Holiday houses in Byron

4.93 out of 5 average rating, 162 reviews

Woodland Retreat, Full private walkout lower level

Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

5 out of 5 average rating, 45 reviews

New! MN Comforts The Heart 4Bd/2Bth, 12min to Mayo

Welcome to MN Comforts The Heart! Are you here for work or leisure, or want to feel comforted after a Mayo appts? 12 min to Mayo Clinic, Wifi, work-station, ROKU/Smart TVs, and a fireplace in the family room. We offer a 2nd home feel. Near stores. Split-level, chill, and quiet, thoughtfully designed to cater to your needs, ensuring a comfortable, enjoyable stay. A blend of traditional & modern styling in a tranquil home, with fun opportunities for family & friends. Partially fenced backyard.

4.97 out of 5 average rating, 118 reviews

Home in Kasson

Home Sweet Minnesota

A few days or a few weeks away from home? Let us provide a comfortable and cozy get away in this turn of the century, two story home. Located in a quiet neighborhood with off-street parking, this property boasts large rooms, original hardwood floors and woodwork, a full kitchen, and laundry. The large, fenced in backyard, complete with playground and sandbox, makes this a child friendly space. The front porch and back patio provide outdoor room to grill, picnic, or just relax in a lawn chair.

4.96 out of 5 average rating, 104 reviews

Home in Stewartville

Stewartville Charmer 4/2 by Park, 8 min to airport

Beautiful 1913 4 bedroom 2 bath home with original woodwork just 12 miles (about 15 -20 minutes) from the Mayo Clinic and less than 10 minutes to the airport. The home backs up to a park with both trails and playground equipment. There is on and off street parking and from Nov 15 - March 15 includes 1 garage space. Fully furnished home with complete kitchen, bedding and towels. Main floor bathroom has a seated shower with handheld. I will provide a Mayo Clinic parking pass upon request.

4.92 out of 5 average rating, 248 reviews

Home Calls the Heart- 10min to Mayo

1/2 block from HWY 52, serene and peaceful split level home. 10 min to Mayo Clinic & St. Mary's Hospital. Fully furnished, convenient and ideal for families and professionals for the home away from home feel. Luxury Sheets & Posturepedic beds. Reasonable Mall of America drive. Fully equipped with various kitchen appliances and utensils. Minutes to parks, groceries, Walmart, Target etc. Wifi, Roku Smart TV & cable. Phone call away if you have any issues while staying at our charming home.

4.93 out of 5 average rating, 160 reviews

Home for the Traveler, a walk to St. Mary's

This place is located near the heart of Rochester, within blocks of St. Mary's hospital, very peaceful, cozy and private. A lower-level unit in an older home, plenty of windows and light, and includes a gorgeous bedroom with a fireplace, a full kitchen, a reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, coffee shops, and the walking/biking trail system. There is also Wi-Fi, laundry, and parking on-site.

4.87 out of 5 average rating, 343 reviews

Mayo Downtown's Prairie Home Retreat

Nestled in a serene corner, this home offers a perfect blend of tranquility and accessibility; being near the Mayo campus and Rochester's key attractions. Enjoy comfortable beds, a well-appointed kitchen, and a fenced yard with patio gardens. It's an excellent spot for family bonding, featuring three smart TVs, rapid Wi-Fi, and a variety of indoor and outdoor entertainment options. We strive to accommodate flexible check-in/check-out arrangements whenever feasible. Rollator accessible.

4.97 out of 5 average rating, 242 reviews

Restful sanctuary close to Mayo Clinic

This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

4.97 out of 5 average rating, 227 reviews

Guesthouse in Rochester

Hygge House | A Cozy Guesthouse

The Hygge (pronounced hyoo·guh) House is a tiny taste of Scandinavia in Southeastern Minnesota. What is Hygge? In short, it's a Scandinavian way of living that focuses on hunkering down and creating a safe, comforting and warm place to while away. My husband and I hand built the Hygge House with your comfort in mind. We love being cozy and having space to spend together so when the opportunity arose to renovate our studio, we wanted to share it!

Superhost

4.87 out of 5 average rating, 223 reviews

SALE: Remodeled retreat near Mayo Clinic

• Enhanced cleaning protocols due to COVID • Fully renovated apartment in summer 2018 • 650 square feet • Upstairs apartment in quiet 4plex • Free off-street parking • 5 blocks north of Mayo Clinic • Walk-in tiled shower • Queen bed • Full kitchen with gas stove (new 5/16/19) • Reclining leather loveseat • 43" Smart TV with DirecTV/cable • High-speed WiFI — 300 MBPS • Shared laundry in the basement • Huge windows for tons of natural light

Superhost

4.83 out of 5 average rating, 506 reviews

Cozy home next to Mayo Clinic & historic parks!

Cozy single level 2 bedroom, 1 bath. Fully furnished kitchen with TV, WiFi, and smart lock. It’s a 1.6 miles to Mayo Clinic. Walking distance to Historic Quarry Hill Park and Silver Lake Park. City bus line to Mayo Clinic 1/2 block away. Newly remodeled bathroom with full linen and toiletries. Quiet neighborhood, with full driveway parking. We also have a baby gate for the stairs. Enjoy your next home away from home !

4.98 out of 5 average rating, 150 reviews

Condo in Rochester

Cedar Loft is a tranquil retreat

If you are looking for a quiet retreat w/private entrance outside the city, you are home. Trees are outside every window with palpable serenity yet is still an easy ten-minute drive to downtown Rochester. This is a family-friendly place with crib and changing table. This is not a party house. It has a kitchenette so we will provide information to restaurants and grocery stores within 5 minutes.

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Other great holiday rentals in Byron

4.95 out of 5 average rating, 415 reviews

Magical Nest

MicheleRating, 5 stars1 week ago

We love staying at the Magical Nest. It is beautiful, peaceful and comfortable. Greg and Yvonne are perfect hosts.

4.87 out of 5 average rating, 60 reviews

Relaxing, comfortable, 3 bedroom home near Mayo!

PatJesRating, 5 stars1 month ago

We stayed while our daughter was at Mayo for a medical procedure. Super quick and easy to get to hospital and clinics. Very close to groceries and restaurants. Hosts were always proactive and very accommodating. Very spacious! Perfect for family with children. Very clean! Will stay again if available when we return for follow-up visits.

4.84 out of 5 average rating, 19 reviews

Home in Byron

Cozy Duplex Unit 10 minutes to Mayo Clinic

MarkRating, 5 stars7 months ago

Great place to stay! Would definitely stay there again!

4.98 out of 5 average rating, 120 reviews

Cozy home 1 bedroom & bathroom, w/no cleaning fee

SherryRating, 5 stars2 days ago

This was a great place to stay. Jacqueline was very responsive to any email and was very welcoming. I had to leave very early and she was up to say thank you and goodbye. Lovely home and yard and absolutely wonderful and gracious host and hostess.

5 out of 5 average rating, 7 reviews

The Wander Inn/ Cat 40+ yrs in Healthcare

LanaRating, 5 stars2 weeks ago

I believe Cat has one of the most affordable prices in Rochester. Cat greeted me at the door, was super kind, and anytime I texted, she responded within 30 minutes if not sooner. Cat's location is conveniently less than 15 minutes away from Mayo Clinic as well! The place was identical to what was pictured, and I was very satisfied with Cat's hospitality. I will make note that the bed in the bedroom is firm, so for my preference I do prefer softer beds.

4.77 out of 5 average rating, 26 reviews

Cute Rochester House

EricRating, 5 stars2 days ago

Very nice space a short drive away from downtown Rochester.

4.92 out of 5 average rating, 107 reviews

Sun-Lit Private Room near Serene Douglas Trail

TodRating, 5 stars9 months ago

Really wonderful hosts and beautiful family. Lovely home, & very peaceful/comfortable room. We feel very fortunate to have had the opportunity to stay. Thank you, Tod & Tess