
Family-friendly holiday rentals in Cayce
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Cayce
Guests agree: These family-friendly homes are highly rated for location, cleanliness and more.

Lucy’s Place
This 950 sq ft minimalist home is the perfect place to relax with family and friends. This West Columbia home is in a convenient spot for you to spread out and make yourself at home. The home is only 2 miles off of the interstate if you are just traveling through. You’ll be about 10 minutes from the University of South Carolina, Colonial Life Arena, the Statehouse, Riverbanks Zoo, Williams Brice Stadium, the Vista, The Columbia Riverwalk and many more local attractions if you are staying a while

Heathwood 2Br/1Bath Cozy Home
Close to everything when you stay at this centrally located duplex. Close to the grocery store and restaurants. Five Points (1.5 miles), the Vista (2.5 miles), Township Auditorium (2 miles), USC (2 miles), and Ft Jackson (3 miles). This freshly renovated unit includes 2 bedrooms, 1 bath, fully equipped kitchen (including a k-cup coffee maker), washer and dryer. Both bedrooms have memory foam beds (1 King & 1 Queen). Keyless entry. Off street parking for 2 cars. COC Permit STRN-001336-10-2026

Columbia’s Best Airbnb
Take it easy at this unique and tranquil getaway. Our Airbnbs are the nicest in each town. From our known luxurious mattresses to the best kept secret… 3D luxury digital Massage chairs relax you from any stressful situation. See why we are ambassador Airbnb host. Stay at this location and you are 5 to 10 minutes to the USC baseball, basketball and Football. Campus is same. Airport is 4 miles. Great kid activity at EdAdventure kid museum. I 26, I-77 and downtown Columbia are minutes away.

Lizzi & Scott’sTiny Guest House secluded USC-Vista
Welcome to our tiny guest cottage hidden in the heart of the city. It's within blocks of restaurants, coffee shops, an art movie house, and a lovely river walk. The Lace House/Governor’s Mansion, business district, MiLB & UofSC are a short walk or bike ride away. At the rear of our home, it’s private, secure & quiet. A partition & movable screen separate the bathroom area. There’s a smart tv, small fridge, microwave, coffeemaker & work-table.24 hr self check-in. STRO-000579-03-2024

The Avenues Bungalow
This space is great for a solo traveler or a couple! Great location, quiet neighborhood, close to everything. Mile and a half from USC campus (Carolina Baseball stadium, Colonial Life Arena and State house). Five miles from airport. Three miles from Williams-Brice Stadium. Three Miles from 5 points. Music venues, restaurants and riverwalk around the corner! Please note: This is a studio apartment in the back of a single family home. Private driveway, entrance and space.

Lux Tinyhome near DT/USC/Ft. J.
Experience unique glamping in a "tiny but mighty," private 300-sq-ft one-of-a-kind retreat. Built around trees and fully fenced for seclusion, it includes washer/dryer, a kitchenette, and large windows with blackout drapes for cozy nights. Perfect for couples or small families, located beside our historic farmhouse airbnb. Prefer an ever more elevated luxury escape? Are your desired dates booked? Discover our new close by Luxury Skylight Spa Cottage (in our profile).

High-styled Historic - (UofSC)
Built in 1959, this home has been completely remodeled with modern luxuries, and original hardwood floors throughout still tell the tales of decades of love and history. The decor gives a nod to a New York City loft style space, with a blend of both clean modern lines and warm rustic finishes. 1.2 mi - Steel Hands Brewing 1.8 mi - University of South Carolina 2.2 mi - Riverbanks Zoo & Garden 3.6 mi - Williams Brice Stadium 4.9 mi - Columbia Metropolitan Airport

In Columbia Metro! Easy drive to Fort Jackson/USC
Metro Columbia. 1.5 miles to USC. 9 miles to Fort Jackson! Entire single family home. Two bedrooms. One has a KING bed and the other has a QUEEN bed. One bath. Additional rollaway bed in an enclosed sunroom. Includes linens, sofa, loveseat, refrigerator, dishwasher, garbage disposal, wash machine, dryer, outdoor covered patio with rocking chairs and dining table overlooking the huge fenced, private backyard. Bright, comfortable, quiet. Plenty of parking.

The Toad Abode Studio
Relax and unwind in this cozy, centrally located studio. Perfect for travelers, the space features a comfortable double bed, work desk, cozy reading chair, and TV for your downtime. The kitchenette area includes a microwave & mini fridge with ample coffee & tea supplies, while the bright bathroom offers plenty of natural light. All the essentials you need for a comfortable stay. **Checkout on a Monday for more options at a discounted Sunday rate.

Cozy Rosewood Bungalow
Keep it simple at this peaceful and centrally-located place. Rosewood is convenient to so much of Columbia - and our place is in a super-walkable location! Publix is about 2 blocks away, and there are quite a few restaurants (and a brewery) within walking distance. We're also quite convenient to Fort Jackson and MUSC. The street is quiet, and the entrance and parking for the bungalow are behind a 6-foot fence, so it offers great security too.

Brand New Studio Guest House with Full Kitchen.
Enjoy a stylish experience at this centrally-located house. Within a one mile radius of downtown Columbia, University of South Carolina, Benedict College stadium, Prism Health Richland Hospital, Prism Health Baptist Hospital and MUSC medical center. Fort Jackson is less than 10 minutes away! Certified service animals only are welcomed with a fee. There is also a fee for guest under the age of 25.

Las Flores guesthouse in North East Columbia
Private spacious suite. This private suite is great for remote work or sort vacation to Columbia SC. This place locate in North East Columbia, 7 minutes to Fort Jackson military base also great for military graduation [Amenities ] refrigerator, coffeemaker, Microwave, Smart tv, couch, dining table, and of course a king size bed The neighborhood is very clean, peaceful, quiet and safe
Popular amenities for Cayce family-friendly rentals
Family-friendly home rentals with a hot tub

Panoramic Lakefront with Hot Tub

Unit A: Private Jacuzzi Suite w/Laundry + Fridge

Cute & cozy cabin in Lexington, SC

Lazy Creek Cove Cottage w EV Plug!

The Farmhouse @ Goat Daddy's

Lake Retreat

The Indigo - 2BR w/Hot Tub & Outdoor Space

Lakefront w pool, dock and pool table, sleeps12
Family- and pet-friendly home rentals

Cozy 3 BR Bungalow Located in Downtown Columbia

Serenity: Ridiculously Comfy Beds/Recliners, USC

Gamecock Cottage @ Lake Murray-Waterfront w/ Dock

Downtown Blue BoHo w/ outdoor spaces, grill & FP

The Carolina Cottage: Near Ft Jackson, Zoo & 5pts!

Enchanting 3-Bedroom home with nightly light shows

Freshly New House

Elmwood’s Modern Blue Bungalow
Family-friendly home rentals with a pool

A Charming Bungalow Quite Convenient

Luxury Cozy Retreat with Private Pool

Private Apartment in the woods

Lavish Home 4BR/3BA, King, Games, Grill, Pool!

Saluda Retreat

Peaceful Retreat Two

Modern condo, closest to the University of SC

Crepe Myrtle Cottage in Lake Carolina/Columbia,SC
Quick stats about holiday rentals that are family-friendly in Cayce

Total holiday rentals
Explore 260 holiday rentals in Cayce

Nightly prices starting at
Cayce holiday rentals start at $70 NZD per night before taxes and fees

Verified guest reviews
Over 15,280 verified reviews to help you choose

Pet-friendly accommodation
Find 110 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
160 properties have a dedicated workspace

Wi-Fi availability
260 of Cayce holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Cayce rentals

4.8 Average rating
Cayce stays are highly rated by guests—averaging 4.8 out of 5!
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- Riverbanks Zoo and Garden
- South Carolina State House
- Congaree National Park
- Frankie's Fun Park
- Columbia Museum of Art
- South Carolina State Museum
- University of South Carolina
- Colonial Life Arena
- Williams Brice Stadium
- Columbia Metropolitan Convention Center
- West Columbia Riverwalk Park and Amphitheater
- Dreher Island State Park
- Soda City Market
- Riverfront Park
- Edventure
- Saluda Shoals Park




