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Holiday houses in Santa Cruz

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Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A tranquil beachfront scene features several hammocks strung between palm trees on soft sand. Blue lounge chairs are positioned alongside the water, with gentle waves lapping at the shore under a clear sky.
Villa in Chame District
4.85 out of 5 average rating, 243 reviews

Surf Relax Play Pacific Ocean View Villa

White sand, surf-able waves, or just a comfortable chill vibe to enjoy the tropical weather of Panama. Playa Caracol is about an hour and 10 minutes drive from the city. This spacious, 2 bedroom, 2 bath villa with it's Pacific Ocean front location is the perfect place for you to enjoy an unforgettable family vacation. Walk out to the beach just steps from the villa, swim in the pool next to this villa or enjoy the resort pools and amenities. Or hike the nearby mountains with a local guide. PET

Top Guest favourite
A serene outdoor space features a large saltwater pool surrounded by multiple lounge chairs and red umbrellas. Lush greenery is visible in the background, providing a tropical setting under a bright blue sky. A hand holds a beverage in the foreground, adding depth to the scene.
Home in Costa Esmeralda
4.98 out of 5 average rating, 198 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Guest favourite
An aerial view reveals a stretch of coastline featuring sandy beaches with a mix of dark volcanic sand and vibrant turquoise water. Lush greenery lines the shore, complemented by residential areas visible in the background, creating a serene and inviting landscape.
Tiny home in San Carlos
4.8 out of 5 average rating, 127 reviews

Cozy beach cabin at Costa Esmeralda.

Cozy private community cabin on a triple space for up to three people located in Costa Esmeralda beach, over the Pacific ocean. Very quiet area with a 2,200 Square meter patio with trees and vegetation. Relax enjoying of the tropical sun, warm temperatures all year long and the ocean breeze. Only 8 minutes away by walk from the closest beach with warm waters and volcanic black sand. 10 minute drive to Coronado (Grocery Stores, restaurants, bakeries, movie theater, malls and much more)...

Top Guest favourite
The exterior of the cabin is depicted, featuring a stone wall and a metal roof. A manicured grass area surrounds the structure, with pine trees in the background against a bright blue sky, creating a serene environment.
Cabin in Chicá
4.94 out of 5 average rating, 280 reviews

Cabaña Horizonte by Casa Amaya

Relájate en esta escapada única y tranquila en Cabaña Horizonte. Casa Amaya es un complejo de 6 cabañas ubicado en Chicá de Chame, clima fresco entre 18 y 24 grados, donde podrás contactarte con la naturaleza y relajarte con tu pareja, amigos o familia. https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya Contamos con generador eléctrico en caso de apagón.

Guest favourite
The exterior of the house features a charming design with a red-roofed upper level and a welcoming terrace. A small pool is visible in the foreground, surrounded by lush greenery and natural rock formations. Cloudy skies create a serene atmosphere, enhancing the tranquil setting.
Home in El Nancito
4.94 out of 5 average rating, 31 reviews

Mountain Retreat: Peaceful & Private Escape

Escape to tranquility in our beautiful rural retreat near Laguna de San Carlos, Panama. Nestled on a private hectare of lush land, this cozy two-bedroom, two-bath house boasts an open terrace with breathtaking views of the San Carlos mountains. Whether basking in summer sun or enveloped in clouds during the rainy season, you’ll find peace and beauty here. Just a 30-minute drive to Coronado and the stunning beaches of Panama Oeste, it’s the perfect sanctuary for your getaway.

Guest favourite
Apartment in Las Lajas
5 out of 5 average rating, 5 reviews

Stylish & New, a short stroll away from the Beach

Welcome to your beachside escape at the Bambu Beach Haus! This brand-new modern duplex features a spacious king bed, stylish design, and all the comforts of home. Enjoy cooking in the fully equipped kitchen, relax on your private terrace or balcony, and take in the laid-back coastal vibe. Located in a resort-style community just a short stroll from the beach, you’ll also have access to a sparkling saltwater pool, jacuzzi, and cozy bohios—perfect for a relaxing getaway.

Top Guest favourite
Apartment in Chame, Panama
5 out of 5 average rating, 6 reviews

24 horas vista al Mar en Coronado

Relájate en este espacio tan tranquilo y elegante. Puedes caminar y llegar a la playa , caminas y puedes ir a comer rica cena o almuerzo con restaurantes muy cercanos, si deseas ir al gym tenemos todos los implementos, ir y disfrutar de la piscina , encantadora y grande para nadar, tenemos mesas de pipon,mesa de billar ,un área de recreación, y tienes espacio de trabajo, y vista refrescante al mar. contamos una habitación con cama Queen y un sofá cama .

Guest favourite
An outdoor patio space is presented with wooden chairs and a small table. Lush green grass extends towards the sandy beach, adorned with palm trees and sun loungers under thatched umbrellas, creating a calm coastal view.
Home in Chame
4.83 out of 5 average rating, 92 reviews

P/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath

This unique place has a style all its own, steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views and great on-site amenities. 1km of beach to offer you the best beach and surfing experience around.

Guest favourite
A bright living area features a comfortable sofa and a glass coffee table topped with a decorative plant. Bar stools are positioned at a kitchen counter, and a dining table accommodates seating. Large windows allow natural light to enhance the open space.
Condo in Nueva Gorgona
4.97 out of 5 average rating, 149 reviews

Espectacular Apto de Playa-PH Royal Palm-Gorgona

PRIMERA LINEA AL MAR CON BAJADA DIRECTA A LA PLAYA DESDE LAS PISCINAS DEL PH. Espectacular apartamento con vista al mar y cerro Chame, completamente amoblado para ser disfrutado por su familia. El PH tiene dos areas sociales con 4 piscinas, sauna, gimnasio, area de juegos para niños, area de barbacoa y 3 canchas multiusos. Del area social de PB se accede directamente al mar. SE ACEPTAN HASTA UNA (1) MASCOTA.

Superhost
A large swimming pool features clear blue water surrounded by lush palm trees. Comfortable lounge chairs are positioned nearby, offering a place to relax. The building in the background has multiple glass windows, providing a modern aesthetic to the tropical setting.
Apartment in San José
4.86 out of 5 average rating, 148 reviews

B11-Tropical beach paradise, 2R/2B condo, w/pool

Disconnect for a few days from the routine. Have fun with your partner or family in our apartment in Punta Barco Viejo, we have everything you need to be comfortable and have fun in one of the most exclusive areas of the area. We have everything nearby for your best convenience, restaurants, banks, supermarkets ... I´ll deliver a personalized 5 stars attention. Oh and of course, the BEACH 5min by car!

Top Guest favourite
Condo in Nueva Gorgona
4.95 out of 5 average rating, 22 reviews

Gorgeous Beachfront High Floor

Oceanfront escape! Bright 2BR/2BA condo with floor-to-ceiling windows, modern kitchen, and private balcony overlooking the turquoise sea. Relax in the spacious living area, enjoy stunning sunsets, or unwind in the stylish bedrooms with en-suite baths. Perfect for couples, families, or remote work with breathtaking views. Steps from the beach, dining & entertainment. Your dream coastal getaway awaits!

Top Guest favourite
A lounging chair is positioned beside a sparkling pool, accompanied by a small table. The table holds a glass of water and a bowl, with a book resting alongside. Lush greenery surrounds the area, adding a serene atmosphere.
Guesthouse in Nueva Gorgona
4.99 out of 5 average rating, 76 reviews

Beautiful Casita-Paradise in Panama, Nueva Gorgona

Fully furnished beautiful one bedroom casita is 500 sq. feet with an open living/dining concept. Fully equipped kitchen with new appliances and granite countertops. King size bed in bedroom and offers plenty of storage. Hide-a-bed in living room sleeps 2. **A great property for groups as we have two casitas and two studios on the property. Rent all four and have the place to yourself!

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz