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Holiday houses in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Townhouse in Chalco
4.98 out of 5 average rating, 62 reviews

Comfortable family home

Located in San Gregorio Cuautzingo, The accommodation is 42 km from the National Palace of Mexico The Museum of Fine Arts and the Post Office are 43 km from the apartment. The nearest airport is Benito Juárez International Airport, 40 km from the accommodation and guests benefit from free WiFi and private parking available on site. The apartment consists of 3 bedrooms, a living room, a fully equipped kitchen with a fridge and a coffee machine, and 2 bathrooms with a shower and a half bathroom.

LocationFamilyParking

Top Guest favourite
Home in Del Carmen
4.95 out of 5 average rating, 391 reviews

José Clemente Orozco House Coyoacán

Located in Coyoacán, typical Mexican neighborhood surrounded by markets, museums and historical buildings, a few blocks from Museu Frida Khalo, this house was the first studio for the painter and muralist José Clemente Orozco, who designed and build it between 1921 and 1923. All the bedrooms have their own bathroom and the main suite has a king-size bed, Smart TV and a terrace. It has a big and beautiful garden and a work space with its own terrace too. The garden is shared by 2 houses.

LocationValueNearby

Guest favourite
A well-maintained garden is surrounded by stone structures and lush greenery. Towering cypress trees frame the area, while flower beds add color to the landscape. Clear blue skies and soft clouds enhance the peaceful atmosphere of the outdoor space.
Cottage in Mexico City
5.0 out of 5 average rating, 22 reviews

Stay in a beautiful country estate.

Beautiful Hacienda Campestre in Milpa Alta, Mexico City, ideal for disconnecting from the hustle and bustle and being in contact with nature in a quiet and safe place. The property is located 25 minutes from the Xochimilco sports complex in the mountains. We are only 10 minutes from the magical neighborhood of San Pedro Atocpan. It has parking for several cars, a barbecue area, a beautiful campfire area, mini goals and an inflatable for young children. We are pet friendly.

LocationFamilyComfort

Guest favourite
Apartment in Roma Norte
5.0 out of 5 average rating, 12 reviews

Designer's Haven in Roma with Private Rooftop

Experience Mexico City like a local from this beautifully designed three-story home in the heart of Roma Norte. Walk to the city's best restaurants, cafés, boutiques, galleries, and parks. Accommodates up to 6 guests with 3 bedrooms, 3 full bathrooms, a spectacular private rooftop terrace, 4 Smart TVs, private elevator access, parking, and 24/7 security. A rare combination of space, privacy, design, and location in one of the city's most desirable neighborhoods.

LocationAmenitiesBathroom

Top Guest favourite
The building presents a modern design with a prominent use of green glass. The façade is enhanced by colorful window coverings, flanked by two parked cars. A clear sky serves as a backdrop, highlighting the structure's height and the surrounding area.
Apartment in Ciudad Nezahualcóyotl
4.98 out of 5 average rating, 255 reviews

Safety and Comfort in Edo.MEX

An apartment with great comfort, space, and security. It has a closed circuit, automatic main entrance door, alarm against theft, carbon monoxide and fire, excellent internet quality, and Smart TV. It has a lighting system with 3 shades: White, semi-warm and warm light, suitable for study and rest. The central stairs have handrails, non-slip, and sensor lighting. Fully-equipped kitchen and bathroom. Practical location with amenities available.

ValueFamilyCheck-in

Guest favourite
A cozy bedroom features a spacious bed with a soft grey headboard and decorative cushions. A sleek bedside lamp provides gentle illumination, while modern wooden cabinetry adds warmth to the space. A grey armchair is positioned nearby, complemented by delicate white flowers in the foreground.
Loft in Tlalpan
4.88 out of 5 average rating, 951 reviews

Punto Lofts Periférico Sur (South Peripheral Point Lofts)

Punto Lofts Periférico Sur is a modern concept with 18 fully equipped lofts, ideal for short or long stays. Each loft accommodates up to 3 people and has a queen size bed and sofa bed, offering comfort and rest. Enjoy 24/7 reception, digital key access, and high standards of cleanliness and safety. Located on Periférico Sur, opposite the Azteca Stadium, with easy access to hospitals, restaurants and shopping centers.

ValueLocationView

Top Guest favourite
Loft in Ayapango
5.0 out of 5 average rating, 21 reviews

Beautiful apartment with garden and volcano view

Escape to a dreamy retreat on the volcano route. Perfect for romantic getaways or family gatherings. Enjoy Stunning views of the volcanoes from your private garden, barbecue area and stone oven bring out the chef in you. Spacious and cozy space to relax and enjoy. Located in a picturesque village near Iztapopo National Park, this oasis is the ideal place to disconnect and reconnect with nature and your loved ones.

AccuracyOutdoor spacesNearby

Guest favourite
Cabin in Tlalmanalco de Velázquez
5.0 out of 5 average rating, 12 reviews

A little house near the volcanoes.

Village house near the volcanoes Enjoy a unique getaway in our cozy little house, ideal for 2 to 4 people. Perfect for families who want to spend a quiet and cozy weekend. Includes: Bed (King Size) + sofa bed (King Size) Kitchenette Mini fridge Microwave oven TV Wi-Fi Kitchen accessories Experience the local experience with comfort and charm, very close to the volcanoes.

LocationWi-FiNearby

Guest favourite
Apartment in Condesa
4.84 out of 5 average rating, 1871 reviews

Chic & Equipped Apt | Rooftop+Gym+B/Center+Lounge

This stylish apartment in the heart Roma Norte and Condesa offers the perfect setup for digital nomads—ultra-fast Wi-Fi, a sleek workspace, and steps from the trendiest cafés, restaurants, and nightlife. Enjoy top-tier amenities: a business center, a full gym, a game room, and a rooftop with stunning views. Stay productive, stay inspired, and experience CDMX like a local.

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Guest favourite
A welcoming entrance is displayed with a wooden door featuring decorative glass. Large windows with striped curtains allow natural light to brighten the space. Potted plants line the area, contributing to a serene ambiance. A small decorative item is hung next to the door.
Home in Tláhuac
5.0 out of 5 average rating, 49 reviews

Lovely house in the eastern area

Ideal accommodation for small groups, with a quiet and family-friendly atmosphere. Designed for comfortable stays with all the amenities. Close to the Nopalera Metro station, the ISSSTE General Hospital, the Tláhuac General Hospital, the Marista University, and Plaza Las Antenas.

LocationFamilyAccuracy

Top Guest favourite
Guesthouse in Xochimilco
5.0 out of 5 average rating, 51 reviews

Garden and beautiful house for events and stays

Camino Real Event Garden Disconnect from your concerns in this spacious and serene space. Ideal for all kinds of events, children's parties, meetings, weddings, corporate events, workshops, yoga courses or any other outdoor exercise or activity 🍃🌿🌤️

FamilyValueHospitality

Guest favourite
An outdoor terrace is presented with a wooden pergola, casting dynamic shadows across a spacious wooden dining table surrounded by benches. A kitchen area is visible with a modern design, and various potted plants are arranged along the perimeter, enhancing the natural ambiance.
Loft in Coyoacán
4.94 out of 5 average rating, 650 reviews

ECO-ROOF with terrace in the heart of Coyoacán

Nice and cozy room with a private balcony in the heart of Coyoacán, one of the most picturesque and traditional neighborhoods in Mexico City. Located a 5-minute walk from downtown Coyoacan, traditional restaurants, cafes, craft bazaars, and museums.

LocationValueIndoor spaces

Popular amenities for Santa Cruz holiday rentals