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House holiday rentals in Santa Cruz

Find and book unique houses on Airbnb

Top-rated house rentals in Santa Cruz

Guests agree: These houses are highly rated for location, cleanliness and more.

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Top Guest favourite
A spacious living area with a high ceiling supported by wooden beams features a modern kitchen and dining set. A comfortable sofa adorned with decorative cushions faces a dining table surrounded by chairs. Natural light illuminates the welcoming interior from large windows.
Home in Santa Cruz
5 out of 5 average rating, 14 reviews

The lodge door

Escape to the heart of the Colchagua Valley Enjoy a comfortable and quiet stay in our cabin for 4 people, located just 7 minutes from downtown Santa Cruz. Ideal for those looking to disconnect, perfect for exploring local cuisine, visiting boutique vineyards and discovering everything the Colchagua Valley has to offer. The cabin is new and runs on sustainable energy. Its peaceful surroundings and proximity to outstanding restaurants will make your experience unforgettable.

Top Guest favourite
A comfortable living area is depicted, featuring a dark brown sofa with decorative pillows and a wooden coffee table. A large television mounted on the wall displays a nature scene. Art pieces and family photos are arranged on the walls, enhancing the homely feel.
Home in Santa Cruz
4.97 out of 5 average rating, 190 reviews

Casa de Luz, fully equipped with parking.

Cozy retreat in the heart of the Colchagua Valley Discover a warm, bright space full of positive energy in Santa Cruz. A cozy equipped house, ideal for resting, reconnecting or enjoying the wonders of the valley: vineyards, history, gastronomy and nature. Here everything is designed to make you feel at home and that special touch that only a home with soul can offer. Wifi, full kitchen. Steps from the best vineyards Ideal for couples, families or solo getaways.

Top Guest favourite
A modern two-story house is showcased within a gated fence, featuring a blend of light and dark exterior finishes. Surrounding greenery is visible, enhancing the inviting entrance that includes a pathway lined with potted plants.
Home in Colchagua
5 out of 5 average rating, 31 reviews

Spectacular Santa Cruz house

Spectacular and luxurious house steps away from the Colchagua Casino, with all the amenities for a comfortable and safe stay. It is located in a cozy environment, within a quiet residential area, with green spaces, ideal for relaxing and enjoying the best places in downtown Santa Cruz, with easy access to the vineyards and their surroundings. The house has private parking, 3 bedrooms with double beds, a large and luxurious kitchen, gardens, and terraces.

Top Guest favourite
Home in Isla de Yáquil
5 out of 5 average rating, 14 reviews

Colchagua industrial loft among vineyards

Duerme en un loft entre viñedos de cabernet sauvignon en el valle de Colchagua Disfrutarás de un desayuno incluido en la tarifa con productos del campo. Puedes hacer cabalgatas en pareja con un guía que te acompaña Tienes bicicletas para recorrer En el loft cuentas con leña para usar la bosca o un fogón exterior Disfruta un quincho privado que con parrilla a carbón y un gran mesón Disfruta con caballos, ovejas, gallinas Checkin 24 horas

Superhost
A cozy bedroom is centered around a spacious bed adorned with a vibrant red quilt featuring floral patterns. Nightstands are positioned on either side, each topped with lamps. A piece of wall art depicting red flowers adds a touch of color to the light walls.
Home in Santa Cruz
4.73 out of 5 average rating, 15 reviews

Hostal del Vino (Wine Hostel) Master bedroom

The Hostal del Vino is a meeting place with the cultural and human roots of Colchagua. You can have a place to stay to connect with the peasant family of the Colchagua Valley, fair trade and enjoy the best artisanal wines in the area. Located in Santa Cruz. Just blocks from Plaza de Armas, the Colchagua Museum and restaurants. It has comfortable, bright and cozy rooms to ensure your rest and make your visit a pleasant stay.

Guest favourite
A comfortable living area features a light-colored sofa with decorative cushions, alongside a leather armchair. A wooden coffee table sits in front, and palm tree artwork decorates the wall. Large windows allow natural light to enter, and a view of the open kitchen is visible in the background.
Home in Santa Cruz
4.88 out of 5 average rating, 17 reviews

Casa Parrón

Have fun with the whole family in this stylish accommodation. Cozy house with an excellent location and ample parking Enjoy a comfortable and relaxing stay in this spacious house, ideal for families or groups of friends. It accommodates up to eight people. In addition, the house has ample parking and is in an excellent location, perfect for a quiet getaway or an extended stay. We look forward to seeing you!

Guest favourite
A two-story colonial-style house is featured, with a terracotta exterior and terracotta tile roof. A wooden gate marks the entrance, and a small tree is positioned next to the wall, adding a touch of greenery against the bright blue sky.
Home in Santa Cruz
4.86 out of 5 average rating, 203 reviews

Just like home...

Two-story colonial-style house, tiles, wooden gate closure. Decorated mostly with Raulí furniture. Cozy atmosphere, quiet neighborhood, quiet, ideal for resting away from noise. Close to Colchagua Casino, museum, plaza, bars, pub and restaurants. Uber contact for a known and trusted person. The house has private parking for two vehicles. Air conditioning, Wi-Fi, Netflix, and terrace for grilling.

Top Guest favourite
A covered porch area features a round glass table with two chairs, alongside a small grass patch with a set of six white chairs surrounding a table. The entrance is framed by a wooden door beneath a sloping roof, with a clear blue sky visible overhead.
Home in Santa Cruz
4.97 out of 5 average rating, 78 reviews

Comfortable and quiet house.

Relax with the whole family at this peaceful place to stay. Beautiful house located a short walk from downtown Santa Cruz, close to tourist attractions, a mini-market, a square, and the city entrance. It has an equipped kitchen and spaces suitable for rest. With 4 single beds, two bathrooms with a washing machine, a comfortable terrace with a grill, Wi-Fi, and TV.

Top Guest favourite
The exterior of the lodge is presented, featuring a modern design with large glass windows. The structure is supported by distinctive angled beams, surrounded by landscaped gardens with various plants and a gravel pathway. Open seating areas are visible on the spacious deck.
Home in Santa Cruz
4.97 out of 5 average rating, 252 reviews

LODGE ACACIA CAVEN

Lodge Acacia Caven Un espacio de lleno de tranquilidad y confort ,conectado con la naturaleza, a 4 km del centro de de ciudad de Santa Cruz, ubicado en parcela de agrado privada. Casa de 100 metros cuadrados con Hot Tub externo, Terraza, Fogón, estacionamiento propio, zona para asado y entrada independiente.

Superhost
A wooden porch is lined with large glass windows, allowing for ample natural light. A few wicker chairs are positioned near vibrant flowering plants, while a grassy area extends towards distant hills, enhancing the overall serene landscape.
Home in Pichidegua
4.81 out of 5 average rating, 48 reviews

Casa de Campo

In a house in the middle of a field of mandarins and avocados. It has panoramic views of the valley, which offer incredible sunsets. It has an en-suite room with views and the rest of the beds are in a cabin on site, in the common area. It is a house designed to be together and enjoy with family or friends.

Guest favourite
A tidy seating area features two comfortable armchairs and a small round table placed on a light rug. Natural light filters through a window, partially dressed with sheer curtains, while a piece of artwork adorns the wall.
Home in Santa Cruz
4.93 out of 5 average rating, 56 reviews

House in Santa Cruz, O'Higgins Region, Chile

Property in Los Viñedos sector, Santa Cruz. Excellent location, minutes from downtown and with access to services. It has a large living-dining room with natural light, 2 bedrooms, 1 bathroom, service patio and parking. Quality construction and well equipped.

Superhost
An outdoor dining area is illuminated by string lights, featuring a rustic picnic table surrounded by comfortable seating. A fire pit offers warmth and a focal point in the space, complemented by a large palm tree nearby and lush green grass.
Home in Santa Cruz
4.81 out of 5 average rating, 150 reviews

Comfortable house with swimmingpool

In the middle of the wineyards under the smoke of Santa Cruz in the Colchagua valley, you find this country home with big private yard and swimmingpool. It has a terrace with a bbq and also an outside oven. Close to all the wineyard like Vui Manet.

Popular amenities for Santa Cruz house rentals

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Avg. price$77 NZD$101 NZD$108 NZD$99 NZD$96 NZD$101 NZD$99 NZD$98 NZD$94 NZD$87 NZD$80 NZD$80 NZD
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Quick stats about house rentals in Santa Cruz

  • Total holiday rentals

    Explore 60 holiday rentals in Santa Cruz

  • Verified guest reviews

    Over 1,520 verified reviews to help you choose

  • Family-friendly holiday rentals

    30 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wi-Fi availability

    60 of Santa Cruz holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across Santa Cruz rentals

  • 4.8 Average rating

    Santa Cruz stays are highly rated by guests—averaging 4.8 out of 5!

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