
Holiday houses in Panama Canal
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Top-rated holiday rentals in Panama Canal
Guests agree: these stays are highly rated for location, cleanliness and more.

In the heart of Casco, refurbished and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

In the Heart of Panama Pacifico
🪷Conoce este encantador apartamento de una habitación en el corazón de Panamá Pacífico. Cocina, baño elegante y un cómodo sofá cama en el den, refugio perfecto para quienes buscan comodidad y funcionalidad. Solo unos pasos, tendrás acceso a supermercados, restaurantes, Starbucks, farmacias y más. Ideal para quienes desean un espacio tranquilo, rodeado de naturaleza, pero con fácil acceso a la ciudad. Disfruta de la paz del entorno verde y la conveniencia de estar cerca de todas las comodidades

Gamboa Toucan Apartment casa # 126
Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Tropicool Loft w/rooftop steps from Casco
This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Large Apartment in La Cuadra - Casco | By Alura
El Casco Antiguo de Panamá es uno de los barrios más encantadores y vibrantes de la ciudad. Declarado Patrimonio de la Humanidad por la UNESCO. El Apartamento El espacio combina líneas modernas con detalles originales del barrio. Cuenta con una distribución luminosa, cocina equipada, sala amplia y acabados pensados para brindar comodidad. Posee un dormitorio con cama king y un hermoso balcón. Es ideal para quienes buscan vivir una experiencia auténtica en el Casco Antiguo.

Gorgeous Flat in the best location in Casco Viejo
This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

New apartment in the heart of Panama
Comfort, location and tranquility in new accommodation, in the financial center of Panama, close to Calle 50 and the emblematic El Tornillo building. All modern amenities, close to hotels, casinos, restaurants and with a completely safe area to walk. Swimming pool and gym on the top floor with spectacular city views. Easy access: from the airport Metro or land terminal you can reach the station via Argentina located 400 meters from the apartment.

Private parking & rooftop | Studio Casco Center
This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Modern apartment in the Historic Center
I invite you to this apartment in La Manzana, Santa Ana. This place is strategically located - it will be very easy to plan your visit! It is only a 2-minute walk from the Old Town. Our studio offers an ideal location to enjoy the Historic District and the entire city. We have Wi-Fi, a hotel bed, a fully equipped kitchen, a space to work, a TV, and a hot shower. In addition, the building has 24 hour security so you have nothing to worry about!!

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Beautiful apartment in Casco Viejo ST. George D
Welcome to our spacious and charming apartment in Casco Viejo. Located in a vibrant and historic neighborhood. You will love the warm atmosphere created by the lime and pebble walls, in perfect harmony with our modern and elegant decor. The space is large and comfortable, ideal for relaxing after a day exploring the city. As a host, I'm available 24/7 to answer questions and make sure you make the most of your stay.
Popular amenities for Panama Canal holiday rentals
Other great holiday rentals in Panama Canal

Elegant Apt in Costa del Este. Premium Amenities

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w* | Luxury 2BR in Old Town

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Amazing experience in Casco Viejo historical site3

Exclusive & luxury 1BR with balcony in Yoo Panama

180° Old Town Views, Pool & Coworking
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