
Holiday houses in Santa María
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Santa María
Guests agree: these stays are highly rated for location, cleanliness and more.

Beach House-Amazing Pool & Jacuzzi - Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Country House Like in the City / La Casita
Casa fresca, con árboles y naturaleza. Áreas amplias para descansar. Ubicación céntrica, cerca de malls, restaurantes, estación de buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Ahora, Chitré, tiene un problema con el agua: no está potable; tenemos 50% de lo habitual, a veces estamos sin agua por algunas horas. Por favor, consulten antes de reserar.

Country House in Olá, rivers, waterfalls, Los Picachos
Finca La Terapia lives up to its name, nestled among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day-to-day life of the city. It has 42 private hectares to explore nature. The district of Olá is characterized by having the most beautiful natural landscapes among which we can mention, Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the Finca.

Aqeel cabin in the nature
Relax at this unique and tranquil getaway surrounded by nature. If you're lucky, you may wake up to see white-faced capuchins from your bedroom window and spot an abundance of birds, such as the crested oropendola or a toucan. The property offers river access with a sandy, beach-like area, and there is a 1 km walking trail alongside the river. With satellite high-speed internet access, you'll stay connected, though the river and sandy area may not be accessible during rainy days.

Mountain retreat
Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Country House with Pool in La Enea de Guararé
Far from the capital city, come to enjoy Panamanian folklore in a rustic but cozy space living a native experience. Lounge in the pool or lounge in a hammock, breathe fresh air, close to the ocean, surrounded by wide, natural gardens for a good walk. Close to the Puerto de Guararé where you will enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian chickens.

Sun Cabin at Finca Namuiki by the River
Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

k* Casa Matilde | 2BR Santa Fe Retreat by River
Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

Comfortable, fenced and safe house.
Enjoy the simplicity of this spacious, quiet and centrally located place at Casa las Hamacas. You can enjoy the pleasant Penonomeño climate. A place close to everything, shopping malls, schools, hospital, mountains, rivers and beaches. Both rooms feature A/C to ensure your rest. A few minutes away from the Pan-American Highway.

Colonial House in Parita
Discover the charm of Parita from a comfortable and spacious home, perfect for large groups. Located in the picturesque and peaceful town of Parita, in the Herrera Province, just 12 minutes from Chitré, this spacious home is the ideal place to immerse yourself in the history and culture of a historic colonial-era town.

Little home near to the beach -Las Tablas
10 min drive- Las Tablas Get away from it all when you stay under the stars. A room very close to the sea, with an open kitchen that will allow you to disconnect and enjoy the view and nature in Las Tablas. You can plan to visit nearby beaches or take a walk through Pedasí, 30 minutes from Las Tablas.

Spacious house in Villa de los Santos
Comfortable family accommodation in La Villa de Los Santos, with Wi-Fi, A/C, equipped kitchen, patio and parking. Located near supermarkets and plazas. Just 15 minutes from El Rompió y Monagre, 45 minutes from Isla Iguana and 1h 30 minutes from Playa Venao.
Popular amenities for Santa María holiday rentals
Other great holiday rentals in Santa María

Mountain Retreat: Peaceful & Private Escape

Peaceful home w/ spacious living & office area

The Emberá ※ Unique experience in an indigenous hut

El Refugio: Nature Escape in Chitre

Casa Julius | Elegant Villa with Sea view & Pool

Cabin with river view

Furnished apartment in Aguadulce

Central Chitre Home: Walk to Union Park
Destinations to explore
- Panama City Holiday rentals
- San José Holiday rentals
- Puerto Viejo de Talamanca Holiday rentals
- Jaco Holiday rentals
- Uvita Holiday rentals
- Boquete Holiday rentals
- Quepos Holiday rentals
- Playa Blanca Holiday rentals
- Ancón Holiday rentals
- Bahía Ballena Holiday rentals
- Limon Holiday rentals
- Valle de Antón Holiday rentals




