Some info has been automatically translated. Show original language

Holiday houses in Isthmus of Panama

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Isthmus of Panama

Guests agree: these stays are highly rated for location, cleanliness and more.

1 of 1 pages1 / 1
Guest favourite
Two rustic-style cabins are set along the shoreline, surrounded by lush tropical trees. A wide patio is furnished with colorful chairs, offering views of the water. The natural beauty of the landscape is complemented by the tranquil waves gently lapping at the shore.
Home in La Guaira
4.97 out of 5 average rating, 113 reviews

Puntita Manzanillo, fantastic sea and jungle

Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.

Guest favourite
A beachfront house features a thatched roof and is elevated on stilts, surrounded by lush greenery and palm trees. The structure showcases a spacious porch with wooden railings, offering a shaded area for relaxation and enjoying the natural landscape.
Home in Cambutal
5 out of 5 average rating, 33 reviews

Beachfront Gem w/ Ocean Views & Prime Surf Access

Welcome to your slice of beachfront paradise! Our home sits right on Cambutal's beautiful shoreline. Gorgeous ocean views greet you from every window, while the gentle rhythm of waves creates the perfect soundtrack for your stay. We've equipped the house with Starlink WiFi and a large dining table that doubles as an ideal workspace, making this a perfect retreat for both vacationers and remote workers. The house feels like a real home – comfortable, clean, and ready for your beach memories.

Top Guest favourite
An open living space features a wooden dining table surrounded by six wicker chairs. Two hanging hammocks are displayed on the covered terrace, offering views of the lush hills. Large glass doors reflect the greenery, blending indoor and outdoor spaces harmoniously.
Cabin in Torio
4.97 out of 5 average rating, 187 reviews

Cozy open space, unique jungle views, river access

An open-style jungle home with mesmerizing treetop and mountain views. Located 10 minute walk to the beach, with a trail that leads to the River. The house is not childproof! It has three individual bedrooms, each with its own key. The price is based on the number of guests. The entire house is always yours. The house offers fiber optic WiFi and two dedicated workspaces. The property is surrounded by large trees, naturally keep the house cool and provide shelter for birds and wildlife.

Guest favourite
Cabin in Altos del Maria
4.96 out of 5 average rating, 25 reviews

Fobos – Luxury 1-Bed Cabin with Heated Pool

Relax and enjoy Altos del María and its amenities in our brand-new tiny house. With beautiful views, a private jacuzzi, and a modern design, it truly ticks all the boxes. The house is ideal for couples (2 guests) but children are welcome (maximum 2). The kitchen is fully equipped, the bathroom features a modern design, and the bedroom is cozy and comfortable. Located on a shared lot with two others houses, this tiny house is perfect for enjoying a weekend getaway or a longer stay.

Top Guest favourite
The exterior of the cabin is showcased amidst lush greenery, featuring a sloped roof and large glass windows. A wooden staircase leads up to the entrance, while a stone pathway meanders through the garden, enhancing the natural surroundings.
Cabin in Penonome
4.98 out of 5 average rating, 135 reviews

Aqeel cabin in the nature

Relax at this unique and tranquil getaway surrounded by nature. If you're lucky, you may wake up to see white-faced capuchins from your bedroom window and spot an abundance of birds, such as the crested oropendola or a toucan. The property offers river access with a sandy, beach-like area, and there is a 1 km walking trail alongside the river. With satellite high-speed internet access, you'll stay connected, though the river and sandy area may not be accessible during rainy days.

Guest favourite
The modern house is set amidst lush greenery, featuring a sleek design with large glass windows. An infinity pool is positioned on a spacious patio that offers unobstructed views of the surrounding hills, creating an inviting outdoor space for relaxation.
Home in Altos del Maria
4.82 out of 5 average rating, 323 reviews

Modern House with Great Views and Heated Pool

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.

Superhost
Home in San Carlos
4.89 out of 5 average rating, 166 reviews

El Palmar, beach 50 meters away

Listen to the waves from the privacy of our terrace and create unforgettable memories in this unique and family-friendly accommodation just steps from the beach with a private pool. El Palmar is a quiet community with several restaurants available a few steps from the house. The property is fully fenced for the tranquility and safety of children and their pets. In addition, you have wifi, cable TV in both rooms and air conditioning in the dining room and in all the bedrooms

Superhost
A tranquil dipping pool is framed by lush greenery, featuring white loungers and a large umbrella for shade. The pool area exudes a serene vibe with vibrant bougainvillea in the background, enhancing the inviting outdoor space.
Home in Taboga Island
4.94 out of 5 average rating, 219 reviews

Casa Rosie - Dream Home on Tabogá Island

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Top Guest favourite
A spacious outdoor deck features modern furniture arranged for relaxation, overlooking a lush mountainous landscape. Verdant hills and a colorful sky at dawn create a tranquil environment, inviting guests to enjoy the natural beauty and serenity of the surroundings.
Villa in El Copé
4.92 out of 5 average rating, 192 reviews

Mountain retreat

Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Top Guest favourite
Apartment in Panamá
5 out of 5 average rating, 34 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Guest favourite
A private deck features two modern chairs with a small table between them, positioned on a textured area rug. A custom-built jacuzzi is visible in the background, surrounded by a wooden railing. Natural light floods the indoor living area through expansive glass doors.
Cabin in Boquete
5 out of 5 average rating, 8 reviews

New World Casita @ Finca Panda

Mundo Novo is one of our new, one-room casitas and has one of the most incredible views on the property. Perfect for couples, singles or family with a small child, Geisha sleeps 2 people comfortably in one king bed (maximum 3 guests when using sofa). Geisha was designed with every amenity needed to have a perfect and relaxing stay. Custom-built jacuzzi, fire-pit, kitchen, incredible shower, high-speed WiFi and more

Top Guest favourite
Cabin in Jaramillo
5 out of 5 average rating, 39 reviews

Coffee Cabins - Cabin 2

Welcome to the Coffee Cabins. This is one of four stunning A-frame cabins perched on the side of a mountain in the middle of a coffee field. You’re literally surrounded by coffee, both on the trees and in your kitchen with the complimentary coffee grown right here on the farm. Enjoy larger than life views to both the north towards the continental divide and to the west framing Volcan Baru, Panama’s highest peak.

Popular amenities for Isthmus of Panama holiday rentals