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House holiday rentals in Isla Grande

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Top-rated house rentals in Isla Grande

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Guest favourite
Two rustic-style cabins are set along the shoreline, surrounded by lush tropical trees. A wide patio is furnished with colorful chairs, offering views of the water. The natural beauty of the landscape is complemented by the tranquil waves gently lapping at the shore.
Home in La Guaira
4.97 out of 5 average rating, 110 reviews

Puntita Manzanillo, fantastic sea and jungle

Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Guest favourite
An open-concept loft is showcased with a high, sloped ceiling and large windows that invite natural light. Comfortable seating is arranged around a glass table, while a dining area and a cozy sleeping space can be seen in the background. Nature views are visible through the windows.
Home in Santa Rita Arriba
5 out of 5 average rating, 9 reviews

The Bird's Nest in the Clouds

Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Superhost
Home in Isla Grande
4.63 out of 5 average rating, 8 reviews

Beachfront House in Isla Grande Province of Colon

Ven a relajarte en esta hermosa y acogedora casa frente al mar, situada en una isla mágica donde la gastronomía es exquisita con una gran variedad de mariscos y de sus playas encantadoras de aguas cristalinas y arena blanca. Hay una gran variedad de actividades por hacer y toda una cultura costera por conocer: Desde los bailes folclóricos (congo) hasta su hermoso pueblo de tez morena. No olvides preguntarnos de los toures turísticos disponibles a las islas cercanas, ¡No te arrepentirás!

Top Guest favourite
An outdoor terrace features a table with seating for four, framed by colorful chairs in red and blue. A hammock is suspended nearby, with the serene view of the water and distant hills providing a tranquil backdrop. Natural light illuminates the space, highlighting the coastal setting.
Home in Juan Gallego
4.94 out of 5 average rating, 65 reviews

Beachfront · Large Sea View · Family Friendly

Welcome to Kasa Leilani, a charming beach house nestled between the jungle and the reef in the heart of a natural park. With stunning views of the nearby Caribbean islands, this peaceful retreat offers the perfect blend of nature and comfort. Surrounded by abundant wildlife, you can relax, explore the reef, or discover the island and crystal-clear waters. Kasa Leilani provides a serene escape for nature lovers and beach enthusiasts alike, offering an unforgettable tropical getaway.

Guest favourite
A modern living area features a dark sectional sofa with a decorative pillow. Natural light filters through stylish striped blinds, highlighting the sleek marble flooring. A wooden cabinet and coffee station are positioned in the background, creating a functional and inviting space.
Home in Colón
4.88 out of 5 average rating, 32 reviews

Family Style Living, in Colon #3

Relax with the whole family at this peaceful place. This house is located on reverted Areas transferred back to Panamá, called Arco Iris, there’s plenty of space outside, the inside consist of a modern combination living room+kitchen, bathroom and a large bedroom with acomodación for 4 guest, the place is Airconditioned with Celling fans in the living room and bedroom. This is a third house constructed next to our first rental called, Family Style Living and close to the Panamá Canal

Guest favourite
Home in La Guaira
4.82 out of 5 average rating, 34 reviews

Bella Casa, Caribbean Sea, Juan Gallego (waterfront)

Hermosa Casa de Playa, frente al mar caribe, para descansar y relajarse al 100%. La Casa cuenta con una ubicación privilegiada, mantiene 4 habitaciones (una de ellas cuenta con una mampara para dividir de la sala y ampliar esa área en caso que se desee), sala, comedor, terraza privada, frente a Isla Grande. 4 habitaciones. 3 tienen TV con cable y una TV extra en la sala. Todas con con Aire Acondicionado. Cuenta con 2 baños completos. Cocina equipada y lista para disfrutar y Wifi

Superhost
The image captures a spacious loft featuring large triangular windows, allowing natural light to flood the interior. A view of the surrounding landscape, including mountains and water, can be seen through the windows. The outdoor area includes wooden seating on a terrace.
Home in Portobelo
4.78 out of 5 average rating, 63 reviews

CASA DINIS - LOFT - WITH VIEW BAHIA DE PORTOBELO

Relax these in the Caribbean! Welcome to Portobelo! In this historic World Heritage village you have the opportunity to live a real experience and share with a people full of history, identity and beautiful people! I am happy to share the Loft for your visit to Portobelo. It is a house with local identity and European style, this lovingly done project is in front of the beautiful Bay of Portobelo and in the heart of the village... Welcome to the Loft of Casa Dinis!

Guest favourite
Home in Maria Chiquita
4.89 out of 5 average rating, 18 reviews

Villa with Private Terrace in Playa Escondida

**El apartamento** Planta Baja con terraza privada y la playa está a solo unos pasos ! Nuestra villa es una de las opciones más accesibles para familias con niños y adultos mayores !! >>>>podras llegar a la playa y a las piscinas sin preocuparte por subir escaleras ni usar elevadores <<<< *Amenidades del Resort* -Gimnasio -Kayak, botes de remo, Bohío con BBQ (reserva previa) -Restaurantes -Cancha de fútbol, pádel y volleyball -Parque acuático -Tiendita

Superhost
A charming house is set amidst lush greenery, featuring a sloped tiled roof and wooden pillars. Tropical plants and vibrant flowers surround the exterior, creating a serene atmosphere that integrates with the natural landscape.
Home in Cacique
5 out of 5 average rating, 4 reviews

House in Cacique- Jungle and Sea

Finca Cacique offers a peaceful jungle escape just 5 minutes by foot from Cacique beach. This 4-bedroom house (3 with A/C, 1 with fan) is surrounded by nature and visited by monkeys, sloths, and birds. We have 2 kayaks for rent to explore nearby islands such as Isla Mamey and the Tunnel of Love. Enjoy the jungle’s beauty with the sea nearby. (Note: not beachfront property.) Perfect for nature lovers seeking tranquility and adventure.

Superhost
A spacious dining area features a long wooden table surrounded by multiple chairs, all under a high wooden ceiling with a ceiling fan. Natural light enters through a nearby door, leading to an outdoor space filled with greenery.
Home in La Guaira
4.56 out of 5 average rating, 16 reviews

Beach house, facing the sea!

Experience total calm in our Oceanfront House, an ideal family retreat, where you will feel relaxed and experience the tranquility you dream of. You will have the sea 24 hours a day, you can hear the waves and the sea breeze everywhere. Whether you're relaxing on the terrace, reading a good book, or watching the beautiful sunsets of La Guaira in Colón, this space reconnects you with yourself and nature. Ideal for families

Guest favourite
A spacious wooden chalet is positioned on a lush green slope, surrounded by tropical vegetation. The structure features an open terrace with railings, allowing for expansive views of the sky. A few palm trees and various plants complement the natural landscape.
Home in Cacique
4.96 out of 5 average rating, 27 reviews

El Paraiso

We are pleased to present a large beautiful house for rent between the village of Cacique and the village of José Pobre in Portobelo National Park. Overlooking the Caribbean Sea, nestled in the jungle, this house has a unique character in the area. Its direct access to a small wild beach, with an exciting reef for snorkeling fans, makes it a privileged place. Ideal for groups and families wishing to reconnect with nature.

Superhost
A view of the house, set against a backdrop of palm trees, showcases its two-story structure with large windows and a red-tiled roof. The property overlooks a calm lagoon, with a stone pathway leading down to the water's edge.
Home in Palenque
5 out of 5 average rating, 9 reviews

Beach Front Caribbean Paradise at Palenque

Amazing beach front view will make you feel in touch with the ocean and its creation. A perfect place to relax and meditate . Located 2 hours and a half from Panama City is a place to enjoy the beach while listening to the sound of the waves and swim in shallow waters with sand button. You wilo feel the beauty and power of its creator!

Popular amenities for house rentals in Isla Grande

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  2. Panama
  3. Colón Province
  4. Isla Grande
  5. House rentals