Guesthouse holiday rentals in Lee County

An outdoor area features a well-maintained gravel landscape, framed by lush greenery and palm trees. A round table with four vibrant red chairs offers a place for gathering, set against a backdrop of a pastel-colored guest house with a distinctive turquoise door and awning.

4.99 out of 5 average rating, 113 reviews

Private guest house—minutes to the best beaches!

Experience the charm of Fort Myers in this quaint, private guest house located in the historic district. Perfectly situated near Fort Myers Beach (12 miles), Sanibel Island (16 miles), downtown (4 miles), some of the areas best restaurants (some even walking distance), grocery stores, & convenience stores. Easy access to Southwest Florida International Airport & FGCU. Uber and Lyft are easy access. The neighborhood is peaceful, safe, & walk friendly. Book now for a convenient and memorable stay.

4.96 out of 5 average rating, 141 reviews

The kitchenette is equipped with white cabinetry, a microwave, and a sink. A small table with two chairs is positioned near the door, providing a space for meals. The light-colored tile flooring and bright lighting create an airy atmosphere.

Guesthouse in Cape Coral

Cozy Studio with sunny outdoor patio

Peaceful & centrally located studio with private patio. 15-20 minutes from downtown Cape Coral & downtown Fort Myers. Driving distance to several beaches. There’s a kitchenette for basic cooking. oKing size bed! The studio is attached to the main house but is a completely separate & private space with a private entrance. Private patio with table. Beach essentials included. Cape Coral Yacht Club beach 15 min away Ft. Myers Beach 35 min away Sanibel Beach 40 min away Naples Beaches 60 min away

The modern kitchen is equipped with white cabinetry and stainless-steel appliances. A circular table with seating for four is positioned near a large glass sliding door that allows natural light and offers views of the outdoor space. A ceiling fan adds comfort to the room.

4.98 out of 5 average rating, 190 reviews

Waterfront Hideaway

This picturesque Airbnb is a hidden gem nestled along a canal, one minute boat ride to the Caloosahatchee River. The living room, bathed in natural light is perfect for taking in the scenic views. The spacious bedroom has a king-size bed, ensuring a night of blissful rest. The full kitchen is equipped with all modern appliances. Close to Sanibel & Fort Myers Beach. Bring your boat & dock it on the seawall, ready to set sail whenever your heart desires. Book now - your coastal paradise awaits!

Superhost

A compact kitchen is equipped with modern appliances, including a coffee maker, microwave, and refrigerator. A granite countertop offers ample workspace, while cabinets provide storage. Soft blue lighting from a sign enhances the atmosphere, and a small dining table is positioned nearby.

Guesthouse in Cape Coral

4.8 out of 5 average rating, 111 reviews

Perfect Place for your Vacations

This Guesthouse has everything you need for your vacation, it is central located, in a peaceful and safe neighborhood and have a very well distributed space. Its located few minutes from the Caloosahatche River and the beautiful beaches of the Gulf of Mexico, it includes bicycles, kayaks, umbrella, beach chairs, fishing rods and other items that will enhance your vacation. It is also very close to highly recommended restaurants, famous shops (walmart,Publix, McDonald) and other essential places.

A refreshing saltwater pool is surrounded by a patio featuring colorful pavers. Palm trees provide shade, and lounge chairs are positioned nearby, creating a serene space. A gazebo is seen in the background, along with tropical landscaping and a white fence enclosing the area.

4.96 out of 5 average rating, 24 reviews

Kayaking Paradise • Pool . Canal front

$million home located in the heart of S Fort Myers close to EVERYTHING. Kayak out of the pet friendly fenced backyard through miles of pristine mangroves, gorgeous saltwater pool; 13 miles to Sanibel Island, 6 miles to Fort Myers Beach. Walk to Lakes Park and visit the farmers market/Wednesday mornings or walk to Castle Golf (award winning mini golf). Biking trails everywhere. Near: Walmart, restaurants; Publix and Aldi's. 1 Bed/1 bath/kitchen 1st floor unit with own entry. en la planta baja

A modern kitchen area includes white cabinetry, a full-sized refrigerator, and an oven. A round dining table surrounded by four black chairs is positioned near a window. A washer and dryer are tucked into the corner, offering convenient amenities.

4.85 out of 5 average rating, 26 reviews

Downtown Fort Myers Florida - Home Away From Home

Welcome to a peaceful studio apartment nestled in Fort Myers historical district of Edison Park just 500’ from the Edison & Ford Winter Estates just a short walk to downtown Fort Myers along Royal Palm tree lined McGregor Blvd. Visit the Downtown River District’s restaurants, bars, shops, Caloosa Sound Convention Center, theaters and minutes away from Sanibel, Captiva, Fort Myers Beach, golfing, multiple baseball parks (Twins & Red Sox), Southwest Florida International and Punta Gorda airports.

The guesthouse exterior features a modern design with a metal roof and a two-car garage. Landscaped front yard with green grass and decorative plants is visible, creating a welcoming entrance. A secluded porch area with seating is present, surrounded by trees and shrubs.

4.91 out of 5 average rating, 107 reviews

Hezekiah's 2 Story Guesthouse with Pool

Hezekiahs Guesthouse a perfect getaway in sunny SWFL! You will be staying in the guest house with a private entrance. This property has a living room and kitchenette downstairs and a spacious bedroom with master bathroom upstairs. This Airbnb is attached to our home. You will have access to the pool and our outside grill area. Complimentary coffee, water, soda and more.. Lots of nearby restaurants and shopping. Minutes away to Fort myers or Bonita beach, FGCU and RSW Airport and Hertz Arena.

The entrance of the suite features a modern front door with horizontal panels. A paved pathway leads to the door, surrounded by well-maintained landscaping with colorful plants and shrubs. A clear blue sky and scattered clouds provide a bright backdrop.

4.86 out of 5 average rating, 21 reviews

Guest Suite Retreat

Enjoy a suite retreat at this centrally located lodging. Stay for business or pleasure just a short walk from beautiful, Royal Palm lined McGregor Blvd. Also, nearby are the tasty Mcgregor Cafe and Mcgregor Pizza. A 10 min drive will take you to historic downtown Ft. Myers with views of the Caloosahatchee River and lots of great restaurants and shopping. A 25 min drive in the other direction and you will be on lovely Ft. Myers Beach, experiencing all the fun and sun it has to offer. ***No Oven

A bright and airy room features a king-sized bed with plush linens, framed by soothing blue walls. A flat-screen TV is mounted on the wall, and two patterned chairs are positioned to enjoy the view. Large glass doors open to a private patio overlooking the water.

4.93 out of 5 average rating, 131 reviews

Get Away to the Mango Cottage

Nestled on the outskirts of Historic downtown Fort Myers abides the Mango Cottage overlooking the Caloosahatchee River. The sunsets are amazing. You will enjoy the luxurious linens on the King sized bed to the relaxing patio it will delight the senses. You will be able to enjoy the 60" flat screen Smart TV! . The cottage is complete with Keurig coffee maker, toaster, microwave/convection oven and grill outside. We are minutes from restaurants and night life. This is a NON-SMOKING property.

A spacious sleeping area is highlighted by a large bed adorned with a colorful floral duvet cover. Natural light filters through the window treatments, illuminating the room. A decorative mirror and a functional air conditioning unit complement the minimalist design.

4.92 out of 5 average rating, 51 reviews

Amazing & private Studio in Midtown!

Enjoy comfort, convenience and unbeatable location at this updated Studio in the very safe Midtown Fort Myers. 2 TV's Private entrance and parking for 2 vehicles. Walk to FSW College, FGC University, Barbara B Mann Theater and Suncoast Arena 4 supermarkets, 17 Restaurants/Caffes within 1 mile. 2.6 miles to Gulf Coast Medical Center 9 miles to Fort Myers Beach 8 miles to Downtown Fort Myers 11 miles to (RSW) Airport 17 miles to Sanibel Island 50-amp outlet and Level 2 EV charger for EV.

Superhost

A thatched-roof gazebo is surrounded by lush green grass, featuring four wicker chairs with colorful cushions positioned around a glass table. A large patterned outdoor rug adds structure to the space, complemented by a potted flowering plant resting on the ground.

4.75 out of 5 average rating, 4 reviews

The Flamingo Guesthouse on CANAL

Casual, Cozy guesthouse situated on a beautiful canal looking out to the Caloosahatchee River. Deep canal with turn around that can accommodate almost any size boat. Quiet location on a dead end lane...close to grocery stores and restaurants. 45 min from Fort Myers Beach! Window air in bedroom. ceiling fans. I bedroom with King bed. Daybed in Entry living area. Full kitchen and wifi. Covered Carport to keep your car cool from the sun Deck out back to relax and watch the world float by!