My place is in Friedrichshain, just around the corner from Frankfurter Tor and Simon-Dach Strasse, and up the street the East Side Gallery, and the Mercedes Benz Arena.
It's very centrally located with tram, bus, and S/U Bahn stops nearby. The neighborhood is filled with bars, restaurants and a number of other Berlin attractions, all within walking distance.
My place is good for couples, solo adventurers, and business travelers. There are two 140x200 beds, so up to 4 people could stay.