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Holiday houses in Santa Cruz Tlaxcala

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz Tlaxcala

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Home in Santa Ursula Zimatepec
4.92 out of 5 average rating, 24 reviews

Casa Lozada – Spacious and beautiful home in Apizaco

Enjoy a comfortable, spacious and cozy home in Santa Úrsula that will make you feel at home. It has 3 bedrooms, 2.5 bathrooms, an equipped kitchen, terrace and garage for 2 cars. Strategic location: 10 minutes from downtown Apizaco, 20 minutes from Tlaxcala, 30 minutes from Huamantla, 25 minutes from the industrial corridor and 10 minutes from the Apizaco Sports Center. With easy access to transportation, supermarkets and schools. Ideal for relaxing and sharing unforgettable moments with family or friends

Guest favourite
The exterior entrance features a pathway bordered by greenery, leading to a modern façade with large windows. Plants are positioned for visual interest beside the pathway, while soft evening light enhances the welcoming appearance of the entrance.
Home in Apizaco
4.89 out of 5 average rating, 66 reviews

Complete House with 2 Bedrooms, Garden and Barbecue

Enjoy a comfortable and pleasant stay in this house with functional design and good taste. Perfect for families, couples or travelers, our house has everything you need to feel at home; comfortable rooms and hot water 24/7. Whether you are coming for work, tourism or visiting, you will find comfort and tranquility. 3 minutes from Chedraui, FEMSA, UATX, 7 minutes from the Apizaco Center, 8 from the Regional Hospital, 12 minutes from Ciudad Judicial, 20 from CIX I, and 30 minutes from La Malinche.

Guest favourite
A dining area is presented with a wooden table set for six, featuring glassware and plates. The space is illuminated by natural light from nearby windows, with a view into the kitchen area visible through an archway. Decorative elements and potted plants add to the ambiance.
Home in El Sabinal
4.96 out of 5 average rating, 123 reviews

"Casa Estela" is impeccable and comfortable.

Enjoy this beautiful house detailed in wood, well lit, ideal for 1 to 6 people, in a quiet and family area. Ground floor: garage for one car, living room, dining room, bar, full bathroom, equipped kitchen, patio with barbecue. Upper floor: master bedroom with 1 double bed, 1 comfortable sofa bed, 2 large closets, full bathroom, second bedroom with 1 double bed and spacious closet, plus a study for working. Just 15 minutes from downtown Tlaxcala and 5 minutes from a shopping mall.

Guest favourite
The open living area features a cozy green sofa and a marble coffee table. A small dining area is positioned beside the kitchen, which includes modern appliances. Natural light enters through large windows, while a spiral staircase leads to the upper level.
Loft in Santa Isabel Tetlatlauca
4.89 out of 5 average rating, 176 reviews

Piacere loft Val'Quirico. Bed, Jacuzzi & Coffee

Lotf Piacere, cuenta con un diseño único y con jacuzzi privado. Además (te rentamos auto para 4 personas) Este espacio se encuentra en el corazón de Val' Quirico, con una ubicación de 10, podrás salir y a unos cuantos pasos encontrar encantadores restaurantes, cafés, tiendas, bares, etc. En casos especiales te rentamos un auto para cuatro personas y conozcas la región a 20/30 minutos prehispánica como Cacaxtla, Xochitecalt y Tlaxcala capital

Top Guest favourite
A spacious sleeping area features a wooden four-poster bed with soft gray bedding. Natural light fills the room through large windows, framed by minimalistic light fixtures. A small table and chair are positioned beside the window, offering a serene view of the surrounding greenery.
Loft in Santa Agueda
4.99 out of 5 average rating, 137 reviews

Exclusive Penthouse, Val`Quirico

Perfect romantic escape for couples or solo travellers looking to unwind and relax. The private penthouse apartment is just a five minute walk away from the heart of Val’Quirico, includes free parking and a fully equipped kitchen. The private terrace is perfect for romantic dinners, star gazing and has amazing views of the Malinche mountain where the sunrises. An ideal space to recharge, celebrate love and enjoy an unforgettable experience.

Guest favourite
Cottage in Santa Cruz Tlaxcala
4.92 out of 5 average rating, 38 reviews

Spectacular Ranch 5 minutes from Trinidad IMSS

Bring the whole family to this fantastic place, enjoy the tranquility of nature, without leaving aside the fun both outside and inside, with the bar, pool table or movie night! Relax at this ranch located in the municipality of Santa Cruz Tlaxcala. Enjoy the views from the hillside, walk around the property, or visit the La Trinidad Holiday Center. At night, immerse yourself in the incredible views of the galaxy in the open field.

Guest favourite
A decorative stone fountain features a multi-tiered design, with flowing water cascading down. Surrounding the fountain are vibrant red poinsettias in black planters, creating a welcoming focal point in the outdoor space.
Home in Apizaco Centro
4.94 out of 5 average rating, 211 reviews

AMAZING "CASA CARMELA" in the center of Apizaco

THIS SPACE FOLLOWS AIRBNB'S ADVANCED CLEANING PROTOCOL. Cozy and wonderful 1-story house, located in downtown Apizaco. Excellent location a few blocks from restaurants, bars, convenience stores, cinema, among others. The house has excellent essential services (Internet, Netflix), as well as a garage (5.0 meters long) for a small or medium-sized sedan or SUV. We accept small or medium-sized pets; large pets with prior approval.

Superhost
An inviting living area features comfortable leather sofas arranged around a coffee table. A dining table with metal chairs is placed in proximity, complemented by a decorative centerpiece. Large windows allow natural light to fill the space, with textured wall panels adding visual interest.
Home in Tlaxcala
4.83 out of 5 average rating, 23 reviews

Beautiful Private Residential House

Casa Ilallali is a beautiful and spacious 3-story house located within a gated community that has all the basic services such as hot water, kitchen, laundry area, private parking for two cars, closed circuit TV, 6 very comfortable beds and a beautiful Roof Garden ready to prepare your carnita asada and observe the incredible landscape that Tlaxcala offers with a Cuatlapanga and the Malinche in the background.

Guest favourite
An open living space features a modern dining area with a glass table and dark chairs. A cozy seating area includes a gray sofa, while a mounted television is positioned against a textured accent wall. Bright artwork and plants add lively touches to the environment.
Apartment in Apetatitlán
4.93 out of 5 average rating, 68 reviews

Comfortable apartment in Tlaxcala

Excellent cozy apartment in a quiet area. Enjoy a good space equipped with all the amenities, ideal for family vacations or business trips. Discover it and feel at home. Located 5.4 km from the historic center (12 min), 2.8 km from the Altiplano Zoo and Gran Patio Tlaxcala (6 min). Nearby you will have convenience stores and food outlets. Quiet area.

Guest favourite
A living area features comfortable black sofas arranged around a coffee table. Natural light fills the space, highlighting the minimalist decor. A doorway leads to a kitchen area, with cabinetry and an organized layout visible in the background.
Apartment in San Miguel Contla
4.8 out of 5 average rating, 49 reviews

Comfortable apartment with an excellent view

Cozy, quiet and luxurious apartment, ideal for family and friends who come to visit "located 3 minutes from the Trinidad Vacation Center, 5 minutes from Apizaco Centro, 15 minutes at the foot of Volcán la Malinche and 20 minutes from Huamantla" Great view and location! Don't think about it and take advantage of your stay !

Guest favourite
Loft in Tlaxcala
4.94 out of 5 average rating, 264 reviews

Beautiful Loft in Valquirico, Lofts Frontana.

A nice loft where you can continue to enjoy the beauty of Val'Quirico just by opening its balconies and listening to music and sitting in the dining room with a glass of wine. Opening its windows in the mornings is magical because you see the rooftops from bed. A place made to enjoy.

Guest favourite
Holiday home in La Loma Xicohténcatl
4.83 out of 5 average rating, 170 reviews

Nice apartment near downtown Tlaxcala.

The apartment is very comfortable for families as it has everything you need for a pleasant stay. It is on the ground floor and very close to downtown Tlaxcala.

Popular amenities for Santa Cruz Tlaxcala holiday rentals

  1. Airbnb
  2. Mexico
  3. Tlaxcala
  4. Santa Cruz Tlaxcala