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Holiday houses in Santa Cruz Island

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz Island

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Home in Puerto Ayora
5 out of 5 average rating, 56 reviews

Villa Náutica | Private Jacuzzi | Design

Perfecta para parejas, familias o amigos que buscan relajarse con estilo en Galápagos Villa Náutica es una elegante villa loft con jacuzzi privado, amplios espacios y un diseño náutico único inspirado en mis raíces suizas y galapagueñas Ubicada en un tranquilo barrio residencial, te permite disfrutar de la tranquilidad a solo 12 minutos caminando del centro de Puerto Ayora. Combina comodidad, autenticidad y el ambiente ideal para descubrir las islas y regresar a descansar en un acogedor refugio

Guest favourite
A modern living area is featured, including a dark sofa facing a wall-mounted television. Near the kitchen, a dining table with four chairs is visible, and various kitchen appliances are present. Natural light streams in through large windows, enhancing the space's openness.
Apartment in Puerto Ayora
4.97 out of 5 average rating, 100 reviews

Arena Suites | 2 Bedrooms • Residential Area | 2nd Floor

Disfruta Galápagos en este elegante departamento para 4 a 6 personas en zona residencial. Ofrece 2 hab con baño privado, agua caliente, secador de cabello, plancha, aire acondicionados y cortinas black out. Sala con 2 sofás cama, internet satelital y cocina equipada. Incluye shampoo y jabón biodegradable. Ubicación estratégica: a 2 cuadras Mini Market, farmacia y a 5 cuadras la Estación Charles Darwin, Parque Nacional Galápagos y el centro. ¡Paz y confort en el 2do piso con vista amigable!

Guest favourite
Apartment in Puerto Ayora
4.9 out of 5 average rating, 29 reviews

Eco Suite in Puerto Ayora, Wi-Fi / A/C, 20 steps from the sea

A suite inspired by the freshness of the ocean and the tranquility of the Galápagos. Located just 20 meters from the fishermen's pier in Puerto Ayora, close to cafés, laundromats, and the main restaurants in Puerto Ayora. Just a short walk from the accommodation, it is common to spot wildlife in their natural habitat, making each morning a unique experience if you want to take a walk and watch the sunrise from Pelican Bay Square. Cozy suite located just 20 steps from the ocean in Puerto.

Top Guest favourite
A bright living area features large windows allowing natural light to fill the space. A white sofa sits atop a dark rug, accompanied by a wooden coffee table and an armchair. The open kitchen is visible, showcasing wooden cabinetry and modern appliances.
Apartment in Puerto Ayora
4.95 out of 5 average rating, 185 reviews

Planet House Apt1: modern, spacious great location

Beautiful legally registered property, with partial ocean view and wonderful fresh breeze. Our apartment is located two blocks away from Charles Darwin Avenue. Guests can enjoy a leisurely walk to main attractions like the Charles Darwin Research Station and beach, great restaurants, cafés, shops, bike rental, dive shops, tour operators and more. Great options for guests seeking flexibility, comfort and value for money. The bedroom has AC, the living area benefits from a nice sea breeze.

Top Guest favourite
A spacious terrace features large windows providing abundant natural light and views of the surroundings. A colorful hammock is suspended between wooden posts, inviting relaxation. The tiled floor complements the wooden walls, creating a comfortable space suited for leisure and enjoyment.
Apartment in Puerto Ayora
4.97 out of 5 average rating, 104 reviews

Dominga Terrace/Pichincha Bank in front/Baltra av.

Ubicado en la terraza de uno de los edificios más altos de la isla, encontrarás una maravillosa vista todo el día. Muy fácil de localizar, en av. principal Baltra. Rodeado de restaurantes, tiendas y cajero automático Banco Pichincha cruzando la calle. A 4 cuadras de Terminal Terrestre y 3 cuadras de Mercado Municipal y parada de bus a zonas rurales. Privacidad en tu propia terraza abierta equipada con elementos para ejercitar, comedor y cocina con utensilios. Perfecto para reuniones.

Guest favourite
Apartment in Puerto Ayora
5 out of 5 average rating, 7 reviews

Modern Suite with Pool | Puerto Ayora

Disfruta de una estadía única en nuestras modernas suites en Puerto Ayora, diseñadas para ofrecer comodidad y tranquilidad. Relájate en nuestra piscina después de un día explorando las islas o disfruta la hermosa vista panorámica de puerto en nuestra terraza. ✔️ Ideal para parejas o viajeros que buscan comodidad y buena ubicación ✔️ Espacios limpios, nuevos y bien equipados ✔️ Ambiente tranquilo y seguro Te esperamos para que vivas la experiencia Galápagos con total comodidad.

Guest favourite
A welcoming living area features sleek furniture and a natural wood floor that reflects light. Two modern chairs are positioned around a minimalistic coffee table on a round woven rug. Large double doors open to a balcony, offering scenic views of the surroundings.
Apartment in Puerto Ayora
4.84 out of 5 average rating, 183 reviews

Oceanview Suite: Nest House

Welcome to our one-of-a-kind, bird’s nest-inspired suite in Puerto Ayora, Galapagos. Enjoy: ๏ Ocean views from your private balcony ๏ Cozy hanging bed for ultimate relaxation ๏ Artistic tree staircase ๏ Fully-equipped kitchen ๏ High-speed Wi-Fi (120 Mbps) and workspace ๏ Ventilated living space The bathroom is located just below the suite, offering added privacy. Stroll to nearby cafes, bakeries, and restaurants. Let us help you discover the best of the islands!

Guest favourite
A modern living space is presented with a comfortable sectional sofa and a coffee table at its center. The kitchen features sleek cabinetry, a refrigerator, and contemporary appliances. Natural light fills the area through a nearby window, enhancing the open floor plan.
Apartment in Puerto Ayora
4.97 out of 5 average rating, 62 reviews

Comfortable apartment in the heart of Puerto Ayora

Wake up to the essence of the islands: savor local organic coffee in your fully equipped kitchen. Our home blends the soul of Galápagos with modern comfort, using solar panels for the water systems and high-speed Starlink internet. Enjoy a plastic-free stay with purified water on tap, plus snorkeling gear and beach towels for your adventures. Relax at the BBQ area or use the on-site laundry (detergent included). Where sustainable living meets the gentle rhythm of island life

Top Guest favourite
The bright bedroom features two spacious beds with patterned bedding. Wooden beams add character to the ceiling while light fixtures create a warm ambiance. A large window allows natural light to fill the room, and a piece of art depicting a tree adorns one wall.
Bungalow in Puerto Ayora
4.9 out of 5 average rating, 315 reviews

Bright Garden Bungalow in a quiet neighborhood.

Sunshine filled, bright garden suite, next to the entrance to the Galapagos National Park and the Charles Darwin Station, and a few blocks away from some of the best restaurants, art galleries and bars in town. Located on the far end of one of Puerto Ayora's main streets, accessible to the road but removed enough to be isolated from the urban noise. An AC cools the suite when needed in the warmer months, and it’s screened windows are the alternative as well .

Top Guest favourite
Cabin in Santa Cruz
4.95 out of 5 average rating, 213 reviews

Casa Vikingo • Secluded Galápagos Highland Cabin

Perched in the Galapagos Highlands on the drier east side of Santa Cruz, Casa Vikingo is a tropical modern cabin designed for those seeking nature, architecture, and complete privacy. Surrounded by endemic forest and built from materials found on site, the cabin is immersed in one of the most unique landscapes in the archipelago. Wake up to views of the Pacific, soak in the private plunge tub, and experience a side of the Galápagos that few visitors ever.

Guest favourite
A charming exterior of a private accommodation is presented, featuring a rustic wooden door framed by lush greenery and colorful flowering plants. The natural stone pathway leads to the entrance, enhancing the inviting atmosphere of the serene outdoor space.
Home in Puerto Ayora
4.89 out of 5 average rating, 165 reviews

El Galapagueño House

Come! Enjoy the simplicity of this magical, quiet, centrally-located, and private place with your partner, family, or friends! An ideal place to rest after visiting the most extraordinary tourist sites of the Galapagos Islands!!! 🏡🐢🏞️🏝️☀️🐚 We look forward to seeing you! 15 minutes' walk to the pier 100 meters from the entrance to Tortuga Bay Beach 20 meters from the tennis court

Top Guest favourite
A spacious dining and living area features wooden floors and a combination of natural light and soft lighting. A round wooden table is surrounded by six chairs, while a cozy seating arrangement includes a plush couch. Decorative elements include a potted plant and unique glass brick wall.
Home in Puerto Ayora
4.91 out of 5 average rating, 101 reviews

Gps Villa

Perfect Villa for family or group of friends. Located in the best neighborhood on the island, very close to the main pier, restaurants, supermarkets, souvenirs. You can enjoy our villa and its facilities. We have a heated Jacuzzi with hydrojets, patio, solarium, living room, dining room, and kitchen.

Popular amenities for Santa Cruz Island holiday rentals

Frequently Asked Questions

  • Where is Santa Cruz Island located?

    Santa Cruz Island sits in the heart of the Galápagos Province, Ecuador, surrounded by the Pacific Ocean. It is part of the Galápagos Archipelago, known for distinct wildlife and protected natural habitats.

  • When is the best time to visit Santa Cruz Island?

    The climate on Santa Cruz Island is often comfortable year-round, with dry and warm conditions frequently suggested for outdoor activities. Many travelers appreciate the wildlife viewing opportunities available during alternating wet and dry seasons.

  • What are some things to do near Santa Cruz Island?

    Explore locally guided wildlife excursions, visit the Charles Darwin Research Station, and wander through traditional markets in nearby Puerto Ayora. Activities such as snorkeling, hiking, and bird spotting are frequently suggested for travelers.

  • How is the weather near Santa Cruz Island?

    Santa Cruz Island typically has mild tropical conditions, with warm temperatures and occasional rainfall distributed throughout the year. Visitors often experience comfortable days and cooler evenings, so packing for variable weather is suggested.