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Holiday houses in Panama Canal

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Top-rated holiday rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Apartment in San Felipe

In the heart of Casco, refurbished and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

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4.96 out of 5 average rating, 263 reviews
Top Guest favourite
Apartment in Panama City

Albrook Palms | Apartment + 2 Suites 4BR/4BA

Welcome to Albrook Palms & Suites. Enjoy our spacious apartment + 2 suites in a historic Albrook three-story duplex. • Ground level offers two private guest suites with en suite bathrooms. • Second floor features a 2BR/2BA apartment with full kitchen, living/ dining area & balcony (adult supervision required). • Third floor is occupied by the property caretaker and not part of the rental. • Guests share common areas with caretaker including stairs, laundry room and yard.

LocationFamilyHospitality

4.94 out of 5 average rating, 17 reviews
Guest favourite
Apartment in Panama City

Ocean View | Rooftop Pool | Luxury Stay

Wake up to a stunning ocean view right from your window at BrisaMarina. This luxury apartment is located in the spectacular The Sands building, right on the Cinta Costera. The modern and cozy space features bright natural light, air conditioning, high-speed Wi-Fi, and a fully equipped kitchen for your comfort. You’ll be just minutes away from restaurants, beaches, and top attractions. Perfect for couples, business travelers, or weekend getaways.

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4.97 out of 5 average rating, 97 reviews
Top Guest favourite
A cozy living area features a bright yellow armchair beside a sleek media console. A modern television is mounted above the console, which displays green foliage. The floor is adorned with a patterned rug, while the textured stone wall adds a rustic charm to the space.
Place to stay in San Felipe

Loft in Casco Antiguo, Joya Colonial

Welcome to a space where history, design and comfort merge in one of Panama's most iconic neighborhoods. This apartment, located in the heart of the Old Town, immerses you in the rich colonial culture and architecture, while offering you all the modern amenities for an unforgettable stay. ✔ Spacious ✔ Classic-modern design ✔ Equipped kitchen ✔ Private balcony ✔ Dreamy master bedroom ✔ High-speed WiFi and Smart TV ✔ An unbeatable location

LocationValueIndoor spaces

4.95 out of 5 average rating, 104 reviews
Guest favourite
A spacious living area features light wood flooring and a modern open kitchen. Two light-colored sofas surround a marble coffee table, while a dining area with a stylish table sits nearby. A spiral staircase leads to the upper level, and decorative artwork adorns the walls.
Loft in San Felipe

Loft 3b Old Town Best! It's 150 m2 (492 feet)

Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

LocationValueAir conditioning

4.93 out of 5 average rating, 126 reviews
Superhost
An interior view showcases a modern, multi-level loft with a wooden staircase leading to the upper loft area. Soft lighting creates ambient hues throughout the open space, highlighting the kitchen and living areas, where stylish furniture is arranged for comfort. Exposed stone walls add texture.
Loft in Panama City

2B Loft Studio | Design By Paradox

Private 40 m² loft studio in Santa Ana, about a 5-minute walk from Casco Viejo. Loft Studio sleeps up to 3 guests with a Queen bed on a mezzanine and a sofa bed, plus a full kitchen, private bathroom, air conditioning, hot water, fast WiFi, dining space, and a 1.8 m desk. Enjoy a TV with Roku and host-provided Netflix, Disney+, Max, and Prime. Guests have access to the shared balcony, patio, and paid laundry.

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4.89 out of 5 average rating, 360 reviews
Guest favourite
Home in Gamboa

BirdHouse — Gamboa, Panama Canal Rainforest

BirdHouse: Let's inhabit the space. Designed for people who want to experience the tropics, not shut them out. Open the screens, feel the breeze, listen to the rain, cool off in the pool, and wake to birds and howler monkeys. Located in historic Gamboa, BirdHouse is a place to slow down and experience one of the world’s richest tropical forests from the comfort of a thoughtfully designed home.

LocationFamilyKitchen

4.86 out of 5 average rating, 111 reviews
Guest favourite
Apartment in Panama City

Balboa Avenue Sky Suites

Modern Apartment with Spectacular Views on Balboa Avenue | 2 Bedrooms, 2 Bathrooms Welcome to your home in the heart of the city, where luxury, comfort and breathtaking views combine to offer you a unique experience. This elegant 2 bedroom, 2 bathroom apartment is located in the exclusive PH The Sands Apartments & Mall on Avenida Balboa, one of Panama's most coveted destinations.

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4.92 out of 5 average rating, 64 reviews
Top Guest favourite
A spacious living area features a dark dining table set for six, adorned with gold charger plates. In the background, a large beige sofa contrasts with the light-colored walls. Natural light is complemented by modern light fixtures, enhancing the openness of the space.
Apartment in El Cangrejo

Nice & Cozy 3-Bedroom Apartment!

Centric Apartment in the Heart of the City! This building is located in El Cangrejo, a centric, friendly neighborhood filled with a variety of restaurants, bars, casinos and shops. Everything you need is within a 5 minute walk. Popular areas such as Casco Viejo, the Panama Canal Locks, Causeway and main shopping malls are within a 10 minute drive.

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4.93 out of 5 average rating, 134 reviews
Top Guest favourite
A cozy living area is highlighted by a light-colored wooden table placed on a textured rug. Two comfortable chairs face the table, with a small plant centerpiece and books visible. Natural light floods the space through large windows, revealing lush greenery outside.
Loft in Panama City

Canal Loft

Apartment on 1st floor, ideal for couples who love good taste, tranquility and comfort. Nearby to the apartment there are trails to the Panama Canal, hills and jungle. Apartment on the 1st Floor, ideal for couples who love good taste, tranquility and comfort. Near the apartment there are trails to the Panama Canal, hills and jungle.

ValueLocationHospitality

4.95 out of 5 average rating, 86 reviews
Top Guest favourite
A spacious living area features a comfortable gray sofa and a stylish wooden coffee table. A swing chair hangs beside a large window, providing natural light. The dining area, with a wooden table and black chairs, is seen in the background, enhancing the open layout.
Home in Gamboa

Family home in Gamboa next to the Canal

Gamboa was founded in the 1930s by Americans from the old Panama Canal area. Forget your worries in this spacious and serene space. Enjoy walks on the Panama Canal and Gatun Lake. Birdwatching and hiking trails surrounded by fauna and vegetation.

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4.91 out of 5 average rating, 69 reviews
Guest favourite
Apartment in Panama City

Panama City Ocean View

Stunning views of the ocean and the Old Town, with direct access to the Poin Panamá resort, as well as a variety of dining options and bars, for an unparalleled vacation experience.

LocationPoolLaundry

4.94 out of 5 average rating, 17 reviews

Popular amenities for Panama Canal holiday rentals