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Holiday houses in San Antonio

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Top-rated holiday rentals in San Antonio

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A bright and airy room features two full-size beds with crisp white linens and decorative pillows. A wooden dining table with four chairs is positioned nearby. Fresh towels are neatly arranged on the beds. A small kitchenette is subtly integrated into the space.
Apartment in Los Canelos
4.8 out of 5 average rating, 40 reviews

Salamanca Loft

Este hermoso apartamento esta ubicado en el centro de todo Panamá en la hermosa provincia de Herrera, vía interamericana, a pocos minutos de varias ciudades como Chitré, Aguadulce y Santiago. En un ambiente tranquilo, rodeado de árboles. Si corren con suerte podrán observar desde lejos las hermosas iguanas que se pasean por las ramas mas altas. Pueden apreciar al caer la tarde una hermosa puesta del sol. Justo al frente, hay cafetería, también hay pizzerías a domicilio y restaurantes.

An outdoor bathroom is enclosed by bamboo walls and natural stone, featuring a wooden basin and a unique circular shower area. Smooth pebbles create a textured border around the space, enhancing its connection to nature.
Cabin in Santa Fe
4.67 out of 5 average rating, 27 reviews

Treehouse

Come relax in this unique logging overlooking the Santa Maria's river. Immerse yourself in nature while having the comfort of quality beds and furniture. Ideal to spend a few nights when you are traveling or a long stay if you feel like reconnecting with what is essential. This beautiful habitat will rock you into the sounds and smells of Panama's mountain's soft nature. Outside kitchen and bathroom. Optional relax massage. Two queen size bed.

A spacious studio is presented, featuring a comfortable sofa and a queen bed with an elegant headboard. A flat-screen TV is mounted on the wall opposite. A small table and chairs are arranged near the sofa, providing a cozy seating area within the bright space.
Apartment in Santiago
5 out of 5 average rating, 4 reviews

Studio Hotel Gran David

This studio is located behind the Hotel Gran David, which is located in a very convenient location (Carretera Panamericana). However, this studio is located on a very quiet area at the back part of the hotel. Although the studio has an independent entrance to that of the hotel, you can still use all the amenities of the hotel (swimming pool and gym), and have easy access to the hotel's two restaurants, pool bar and bar.

A cozy corner is shown with a light-toned futon, paired with a small wooden table and two modern chairs. Natural light enters through two windows, complementing the warm wooden paneling on one wall.
Condo in Panama City
4.67 out of 5 average rating, 30 reviews

Departamento 2E - BEST place in town.

Accessible apartment in the heart of Santiago, located 300m from the Central Bus Station and within walking distance of supermarkets and businesses. With good distribution of space, fresh and illuminated and with all basic services. The apartments provide a harmonious balance in the middle of the rush characteristic of the city, perfect for stays of families, friends, professionals, couples.

Superhost
Home in Santiago
4.22 out of 5 average rating, 9 reviews

Peaceful, Clean, and Conveniently Located House

This house is located in a quiet location on the edge of the city of Santiago about 10 minutes walking distance from the main shopping area of Central Ave. The house is fully furnished with air conditioning throughout the entire house. There is also a spacious kitchen with all the necessary appliances. You can enjoy the private backyard as you lay in the hammock.

Superhost
The two-story colonial house is showcased with a white facade and wooden accents. Decorative balconies with railings are present at the front, along with several potted plants adding color. The street is lined with other buildings, under a clear blue sky dotted with clouds.
Cottage in Parita District
4.79 out of 5 average rating, 43 reviews

Colonial House in Parita

Discover the charm of Parita from a comfortable and spacious home, perfect for large groups. Located in the picturesque and peaceful town of Parita, in the Herrera Province, just 12 minutes from Chitré, this spacious home is the ideal place to immerse yourself in the history and culture of a historic colonial-era town.

Superhost
A small dining area is featured with a round table and two folding chairs. Large windows offer views of lush greenery outside, while sheer white curtains partially filter natural light.
Apartment in Santiago
4.88 out of 5 average rating, 8 reviews

d'rosas apartamentos 3PB

Discover the comfort in our cozy home in the heart of Santiago, Veraguas. Just a 5 minute walk from downtown, you'll enjoy a well-equipped space that includes all the necessary amenities for a relaxing stay. Ideal for exploring local culture and resting after a day of adventure. We look forward to seeing you!

Apartment in Santiago
4.83 out of 5 average rating, 6 reviews

Accommodation in Santiago Centro

Enjoy the easy access to everything from this perfectly located accommodation, in the center of Santiago 2 minutes from the cathedral church, park, and the central Ave. Fresh and comfortable on the ground floor of a property a large terrace with access to the patio surrounded by nature.

A modern single-story home is illuminated at night, showcasing a covered entrance and a smooth driveway. Ambient lighting highlights the exterior design, while large windows provide glimpses of the interior. Surrounding greenery adds to the peaceful atmosphere.
Home in La Arena
4.62 out of 5 average rating, 37 reviews

Kamehouse

Relax with the whole family at this place where tranquility is breathable. A safe, comfortable, beautiful and central place in which you can rest without so many complications, it is also a very pleasant place in sight and functional for work topics.

A charming house is surrounded by lush greenery, featuring tall trees that frame the structure. The red exterior complements the vibrant garden, which includes a variety of colorful plants. A shaded porch invites relaxation, while the expansive lawn offers open space for family activities.
Home in Paris
5 out of 5 average rating, 3 reviews

Casa de Finca

Relax with the whole family in this home where tranquility is breathable. It's a farm house 100 meters from a Grado A milk milking galley. Surrounded by nature with beautiful sunsets and centuries-old trees. It is fully equipped.

A modest exterior view features a white building with dark windows and a welcoming black door. Lush greenery surrounds the entrance, and well-maintained stone pathways lead to the door, highlighting the peaceful outdoor setting.
Home in Santiago
4.86 out of 5 average rating, 21 reviews

2 bedroom house in Santiago

centric, well located, walking distance to downtown. Near the Panama Canal Museum, park Juan Demostenes Arosemana, and the Santiago Cathedral Juan Pablo Apostol. A few meters from central avenue.

Guest favourite
A single-story house features an arched entry with decorative windows. The front porch is equipped with seating, surrounded by greenery. A paved driveway leads to the home, providing access for vehicles, while the roof offers ample shade.
Home in Santiago
4.9 out of 5 average rating, 10 reviews

Casa Nuevo San Juan

Easy access from the Panamericana. It is a central area has supermarket, pharmacy, restaurant, hospital availability.

Popular amenities for San Antonio holiday rentals

  1. Airbnb
  2. Panama
  3. Distrito Atalaya
  4. San Antonio