Villa holiday rentals in Isle of Palms
Find and book unique villas on Airbnb
Top-rated villa rentals in Isle of Palms
Guests agree: These villas are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Isle of Palms villa rentals
Private villa rentals
Villa in Saint Helena Island
4.99 out of 5 average rating, 83 reviewsSandy Toes Condos
Villa in Seabrook Island
4.84 out of 5 average rating, 61 reviewsPrivate island villa with luxury resort amenities!
Villa in Seabrook Island
5.0 out of 5 average rating, 15 reviewsClose to beach, pools, golf&tennis +Amenity Card*
Villa in Kiawah Island
4.96 out of 5 average rating, 98 reviewsSpacious new 2BR Villa across beach near Sanctuary
Villa in Kiawah Island
4.96 out of 5 average rating, 89 reviewsLagoon view villa with office, easy walk to beach!
Villa in Seabrook Island
4.86 out of 5 average rating, 37 reviewsSeabrook Golf View Villa: Pickleball, Pool, Bike
Villa in Edisto Island
4.74 out of 5 average rating, 54 reviewsLoft-e-Lagoon *No Cleaning Fee*
Villa in Seabrook Island
4.91 out of 5 average rating, 33 reviewsUpscale Villa, Amenity Included! Dog Friendly
Luxury villa rentals
Villa in Seabrook Island
4.93 out of 5 average rating, 14 reviewsLuxury Seabrook Isl Beach Condo
Villa in Kiawah Island
5.0 out of 5 average rating, 26 reviewsOcean Front! Beach is steps away. Clean and Crisp!
Villa in Kiawah Island
5.0 out of 5 average rating, 3 reviewsIncredible, completely renovated oceanfront villa
Villa in Seabrook Island
Seaside Therapy - An iTrip Vacations Home
Villa in Kiawah Island
4.94 out of 5 average rating, 17 reviewsOceanfront Windswept Villa
Villa in Isle of Palms
5.0 out of 5 average rating, 5 reviewsOceanfront Villa in Wild Dunes! Community Pool!
Villa in Mount Pleasant
4.94 out of 5 average rating, 16 reviewsCoastal 3BR in Old Village with patio & yard
Villa in Kiawah Island
4.89 out of 5 average rating, 18 reviewsSpacious Penthouse 3BR 3Bath Villa with Ocean View
Villa rentals with a pool
Villa in Folly Beach
4.82 out of 5 average rating, 62 reviewsComfy Cool-Pool-River Views-Beautifully Updated
Villa in Seabrook Island
4.95 out of 5 average rating, 60 reviewsBeautiful and Spacious 2 Bedroom Courtside Villa!
Villa in Beaufort County
4.88 out of 5 average rating, 8 reviewsJohn Fripp Villa- Pool Views, Beach Access
Villa in Isle of Palms
4.78 out of 5 average rating, 27 reviewsBeachfront IOP Villa with Outdoor Pool. Remodeled!
Villa in Isle Of Palms
4.78 out of 5 average rating, 40 reviews7C Seagrove - Sweetgrass
Villa in Isle of Palms
4.77 out of 5 average rating, 47 reviewsUpdated 2BR | Balcony | Pool | Dock
Villa in Fripp Island
5.0 out of 5 average rating, 5 reviews338 Capt John Fripp Villa W/Cart, Cards Available!
Villa in Seabrook Island
5.0 out of 5 average rating, 5 reviewsStunning Water Views Renovated Modern Oasis
Quick stats about villa rentals in Isle of Palms
Total rentals
70 properties
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Rentals with a pool
70 properties have a pool
Family-friendly rentals
60 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
$277 NZD before taxes and fees
Destinations to explore
- Savannah Holiday rentals
- Hilton Head Island Holiday rentals
- Kiawah Island Holiday rentals
- North Myrtle Beach Holiday rentals
- Tybee Island Holiday rentals
- Folly Beach Holiday rentals
- Surfside Beach Holiday rentals
- Mount Pleasant Holiday rentals
- Hilton Head Holiday rentals
- Atlanta Holiday rentals
- Charleston Holiday rentals
- Myrtle Beach Holiday rentals
- Villa rentals United States
- Villa rentals Myrtle Beach
- Villa rentals Charleston
- Villa rentals Savannah
- Villa rentals South Carolina
- Rentals with a kayak Isle of Palms
- Apartment rentals Isle of Palms
- Beachfront rentals Isle of Palms
- Condo rentals Isle of Palms
- Monthly Rentals Isle of Palms
- Rentals with a fireplace Isle of Palms
- House rentals Isle of Palms
- Rentals with a fire pit Isle of Palms
- Luxury rentals Isle of Palms
- Rentals with a washing machine and dryer Isle of Palms
- Rentals with a hot tub Isle of Palms
- Rentals with beach access Isle of Palms
- Rentals with a patio Isle of Palms
- Beach condo rentals Isle of Palms
- Rentals with outdoor seating Isle of Palms
- Fitness-friendly rentals Isle of Palms
- Kid-friendly rentals Isle of Palms
- Pet-friendly rentals Isle of Palms
- Rentals with pools Isle of Palms
- Waterfront rentals Isle of Palms
- Family-friendly rentals Isle of Palms
- Wheelchair accessible rentals Isle of Palms
- Villa rentals Charleston County
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