
Holiday houses in Byron
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Top-rated holiday rentals in Byron
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The BEST Stay in Town: See Pics+Reviews to Believe
One level living/no stair. 2 bedrooms with 3 beds One-side of a duplex home: 1,200 Squarefeet w/ your own private entry, parking, laundry, kitchen.. 2.5 miles to Mayo, Target, Hyvee, gas stations...Fully furnished home. Smart TV & Fridge w/ Superfast internet & NetFlix included. Easy self-check-in keypad. A few blocks to the bus stop. Modern/spacious interior. Fully equipped kitchen w/ dishwasher, pots, pans, and washer/dryer at no additional cost. Fireplace & private deck. 3 parking spaces

Woodland Retreat, Full private walkout lower level
Peaceful retreat down gravel driveway 15 min from Mayo Clinic. Enjoy your own apartment with private backyard walkout entrance to the lower level of our home. You will have a bedroom, living area, kitchenette with mini fridge, microwave and toaster oven (no conventional stove/oven), bathroom w/ tub & shower, pingpong table, laundry, and patio with fire ring. You may hear piano music weekday afternoons, since I give lessons (usually 3-6 pm; a bit earlier in summer) NEW HEATED FLOORS w/thermostat

Home Calls the Heart- 10min to Mayo
1/2 block from HWY 52, serene and peaceful split level home. 10 min to Mayo Clinic & St. Mary's Hospital. Fully furnished, convenient and ideal for families & professionals for the home away from home feel. Luxury Sheets and Posturepedic . Fully equipped with various kitchen appliances and utensils. Minutes to parks, groceries, shopping etc. Wifi, Roku Smart TV & cable. Phone call away if you have any issues while staying at our charming home. No pets due to Mayo Clinic guests’ allergies.

Euro House, Bright! Near Mayo-Single Family Home
Welcome to your home away from home! This private, single-family home was thoughtfully designed and is located in a quiet area just 5 minutes (0.9 miles) from the Mayo Clinic. Step into a master gardener’s dream—a beautifully landscaped yard filled with native plants and outdoor seating, perfect for relaxing after a long day. 2 Queen Bedrooms, 2 Full Bathrooms, modern finishes throughout, Super clean and pet-free. Off-street parking, Washer & dryer, Wi-Fi, Smart TVs & Fully stocked kitchen.

Home for the Traveler, a walk to St. Mary's
This place is located near the heart of Rochester, within blocks of St. Mary's hospital, very peaceful, cozy and private. A lower-level unit in an older home, plenty of windows and light, and includes a gorgeous bedroom with a fireplace, a full kitchen, a reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, coffee shops, and the walking/biking trail system. There is also Wi-Fi, laundry, and parking on-site.

The Little House | 1 mi from downtown, Love Pets!
The Little House is the perfect place of you're looking for something Cozy, stylish, and close to everything that you need. This home was a fun renovation project for my husband and I. It's located in the family friendly Sunnyside Addition neighborhood and we've worked hard to make sure you have everything you need during your stay. This home has a beautiful fully fenced in yard with a neighborhood feel while still being less than a 5 minute drive from Downtown & Mayo Clinic Campuses!

Oasis - Comfort & Serenity (Full house near Mayo)
*Discount for extended stays* Seeking a peaceful respite near Mayo Clinic in Rochester, MN? Look no further than "Oasis"–your ultimate home away from home. We offer 5 beds, 2 baths, & can accommodate up to 8 guests. Recharge in the workout & yoga meditation room, stay connected in the office area, & explore Rochester's attractions. Your dedicated host Peggy, a Mayo employee, will ensure a seamless/enjoyable stay. Book now & experience the perfect blend of comfort & serenity at Oasis.

Restful sanctuary close to Mayo Clinic
This cozy space has private, self-entrance with off-street parking at no cost...a mere 2.5 miles or 10 minute drive to the Mayo Clinic downtown. Located in a quiet neighborhood in northwest Rochester. Easy access to highways, grocery store, coffee shop, Target, restaurants and biking/walking trail. Completely furnished with linens, hair-dryer, Netflix and Hulu, Smart TV and Wi-fi....and a Keurig Coffee maker with enough coffee pods to get you started. Truly, a home away from home!

Spacious Modern Home Near Mayo, St. Mary's Campus
- 5 min walk to Mayo Clinic, St. Mary’s campus - 3 bedrooms, 3 bathrooms, and a loft - unique design with vaulted ceiling and skylights in the style of Frank Lloyd Wright, one of its kind in the whole neighborhood - two-car garage + another dedicated parking space outside - walkable and safe family-friendly neighborhood close to downtown and all amenities - outside front and back patios - fusball play table - dedicated workspace - high speed wifi - Apple TVs - washer and dryer

Entire Boutique Home Kutzky Park ★ Walk to Mayo ★
Welcome to Asfar house! Expertly designed and centrally-located in a desirable Kutzky Park neighborhood, walking distance to Mayo Clinic, restaurants and shops. Whether you are relocating or visiting Rochester, this house will be sure to impress. Blasting fast WIFI, 3 relaxing bedrooms & a fully equipped kitchen. A perfect retreat to enjoy the coffee bar, read, watch a Netflix episode, play and relax. Enjoy the perfect shower, conveniently adjoined with free washer and dryer.

Cottonwood Cottage
This beautiful 3 bedroom home is just 12 blocks from Mayo. It has plenty of space for your family. It has a nice kitchen with quartz counters. It also has a large living room with game corner, work area and Roku TV for all your streaming services. The home is located on the end of a quiet street and access to Rochester's vast walking/biking trails starts right out the front door. There is also a back patio with seating and a gas grill.

St. Augustine’s Family Home ❤️ GARAGE!!
Wonderful clean, newer home located in the fast growing NW Rochester. The home is the perfect set up for large families. Recliner! 2 bedrooms and 2 bath located upstairs on main level, 2 bedroom and bath located downstairs.. The home is well equipped, comfortable, and clean. Smart Tv and fast WiFi!!! 2 car garage and snow service included!! Restaurants, playgrounds, salons, bars, breweries, movie theatre, and shopping minutes away!!
Popular amenities for Byron holiday rentals
Other great holiday rentals in Byron

Harbor Hill Inn Cottage - Piano Suite

Cozy Duplex Unit 10 minutes to Mayo Clinic

Two story apartment, spacious!

Bin There, Done That (and Pickleball too!)

INTRO RATES /Clean & Spacious /10 minutes Downtown

Cozy home, close to Mayo Clinic!

Beautifully Designed Space. 1 Mile to Mayo Clinic

The Harvest House
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