My place is close to One Stop Beer Shop, which has to be one of the best bars in NYC. It's a big, private studio with separate kitchen and bathroom, high ceilings, a comfy bed and couches, and it's on the ground level -- no climbing up flights of stairs. It's a safe, quiet neighborhood, but still close to the heart of Williamsburg. I've loved it ever since I started living in it.
Laptop friendly workspace