Holiday houses in East Cleveland

Home in University Circle

A modern kitchen area features gray cabinetry and a stainless steel sink, complemented by a sleek, dark countertop. A black stove and microwave are seen, alongside a refrigerator with a textured finish. White tiles line the backsplash, reflecting light from the overhead fixture.

4.93 out of 5 average rating, 377 reviews

Historic Little Italy Garden Apartment

Stylish garden apartment. This retreat blends modern comfort with the vibrant cultural charm of Historic Little Italy. Steps away from shops, restaurants, and lively bars. Wade Oval Park is a nearby cultual hub, home to The Art & Natural History Museums and Botanical Gardens. Easy access to Case Western Reserve, Cleveland Clinic and University Hospital. Walk to the beautiful Lakeview Cemetary or take transit downtown to 4th street. Perfect for short or long stays. Book for a memorable time.

ValueLocationDecor

4.95 out of 5 average rating, 21 reviews

Blue Historic House by Cle Clinic, CWRU, Museums

Entire private house near Cleveland Clinic, ideal for families, travel nurses, and business travelers. 10-min walk to Cleveland Clinic with quick access to University Hospitals, Case Western, Little Italy, museums, and downtown Cleveland. 3BR house + sofa bed in living room, dedicated workspace, full kitchen, washer/dryer, free parking, fast Wi-Fi, private backyard, and self check-in. Quiet, clean space for short or extended stays, including monthly stays. Green house next door also available.

LocationFamilyAccuracy

4.98 out of 5 average rating, 48 reviews

Relax at New Home & Walk to Cle Clinic

Come join us at Home Sweet CLE! * A 2023 🆕 construction, luxury single family home 🏡 * 3 bedrooms 😴: 1 king bed 🛏️, and 2 queen beds 🛏️ 🛏️ * 2.5 bathrooms 🫧: half bath downstairs, 2 full baths upstairs 🛁 ↗️ * 2 car 🚙 🚙 detached garage + plenty of driveway parking *.3 miles to Fairfax Market a 🆕 grocery store 🛒 * .5 miles to Cle Clinic Heart Center 🫀🏥 * Within 10 min drive to Uni Hospital 🏥, 🌈Rainbow Babies Hospital, the 🇺🇸 VA hospital , CWRU🎓, & University Circle ⭕️.

FamilyValueIndoor spaces

A shared spa area features a hot tub beside a stone-paved space with a large table and six chairs, partially shaded by a green umbrella. The area is enclosed by greenery and a rustic brick wall, providing a cozy and private setting.

4.98 out of 5 average rating, 419 reviews

Rare Cleveland Apt: Little Italy! W/Sauna&Hot tub!

Fall in love with this charming, newly updated 1-bedroom, 1-bath lower unit triplex apartment situated in the heart of Little Italy, walking distance from University Circle, UH Hospital, Cleveland Museum of Art, Botanical Garden, Public Transportation and much more. Apartment is complete with a well-equipped kitchen, Smart TV, laptop workspace, and modern furnishings, this vacation/business rental delivers all the essentials so you can spend more time relaxing and exploring.

ValueFamilyQuiet

4.81 out of 5 average rating, 31 reviews

Stylish 1BD Condo I Minutes From Little Italy

Our apartment is ideally located near Cleveland Clinic, making it perfect for medical professionals, patients, and families. You’ll also be minutes from the Health Education Campus, Case Western Reserve University, University Hospitals, and the museums of University Circle. Enjoy a short drive to the charming Little Italy neighborhood, filled with authentic Italian restaurants, cafés, and bakeries, while downtown Cleveland is just 5 miles away for dining and entertainment.

ValueLocationCheck-in

Guesthouse in Cleveland Heights

The exterior of a charming brick carriage house is showcased, featuring a steeply pitched roof and large, shuttered windows. Lush greenery surrounds the entrance, with flowering plants visible near the driveway, providing a welcoming ambiance on the sunlit day.

4.98 out of 5 average rating, 547 reviews

Clean and Cozy Carriage House Getaway

Sunny and cozy carriage house in safe, historic neighborhood - perfectly appointed for overnight guests or extended stay visitors. Close proximity to Cleveland Clinic, Case Western, John Carroll University, Shaker Lakes & University Circle. Enjoy the charm of staying in this premier neighborhood with the comforts of home including updated kitchen, furnishings, bed/bedding and spa shower. Beautiful, safe, tree-lined street with private entrance and parking spot.

ValueLocationCleanliness

4.91 out of 5 average rating, 23 reviews

Downtown CLEV 2BR | Free Garage + Pets, W/D

Live in the heart of Little Italy, steps from University Circle, UH, and CWRU, with Cleveland Clinic just minutes away. This professionally designed 2BR 1BA suite has: ✓ Sleeps up to 6 ✓ Includes secure gated parking ✓ A gym ✓ An in-unit washer/dryer, ✓ and resort-style community amenities Whether you’re visiting for work, medical travel, or a city getaway, this centrally located space offers comfort, convenience, and a refined place to recharge.

LocationFamilyWalkability

4.79 out of 5 average rating, 24 reviews

Purple Haus - Game room w/ pool table, poker table

Welcome to the Purple Haus, the "pur"fect short-term rental for your vacation, staycation, or baecation. Enjoy staying in a creative, comfy, modern, yet fun, and playful space. The Purple haus is a "purple" (colored) themed Air bnb filled with multiple photo ops throughout the home. Located on the eastside of Cleveland Ohio, 10 minutes from Downtown CLE. Minutes away from I 90 and on the RTA bus line. The Purple Haus is what you have been looking for!

FamilyLocationCheckout

A modern kitchen features sleek stainless steel appliances and a large sink integrated into a spacious countertop. An open living area is visible in the background, showcasing a comfortable sofa and large windows that allow natural light to illuminate the space.

4.92 out of 5 average rating, 120 reviews

Elegant 1 BDR | Cleveland Clinic | Free Garage

* Parking garage fully open as of May 2024 * HIGHLIGHTS: One complimentary garage parking, brand-new building that is across from the Cleveland Clinic, Meijer Fairfax Market located downstairs (a full-sized grocery store with a coffee shop and a gift shop), Cleveland Clinic shuttle stop in front of the building, in-unit washer and dryer, private fitness center, night time security staff, and included WiFi. Read more below!

FamilyLocationKitchen

Apartment in Cleveland Heights

A bright dining area is showcased with a wooden table and built-in cushioned seating. A large window allows natural light to illuminate the space. A world map hangs on the wall, adding an element of global inspiration to the modern decor.

4.86 out of 5 average rating, 285 reviews

The Maproom Room | 10 Mins to Cleveland Clinic, UH

🗺️ Map-themed studio • Sleeps 2 ✨ Fully renovated • Clean + modern ☕ Kitchenette • Coffee maker • Microwave & Instapot 📺 Smart Roku TV + streaming apps 🚗 Off-street parking for midsize cars (1 spot) 📍 10 min to Cleveland Clinic + University Circle Modern comfort meets world travel charm in this map-inspired studio apartment — thoughtfully designed and ideally located near Cleveland’s best cultural attractions.

LocationFamilyKitchen

Shipping container in Cleveland

A shipping container, marked with 'COSCO,' is being lifted by a machinery in an outdoor area. The background features other containers and a partially visible structure, with a clear sky above.

4.92 out of 5 average rating, 156 reviews

Planes, Trains and Automobiles

Have you ever imagined staying in a shipping container? Neither did we — until we created this one-of-a-kind mini home in Cleveland! Built from two repurpose shipping containers, this space blends industrial vibes with surprising, comfort and style. When the Amtrak comes by at 6 AM you will feel alive and part of the action! We even have an incinerating toilet!!That yes does burn your poop!💩

ValueLocationView

4.62 out of 5 average rating, 34 reviews

Home in South Euclid

South Euclid Home 10 Minutes to Cleveland Clinic

Located just a 5-minute drive from The Beachwood Mall and a 2-minute walk to the vibrant Cedar-Warrensville shops, bars, and restaurants, this home offers convenience at its best. CVS, Whole Foods, and the local library are all within walking distance. Plus, you're only 10 minutes away from the Cleveland Clinic, University Hospitals, the Cleveland Orchestra, and The Cleveland Museum of Art.

ValueLocationComfort

Popular amenities for East Cleveland holiday rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Other great holiday rentals in East Cleveland

4.9 out of 5 average rating, 311 reviews

A cozy dining area is highlighted by a large claw-foot antique dining table, surrounded by contemporary seating. A prominent stone fireplace, framed by wooden paneling, adds character to the space. Bookshelves can be seen in the background, contributing to the rustic charm.

Cabin in Euclid

Century-plus Summer Cabin - The Perfect Getaway!

LocationFamilyLaundry

4.87 out of 5 average rating, 97 reviews

New Luxury Studios | Walk to Cleveland Clinic

ValueLocationIndoor spaces

4.75 out of 5 average rating, 87 reviews

Apartment in Cleveland

First Floor Apt Near Arts District and Beach

FamilyValueKitchen

A cozy living area is presented with two dark armchairs facing a modern television mounted above a decorative white mantel. Natural light filters through large windows, illuminating the gray walls and stylish area rug. An open view leads to the dining area and kitchen beyond.

4.61 out of 5 average rating, 108 reviews

*CONVENIENT!>next to CWRU, UH, CC!

LocationValueCheckout

The image shows a well-kept front yard with neatly mowed grass, featuring a concrete pathway leading to the entrance of a two-story home. A sign is positioned on the lawn, and a neighboring house is visible to the left.

Apartment in Cleveland

4.69 out of 5 average rating, 348 reviews

Winfield's Off Waterloo

LocationValueHospitality

5.0 out of 5 average rating, 8 reviews

Modern and cozy home w/ fireplace

LocationLong stayCleanliness

A bright living area features a teal sofa adorned with patterned pillows, set against a backdrop of exposed brick walls. A glass coffee table sits atop a striped rug, accompanied by two white stools. Warm wooden flooring complements the overall design.

Apartment in Cleveland

4.79 out of 5 average rating, 90 reviews

Chic Coventry: Save 10% on 2+ Nights+Late Checkout

FamilyLocationWalkability