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Holiday houses in Santa Clara

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Top-rated holiday rentals in Santa Clara

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Apartment in Panamá
4.98 out of 5 average rating, 230 reviews

In the heart of Casco, refurbished and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Top Guest favourite
The living area features large glass doors that invite natural light and views of the garden. Indoor plants enhance the space, and a cozy seating arrangement includes a sofa and eclectic chairs. A workspace with a desk and lamp is positioned to the side.
Guesthouse in El Valle de Antón
4.99 out of 5 average rating, 114 reviews

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Top Guest favourite
A charming apartment building is nestled among lush greenery and tall trees. The exterior features a welcoming porch with railings and is surrounded by tropical plants, creating a serene environment. Natural sunlight filters through the leaves, highlighting the vibrant foliage.
Guesthouse in Gamboa
4.94 out of 5 average rating, 80 reviews

Gamboa Toucan Apartment casa # 126

Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Guest favourite
Apartment in Veracruz
4.89 out of 5 average rating, 9 reviews

On the beach. Entire floor with oceanfront terrace

On the beach with direct access to the sea. Open space studio for 2 people. Living room / kitchen / bedroom 1 (Queen) / sofa / armchair / bathroom with shower, dedicated work space. Large, spectacular terrace on the gulf with bathtub convertible into a sofa. Comfortable, elegant, quiet, and safe. Large and fresh tree-lined garden with tropical fauna and flora. Hummingbirds, iguanas, sometimes monkeys and sloths etc ... Gym equipment, small pool. Perfect for recharging your batteries.

Guest favourite
A scenic view is presented from the balcony, showcasing lush greenery and the town of Gamboa. The Panama Canal and distant hills are visible under a bright sky filled with clouds. A hummingbird feeder is hung nearby, attracting local wildlife.
Cottage in Gamboa
4.77 out of 5 average rating, 56 reviews

Gamboa rainforest lodging

Our restored canal zone home sits on a cul-de-sac in historic Gamboa. It is surrounded by trees and overlooks the town with Panama Canal and passing ships in the distance. An original Damon Kyllo mural adorns one large wall. You will love the balcony, high ceilings, artwork, breezes, and the cacophony of frogs, monkeys, and parrots. This is a great place for birdwatchers and a starting point for exploring the Panama Canal, Soberanía National Park, and the Chagres River.

Top Guest favourite
Apartment in Panamá
4.97 out of 5 average rating, 31 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Top Guest favourite
Loft in Panama City
5 out of 5 average rating, 16 reviews

Casco Viejo Dream Loft – Cozy & Central 1BR Apt

Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Casa Neuman",” this restored- colonial building and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Superhost
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Apartment in Panamá
4.93 out of 5 average rating, 136 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favourite
A modern dining area features a white table set for four, surrounded by stylish chairs. Large windows allow natural light to fill the space, revealing views of the city skyline. A sleek kitchen is visible in the background, showcasing a gas stove and granite countertops.
Apartment in Panamá
4.94 out of 5 average rating, 115 reviews

k*| Delightful 1 BR w/King Bed in Calle 50

Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Guest favourite
A well-lit bedroom features a spacious bed with light-colored bedding, complemented by decorative wall art. Natural light enters through large glass doors, which open to a small terrace with greenery. A cozy armchair is positioned nearby, enhancing the room's inviting atmosphere.
Condo in Santa Ana
4.96 out of 5 average rating, 28 reviews

King Bed, Creative Design Steps from Casco Viejo

Casco 114 is a stay created by travelers, for travelers. Located in the heart of Santa Ana, the creative district of Panama’s Casco viejo, it offers a king bed, full-size trundle, sofa bed, private terrace, washer/dryer, and unique decor. At PH Casco View: enjoy a saltwater pool, coworking space, stunning views of both the Old Town and the modern city, paid parking, and all the comforts for an unforgettable stay.

Superhost
Home in Brisas del Golf de Arraijan
4.77 out of 5 average rating, 30 reviews

Casa Esmeralda, Cozy for an Ideal Stay.

Casa Esmeralda is a spacious, comfortable, and cozy family home, ideal for families or groups looking for rest, privacy, and a great location. It features 3 bedrooms and 2 bathrooms, with bright, well-designed spaces created to make you feel at home from the very first moment. Located just 45 minutes from Panama City, in a quiet and easily accessible area, it’s perfect for combining relaxation and convenience.

Guest favourite
Apartment in Panamá
4.99 out of 5 average rating, 138 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Popular amenities for Santa Clara holiday rentals

  1. Airbnb
  2. Panama
  3. Distrito Arraijan
  4. Santa Clara