. Wake up in nature to the sounds of singing birds and fish jumping. Spectacular lake views from a private bay. Enjoy combined indoor and outdoor living in the gorgeous open spaces. Prepare for a peaceful sleep with top beds and linens where the silence allows for just the chirping of frogs and natural sounds of other local fauna. Perfect for a retreat from the city or a long stay as an artist residence.

Guest favourite
Tiny home in Cocorná
4.92 out of 5 average rating, 26 reviews

Cabin with jacuzzi, private river and natural pool

Enjoy incredible privacy in the beautiful nature of Cocorná. Relax in the jacuzzi or enjoy the beautiful river with a private terrace next to a naturally created pool that belongs exclusively to this property. The cabin features a beautiful bathroom, a king size bed, Wi-fi, a TV with Netflix, and a kitchen equipped with all cooking utensils including a barbecue. We also organize various activities including paragliding and rafting. We offer transportation. Breakfast is included! (to prepare)

Top Guest favourite
An outdoor dining area features a wooden table set with dishes in a tranquil garden setting. Nearby, a mini hot water pool is visible, surrounded by lush greenery and steps leading to additional seating areas. Natural elements enhance the serene ambiance.
Cabin in El Peñol
5 out of 5 average rating, 301 reviews

Milagros Home-Mini private heated pool!

🍃Una experiencia privada, no solo una cabaña. Milagros Home es una cabaña artesanal moderna con muchos espacios en un solo lugar, con vista privilegiada al embalse de El Peñol-Guatapé, lo que te permite disfrutar de un paisaje y unos amaneceres de ensueño. Ni con las mejores fotografías te puedo explicar lo que se siente estar aquí, es un lugar donde sientes que se detiene el tiempo y te haces uno con el entorno. Aquí no compartes espacios es una sola cabaña completamente para ti.🍃

Guest favourite
A view from above showcases the spacious deck overlooking the lake. The wooden floor connects to a cozy living area, while large glass panels allow natural light and scenic views of nearby greenery and the water.
Cabin in Peñol
4.86 out of 5 average rating, 170 reviews

Cabin with Jacuzzi and access to the reservoir for couples

Chalet-type cabin for two people, in front of the reservoir, with a jacuzzi and an interior design full of details. Portum is located on a 3300 m2 plot of land, facing the El Peñol-Guatapé reservoir, with access to the reservoir and dock, native trees and gardens. There are two other small cabins on the property that are also rented by Airbnb. At this time the reservoir has a high percentage of filling, having an excellent view from the cabin The area has a tourist neighborhood

Superhost
Chalet in Plan
4.88 out of 5 average rating, 130 reviews

cloud forest cabin with fireplace

Just 40 minutes from Medellín, our chalets combine the rustic charm of Santa Elena with all the modern comforts you need. Each chalet is fully furnished and equipped, featuring high-speed internet, hot water, and private parking. You’ll have easy access to public transportation, local shops and markets, as well as cafés and restaurants within walking distance. Perfect for romantic getaways, remote work, or simply reconnecting with yourself in a natural and cozy setting

Top Guest favourite
A charming chalet is depicted beside a serene natural lake, framed by lush greenery and vibrant aquatic plants. The structure features rustic wooden details, large windows, and an expansive deck, inviting outdoor relaxation and enjoyment of the tranquil surroundings.
Cabin in Santa Elena
4.99 out of 5 average rating, 164 reviews

Chalet del Lago | Private Jacuzzi + Nature

🌿 Chalet del Lago – Santa Elena Escápate a un refugio natural con lago privado, amplios ventanales y un entorno lleno de paz. Con un muy completo equipamiento y distribución.A solo 10 minutos del parque principal, disfruta del canto de las aves, el sonido del agua y el clima fresco del campo antioqueño. Ideal para parejas, familias o una escapada de descanso. Naturaleza, tranquilidad y momentos inolvidables en un solo lugar. 💛✨ ✅ Somos pet friendly🐶🐈

Top Guest favourite
Cabin in Rionegro
4.95 out of 5 average rating, 322 reviews

Nature & View | Cabin with a view

Nature & View just 8 min from JMC Airport Ideal for couples or travelers in transit. Our cabin offers a view of the valley, a quiet atmosphere, self check-in, an equipped kitchen, fast wifi, and all the comforts to relax. For your convenience, there are restaurants with home delivery and inside the accommodation you can buy cold drinks and snacks when you need them. 🚘 Trusted Uber driver Relax, order your favorite food and enjoy the view. Book your date!

Top Guest favourite
A single-story house surrounded by lush greenery is showcased. The exterior features a welcoming porch with seating and a hammock. The structure boasts large windows for natural light, while landscaped bushes and trees frame the property, enhancing the serene rural setting.
Farm stay in El Carmen de Viboral
4.97 out of 5 average rating, 105 reviews

☼♥Villa Serena ♥☼ 360° Views-Nature-Serenity

* An incredible house with gorgeous 360° views* * 143 m² / 1539 ft² house size * Private Deck. Views of valley/Rionegro/Airport * Views of mountains * Privacy gate. Alarm. Parking for 5+ Cars * Fully stocked and equipped kitchen * 1 km / 0.6-mile dirt road to the house (any car will access) * There are two homes on the property, the main, larger house is Villa Serena where you will stay, the second home has a separate entrance and is not offered in Airbnb.

Top Guest favourite
Chalet in Antioquia
4.96 out of 5 average rating, 315 reviews

Cabin with Jacuzzi 8 min from JMC Airport

Welcome to Quimera Ecolodge, a charming chalet located in a natural paradise paradise just 10 minutes from José María Córdova Airport. At Quimera Ecolodge, every corner has been designed to offer you a unique experience, combining comfort, sustainability, and an authentic connection with the natural environment, ideal for those who want to escape the hustle and bustle of the city without losing proximity to comfort.

Popular amenities for Mesopotamia holiday rentals

  1. Airbnb
  2. Colombia
  3. Antioquia
  4. Mesopotamia