
Holiday houses in Santa Cruz
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Top-rated holiday rentals in Santa Cruz
Guests agree: these stays are highly rated for location, cleanliness and more.

Magical For 6 Rome, balcony, washing machine, desk
Enjoy a unique experience in the heart of North Rome, steps from Álvaro Obregón, the most iconic and lively avenue in the colony, covered by trees and full of terraces, galleries and local life. ✔ 🌳 Balcony with green views ✔ ☕️ Dozens of signature restaurants, specialty cafes, independent bookstores, designer boutiques and parks full of life, all on foot, without the need for uber. ✔ King Size Bed ✔ Washer dryer ✔ 2nd floor in a building without elevator Fell in love with the best of Mexico!
FamilyLocationNearby
4.95 out of 5 average rating, 19 reviews
Family Home in a Private, Quiet, and Safe Area.
Your home away from home in the State of Mexico! 🏡✨ Enjoy a peaceful, comfortable, and safe stay in this spacious house that accommodates 5 people. It features: 🛏️ 3 bedrooms, each with a double bed. 🛋️ 2 hallways, each with a sofa bed. 🚽 2.5 bathrooms (2 full bathrooms and one half-bath). 🍳 Fully equipped kitchen, Smart TV, and Wi-Fi. 🚗 Private, secure parking. Pets welcome (please check the rules regarding the 500 MXN surcharge). Total privacy for your trip! Pura vida! 🇨🇷🇲🇽
FamilyLocationSleep quality
4.98 out of 5 average rating, 63 reviews
José Clemente Orozco House Coyoacán
Located in Coyoacán, typical Mexican neighborhood surrounded by markets, museums and historical buildings, a few blocks from Museu Frida Khalo, this house was the first studio for the painter and muralist José Clemente Orozco, who designed and build it between 1921 and 1923. All the bedrooms have their own bathroom and the main suite has a king-size bed, Smart TV and a terrace. It has a big and beautiful garden and a work space with its own terrace too. The garden is shared by 2 houses.
FamilyLocationDecor
4.95 out of 5 average rating, 392 reviews
Kukun Homero Polanco
You’re about to discover your next stay! We’re thrilled to welcome you to our apartments. This building is not only in a prime location, but it also tells a story that celebrates contemporary Mexican art and culture. From handcrafted Talavera pieces made in Puebla to iconic quotes by renowned Mexican creatives like Octavio Paz and Alejandro González Iñárritu, every corner is designed to inspire you. Plus, you’ll get to enjoy one of the best views in the city.
LocationValueComfort
4.89 out of 5 average rating, 582 reviews
Safety and Comfort in Edo.MEX
An apartment with great comfort, space, and security. It has a closed circuit, automatic main entrance door, alarm against theft, carbon monoxide and fire, excellent internet quality, and Smart TV. It has a lighting system with 3 shades: White, semi-warm and warm light, suitable for study and rest. The central stairs have handrails, non-slip, and sensor lighting. Fully-equipped kitchen and bathroom. Practical location with amenities available.
LocationFamilyParking
4.98 out of 5 average rating, 256 reviews
Punto Lofts Periférico Sur (South Peripheral Point Lofts)
Punto Lofts Periférico Sur is a modern concept with 18 fully equipped lofts, ideal for short or long stays. Each loft accommodates up to 3 people and has a queen size bed and sofa bed, offering comfort and rest. Enjoy 24/7 reception, digital key access, and high standards of cleanliness and safety. Located on Periférico Sur, opposite the Azteca Stadium, with easy access to hospitals, restaurants and shopping centers.
LocationValueWi-Fi
4.88 out of 5 average rating, 956 reviews
A little house near the volcanoes.
Village house near the volcanoes Enjoy a unique getaway in our cozy little house, ideal for 2 to 4 people. Perfect for families who want to spend a quiet and cozy weekend. Includes: Bed (King Size) + sofa bed (King Size) Kitchenette Mini fridge Microwave oven TV Wi-Fi Kitchen accessories Experience the local experience with comfort and charm, very close to the volcanoes.
LocationSleep qualityAmenities
5.0 out of 5 average rating, 14 reviews
Logan’s house
Modern and spacious apartment just a 10-minute walk from the Autódromo Hnos. Rodríguez, 15 min from the GNP Forum and Palacio de los Deportes. 2 blocks from Zaragoza Metro and 5 minutes from AICM. It has a premium kitchen, fast Wi-Fi, Cablevision, Netflix, Disney+, Max and Prime Video. Quiet space with 2 bathrooms. Ideal for concerts, F1, business trips or rest.
LocationFamilyGetting around
4.94 out of 5 average rating, 109 reviews
Lovely house in the eastern area
Ideal accommodation for small groups, with a quiet and family-friendly atmosphere. Designed for comfortable stays with all the amenities. Close to the Nopalera Metro station, the ISSSTE General Hospital, the Tláhuac General Hospital, the Marista University, and Plaza Las Antenas.
LocationFamilyAmenities
5.0 out of 5 average rating, 49 reviews
Garden and beautiful house for events and stays
Camino Real Event Garden Disconnect from your concerns in this spacious and serene space. Ideal for all kinds of events, children's parties, meetings, weddings, corporate events, workshops, yoga courses or any other outdoor exercise or activity 🍃🌿🌤️
ValueLocationAmenities
5.0 out of 5 average rating, 52 reviews
HB Flat (2 BR) 15min Airport/10min Estadio GNP
Complete apartment 15 min from the airport, 10 min from the Foro Sol, Palacio de los Deportes and Autodromo Hermanos Rodriguez by car. 2 bedrooms with desk, bathroom, kitchen and living room - dining room.
ValueFamilyHospitality
4.93 out of 5 average rating, 553 reviews
Colonial house with garden in the center of Coyoacán
Luxury colonial house, 350 meters from the center of Coyoacan. The house has a garden and terrace. We strive to make your stay perfect. If your stay is long, we have cleaning service included.
LocationFamilyLaundry
4.96 out of 5 average rating, 168 reviewsPopular amenities for Santa Cruz holiday rentals
Other great holiday rentals in Santa Cruz

Stay in a beautiful country estate.
FamilyLocationComfort
5.0 out of 5 average rating, 22 reviews
Fresh and cozy rest.
LocationHospitalitySleep quality
4.83 out of 5 average rating, 18 reviews
Designer Penthouse | Huge Terrace | Pool & Gym
ValueFamilyCheck-in
4.96 out of 5 average rating, 47 reviews
Designer's Haven in Roma with Private Rooftop
LocationQuietSleep quality
5.0 out of 5 average rating, 14 reviews
Coapa Stay 2, Spacious, Secure Terrace for Enjoyment
LocationAccessAccuracy
4.96 out of 5 average rating, 25 reviews
Beautiful apartment with garden and volcano view
NearbyWi-FiOutdoor spaces
5.0 out of 5 average rating, 22 reviews
Luxury 2-story Condo
ValueLocationShared spaces
4.85 out of 5 average rating, 67 reviews
NEW Apt+Kitchen+Parking+TV+Laundry+Hot Water@CDMX
LocationFamilyAmenities
5.0 out of 5 average rating, 24 reviewsDestinations to explore
- The Angel of Independence
- Foro Sol
- Val'Quirico
- Reforma 222
- Palacio de los Deportes
- Aztec Stadium
- Autódromo Hermanos Rodríguez
- Basilica of Our Lady of Guadalupe
- World Trade Center Mexico City
- Auditorio Nacional
- Six Flags Mexico
- Monument To the Revolution
- Pyramids Of Teotihuacán
- Las Estacas Parque Natural
- Alameda Central
- Pepsi Center Wtc
- Palacio de Bellas Artes
- Los Dinamos
- Izta-Popo Zoquiapan National Park
- El Rollo Parque Acuático
- Constitution Square
- Jardines de México
- Citibanamex Center
- Bosque Geométrico





