
Guesthouse holiday rentals in Mesa
Find and book unique guesthouse rentals on Airbnb
Top-rated Guesthouses in Mesa
Guests agree: These guesthouses are highly rated for location, cleanliness and more.

Hidden Oasis at South Mountain!
Hidden Gem!! Take it easy at this unique and tranquil getaway. Nestled up against South Mountain, enjoy the breathtaking views in this quaint guesthouse. If you are lucky, you may see some mountain wildlife! Enjoy a freshly renovated space with light and cozy furnishings. Privately owned and managed. No bot responses. Our 100+ 5 star reviews speak for themselves. Very close to hiking trails, mountain biking, major freeways, restaurants, shopping and grocery stores. STR-2024-00443

Private studio! Central to popular locations.
Thanks for looking at the Copper State Casita. Our desert chic inspired casita is centrally located and nearby the Arcadia neighborhood. Tucked into an older neighborhood, it’s a 400 square foot studio with its own private patio. All the comforts of home in a small package. A short drive to Airport, Tempe, Scottsdale & Downtown Phoenix. Great for couples, business travel, friends, or small family. Just a few short minutes by car to trails, shopping & many popular restaurants.

Historic Firehouse Downtown Chandler Large shower
Welcome to the historic Firehouse, where you're a quick 5-minute stroll away from bustling Downtown Chandlers top-notch restaurants and bars. You're staying in a historic building that has been magically transformed into a cozy Airbnb retreat. Step Inside the Firehouse Garden with 2 stylish bedrooms that are ready to whisk you away into dreamland, 1 amazing bathroom. With enough space to accommodate up to 6 guests. This is the perfect spot for a getaway with your favorite people.

Private, Convenient Studio Apartment
Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Cozy, Private Mid-Century Casita
Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. On-site covered parking. Please no pets. This is a no-smoking property (tobacco, weed, vape).

Detached Guesthouse | Full Kitchen & Parking
Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

Cottage
Have you ever wanted to try a tiny house? The Casita is your chance! The Casita is a sparkling clean, small studio that has everything you need for your stay! The Casita is nicely located to Route 60 2miles. then to 101, 202 and I10. Mesa Convention center, Mesa Arts Center and Mesa Amphitheatre: 2 miles. ASU 8 miles. MCC 2 miles. Phoenix 19 miles. and Scottsdale 13 mi. Also many casinos, golf courses and hiking trails. Come enjoy the East Valley!

Casita/ Heated Pool, Hot Tub, Amazing Amenities
Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Sanitized Spacious Desert Getaway
Newly built guest house in Northeast Mesa. Spacious Living and Kitchen area. 10 foot ceilings. Quite Neighborhood. Right around the corner from Usery Park, Hiking, biking and equestrian trails. Down the road form the Superstition Mountains. 25 minute drive to Saguaro or Canyon Lake. 15 minutes to the Salt River. Quick and easy assess to the Loop 202. Just minutes away from the Superstition Springs Mall.

Private-Detached Guesthouse & Zen Courtyard
Discover the perfect desert escape in our charming, detached casita. Tucked away in one of Chandler’s most peaceful and established neighborhoods, this private guest house offers a level of tranquility that is hard to find. Whether you are visiting for a focused business trip, a solo retreat, or a romantic weekend, you will find this space to be an intentional sanctuary designed for rest and rejuvenation.

Poolside Casita | Goats & Alpacas | Urban Farm
Escape to a one-of-a-kind, mini ranch retreat in the heart of Chandler. 🌵After exploring the Sonoran desert, return to your private La Cabra Casita. 🐐 Unwind poolside, grill dinner under the desert sky, and enjoy hands-on farm fun with our friendly goats and alpacas. In the morning, wake up to the simple joy of fresh duck and chicken eggs, when available.

Mesa Casita with King Bed
Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.
Popular amenities for Mesa guesthouses
Family-Friendly guesthouses

McDowell Suite

Centrally Located Renovated Guest House

Scottsdale guest suite

Private Casita

Cozy casita in a beautiful setting

Scottsdale Luxury Guesthouse

Our Guest House at Papago Park

Unique urban habitat near ASU/downtown Tempe
Guesthouses with a patio

Luxe Historic Casita w/ Free Parking: Casa Pascual

Ruby's Hideaway, a historic red brick studio.

Scottsdale Casita at Lincoln Rd

Charming & spacious Casita! Like home only better!

Entire Private Guest House with King Master

Modern Charming Studio: Prime Location & Top Value

Beautiful little house

The White Barn @ Freedom Farms
Guest house rentals with a washing machine and dryer

Adorable Willo Cottage in Historic Central Phoenix

Best Little Guesthouse in Melrose !

The Casita in Tempe Arizona

NEW Stylishly Designed Casita Steps from DTPHX

Studio B industrial design

Private and Quiet - 1 bdrm/1 bath Casita

Hubbell Hideaway House by Downtown Phoenix

Guesthouse in city's most walkable neighborhood
Quick stats about guesthouse rentals in Mesa

Total holiday rentals
Explore 150 holiday rentals in Mesa

Nightly prices starting at
Mesa holiday rentals start at $68 NZD per night before taxes and fees

Verified guest reviews
Over 13,390 verified reviews to help you choose

Family-friendly holiday rentals
20 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 30 rentals that welcome pets

Holiday rentals with a pool
50 properties feature pools

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wi-Fi availability
150 of Mesa holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Mesa rentals

4.9 Average rating
Mesa stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium
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- Phoenix Convention Center
- Chase Field
- Lake Pleasant
- TPC Scottsdale - Champions Course
- Grayhawk Golf Club
- The Westin Kierland Golf Club
- Salt River Fields at Talking Stick
- WestWorld of Scottsdale
- Peoria Sports Complex
- Sloan Park
- Grand Canyon University
- Surprise Stadium
- Tempe Beach Park
- State Farm Stadium
- Goodyear Ballpark
- Desert Diamond Arena
- Scottsdale Stadium
- Arizona State University
- Salt River Tubing
- Footprint Center
- Camelback Ranch
- We-Ko-Pa Golf Club
- Papago Park
- Hurricane Harbor Phoenix
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