Holiday rentals with a patio in Florence County

Peaceful cabin retreat! Collins Quarters

In the middle of town, this unique place has a style all on its own. Inspired by Mountain Bungalows and Spanish accents, this one of a kind home sits directly beside MUSC in Florence SC. Close to everything you can possibly need, amenities include: 1 King bed, 1 Queen bed, 1 twin bed, 1 Full Size sofa bed, a full kitchen with living room and dining area, outdoor shower, and a nice sizable front porch to sit and sip your morning coffee looking over a beautiful landscaped front yard. Dog friendly!

The Hideaway at Fox Fields

The Hideaway at Fox Fields tiny home sleeps up to 4 with one bedroom and a sleeper sofa (both queen size beds). The bathroom has a walk-in shower. There's full kitchen with dishwasher, oven, microwave, and dishes, plus a washer/dryer combo. There's TV (guests use their own streaming accounts), game cabinet, and two mini-split AC units. The front porch overlooks a pond; cows are in the pasture at times. Located 10 minutes from I-20 Exit 137 and 5 minutes from The Cabin at Old Spur wedding venue.

Comfortable 3BR Home Near McLeod & MUSC

This cozy three-bed, one-bath bungalow is minutes from downtown Florence and local medical facilities. Set in a small neighborhood, this cozy retreat is designed with extended-stay guests in mind. You’ll enjoy reliable WiFi, a smart TV, a fully equipped kitchen, the convenience of an in-unit washer and dryer, free onsite parking, a large front porch and a fenced in backyard. Whether you’re here for a few days or months, this house is a perfect space to call home. Please inquire about pet fees.

The Equestrian Retreat I95/I20

Enjoy the perfect blend of comfort, convenience, and country charm at our newly 2026 built home just outside Florence, SC. Located on a peaceful 1/2 acre lot with beautiful countryside views, this spacious 1300 sq ft 3-bedroom, 2-bath home is ideal for overnight travelers, family vacations, work trips, or extended stays. 1.5 hour to Myrtle & just 5 minutes from Interstate 95 and Interstate 20, you'll enjoy quick and easy highway access while still experiencing the tranquility of rural living.

Vintage Cottage @ I-20/I-95

Welcome to our new vintage cottage. Enjoy the old (‘30’s farm sink, ‘50’s refrigerator, etc.) along with modern amenities (microwave, wi-fi, etc.). Bottled water, coffee, and snacks are provided upon arrival. It’s equipped with a queen bed, a full bathroom, small kitchen and living room. Darlington Raceway is just 15 minutes away and Highway 76 is two miles away to take you directly to Myrtle Beach. Only 5 minutes to I-20/I-95, restaurants, malls, parks, golfing, tennis, soccer and more.

Cozy Florence Retreat Near Civic Center & I-95

Welcome to your Florence getaway! This bright, modern, and cozy Welcome to your Florence getaway! This bright, modern, and cozy home is perfectly located near I-95, Downtown Florence, the Florence Civic Center, and Darlington Raceway. Enjoy shopping and dining at nearby Buc-ee's, or take a short 1.5-hour drive to Myrtle Beach. The home features a fully equipped kitchen, comfortable bedrooms, and convenient parking—ideal for road trips, events, family stays, or a relaxing Southern escape.

Governor's Square at Coventry @ I-20/I-95

This private, cozy two bedroom 1 1⁄2 bath condo has recently been renovated and is discounted for longer stays. The condo includes 2 bedrooms. It's located among quiet neighborhoods for peaceful walks or for sitting outside on the private patio. Within five minutes you’ll find access to I-20 & I-95, restaurants, malls, civic center, movie theater, Florence rail trail and parks, golfing, tennis, soccer and more. Highway 76 is two miles away and takes you directly to Myrtle Beach.

Pickle in the park - 1 bedroom studio apartment.

Come stay and play pickle ball at the courts in beautiful Timrod Park located in the heart of Florence or just keep it simple at this peaceful and centrally-located private 1 bedroom studio apartment. You’ll have plenty of parking with a spacious outdoor area. Everything you need is conveniently located within walking distance to the local Piggly Wiggly grocery store, library and award winning Historic Downtown. We look forward to welcoming you.

Renovated 2 BR/2 B Townhouse Cozy & Clean

Keep it simple at this peaceful, centrally-located, and renovated townhouse close by I-95 and I-20 and within 15 mins. to the Florence Center, downtown Florence, many restaurants, and McLeod and MUSC Florence. House is located in a safe neighborhood. Enjoy being outdoors? Relax outdoors on your own private patio, go on a walk around the neighborhood, or go on an adventure. The Rail Trail & Ebenezer Park are minutes away. Utilities included.

Enchanting Treehouse with Modern Amenities

Perched on 20 acres along Catfish Creek, this enchanting tree house allows you to appreciate nature from a birds eye view. Whether it’s kayaking, canoeing, or exploring along the creek; relaxing in the hammocks and swings; engaging in a board game; or roasting marshmallows at the fire pit, Amenities include a full kitchen with full bath, outdoor shower, booth seating in dining table for up to 8, 2 bunk beds and loft style sleeping.

Modern 3BR/2BA Home in Lake City – Quiet & Central

Modern, clean 3BR/2BA home in quiet Lake City neighborhood—just minutes from shops, dining, and downtown. Each bedroom has a comfy bed, fresh linens, and a flat-screen TV. Kitchen includes basic cookware, utensils, and a Keurig with coffee pods. Enjoy free Wi-Fi, washer/dryer, and ample parking. Perfect for business, family, or a relaxing getaway. Centrally located and fully equipped for a comfortable stay!

Creekside Cottage - 4 Bedrooms

Enjoy your staying on this newly renovated Pet friendly house. Treat yourself with a cup of coffee at the deck while you watch your furry baby play in the big fenced backyard. This house is centrally located in Florence. Only minutes from downtown Florence, Grocery stores, Pharmacies, Restaurants, MUSC Hospital, McLeod Hospital. This house has two king bed bedrooms and two Queen bed bedrooms.