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Guesthouse holiday rentals in Mesa

Find and book unique guesthouse rentals on Airbnb

Top-rated Guesthouses in Mesa

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Top Guest favourite
A private patio area is shown with a round dining table surrounded by comfortable chairs. A grill is positioned nearby, and soft lighting is present overhead. The view extends to gentle hills and desert vegetation, with a wooden fence adding to the serene setting.
Guesthouse in South Mountain
4.98 out of 5 average rating, 176 reviews

Hidden Oasis at South Mountain!

Hidden Gem!! Take it easy at this unique and tranquil getaway. Nestled up against South Mountain, enjoy the breathtaking views in this quaint guesthouse. If you are lucky, you may see some mountain wildlife! Enjoy a freshly renovated space with light and cozy furnishings. Privately owned and managed. No bot responses. Our 100+ 5 star reviews speak for themselves. Very close to hiking trails, mountain biking, major freeways, restaurants, shopping and grocery stores. STR-2024-00443

Top Guest favourite
Guesthouse in Camelback East
4.98 out of 5 average rating, 1,150 reviews

Private studio! Central to popular locations.

Thanks for looking at the Copper State Casita. Our desert chic inspired casita is centrally located and nearby the Arcadia neighborhood. Tucked into an older neighborhood, it’s a 400 square foot studio with its own private patio. All the comforts of home in a small package. A short drive to Airport, Tempe, Scottsdale & Downtown Phoenix. Great for couples, business travel, friends, or small family. Just a few short minutes by car to trails, shopping & many popular restaurants.

Top Guest favourite
Guesthouse in Chandler
4.92 out of 5 average rating, 162 reviews

Historic Firehouse Downtown Chandler Large shower

Welcome to the historic Firehouse, where you're a quick 5-minute stroll away from bustling Downtown Chandlers top-notch restaurants and bars. You're staying in a historic building that has been magically transformed into a cozy Airbnb retreat. Step Inside the Firehouse Garden with 2 stylish bedrooms that are ready to whisk you away into dreamland, 1 amazing bathroom. With enough space to accommodate up to 6 guests. This is the perfect spot for a getaway with your favorite people.

Top Guest favourite
A clear pathway leads to a private entrance illuminated by warm lights along the fence. The exterior features a white wall and a simple door framed by a light-colored overhang. A serene sunset adds a colorful backdrop to the tranquil scene.
Guesthouse in Mesa
4.98 out of 5 average rating, 301 reviews

Private, Convenient Studio Apartment

Discover the perfect blend of location and comfort in our newly renovated studio apartment. Nestled centrally between Mesa, Scottsdale, and Tempe, you're at the heart of abundant dining choices, shopping convenience, and grocery store accessibility. Just 15 minutes from Sky Harbor and a swift 30 minutes from Mesa Gateway, your travels are a breeze. Enjoy total privacy with your exclusive entrance, ensuring a tranquil, personal escape in the midst of the city's best offerings.

Guest favourite
A spacious bedroom is highlighted by natural light from a door leading outside. The room features a queen size bed covered with a blue striped comforter, flanked by two bedside tables with lamps. Framed artwork adorns the walls, adding character to the space.
Guesthouse in Mesa
4.94 out of 5 average rating, 312 reviews

Cozy, Private Mid-Century Casita

Enjoy your stay in the Valley of the Sun at this 350 sq. ft. stand-alone private casita with full bathroom & kitchenette. The bedroom features incredible natural light, but also the ability to block it out if you wish. Rest easy on the comfortable queen size bed and catch up on your favorite shows on the HD smart TV. WiFi is available, & for business travelers there is a laptop desk. On-site covered parking. Please no pets. This is a no-smoking property (tobacco, weed, vape).

Superhost
A bright living area is presented with a comfortable sectional sofa and accent chairs in various shades of grey and teal. A television is positioned on a stylish media console, while a decorative area rug adds color beneath a coffee table. Natural light filters through the window.
Guesthouse in East Mesa
4.93 out of 5 average rating, 199 reviews

Detached Guesthouse | Full Kitchen & Parking

Enjoy our newly remodeled and professionally designed 1 bed, 1 bath private guesthouse. The stylish and cozy suite includes a full kitchen with brand new appliances, a work space, living room, and bedroom with a closet and ensuite bathroom. It is located just 15 mins away from major destinations, such as ASU, Sky Harbor International Airport, and fun attractions. We offer free parking on the property, in addition to wi-fi, Roku TV and toiletries. We would love to host you!

Guest favourite
The kitchen features wooden cabinetry and a patterned tile backsplash. Included are a stove, microwave, and refrigerator. A coffee maker is positioned on the counter, and a decorative red rug is laid in front of the sink. Natural light enters through a window adorned with red curtains.
Guesthouse in East Mesa
4.89 out of 5 average rating, 524 reviews

Cottage

Have you ever wanted to try a tiny house? The Casita is your chance! The Casita is a sparkling clean, small studio that has everything you need for your stay! The Casita is nicely located to Route 60 2miles. then to 101, 202 and I10. Mesa Convention center, Mesa Arts Center and Mesa Amphitheatre: 2 miles. ASU 8 miles. MCC 2 miles. Phoenix 19 miles. and Scottsdale 13 mi. Also many casinos, golf courses and hiking trails. Come enjoy the East Valley!

Top Guest favourite
Guesthouse in East Mesa
4.89 out of 5 average rating, 358 reviews

Casita/ Heated Pool, Hot Tub, Amazing Amenities

Private Casita with an amazing steam room and upscale shower. Heated large pool and hot tub along with three covered outbuildings: full outdoor kitchen with BBQ, full stove, MW, Hot Water Sink and large bar area; living room and dining room with wood burning fireplace. A full set of dishes, pots and pans are in this area for your use. Lots of private sitting areas or just hang out in the orchard and pick citrus fruit from the 40 plus trees.

Guest favourite
Guesthouse in Mesa
4.95 out of 5 average rating, 304 reviews

Sanitized Spacious Desert Getaway

Newly built guest house in Northeast Mesa. Spacious Living and Kitchen area. 10 foot ceilings. Quite Neighborhood. Right around the corner from Usery Park, Hiking, biking and equestrian trails. Down the road form the Superstition Mountains. 25 minute drive to Saguaro or Canyon Lake. 15 minutes to the Salt River. Quick and easy assess to the Loop 202. Just minutes away from the Superstition Springs Mall.

Top Guest favourite
A serene courtyard is highlighted by a decorative water feature, which is positioned in the foreground. Lush greenery and potted plants surround a pathway leading to the entrance of the private casita, creating an inviting atmosphere.
Guesthouse in Chandler
4.98 out of 5 average rating, 407 reviews

Private-Detached Guesthouse & Zen Courtyard

Discover the perfect desert escape in our charming, detached casita. Tucked away in one of Chandler’s most peaceful and established neighborhoods, this private guest house offers a level of tranquility that is hard to find. Whether you are visiting for a focused business trip, a solo retreat, or a romantic weekend, you will find this space to be an intentional sanctuary designed for rest and rejuvenation.

Top Guest favourite
The inviting pool area is surrounded by vibrant greenery and features a pergola with a dining table. Comfortable teal chairs are positioned nearby, offering relaxation by the water. The pool reflects the surrounding trees and sky, enhancing the tranquil atmosphere of the outdoor space.
Guesthouse in Chandler
4.99 out of 5 average rating, 320 reviews

Poolside Casita | Goats & Alpacas | Urban Farm

Escape to a one-of-a-kind, mini ranch retreat in the heart of Chandler. 🌵After exploring the Sonoran desert, return to your private La Cabra Casita. 🐐 Unwind poolside, grill dinner under the desert sky, and enjoy hands-on farm fun with our friendly goats and alpacas. In the morning, wake up to the simple joy of fresh duck and chicken eggs, when available.

Guest favourite
Guesthouse in East Mesa
4.96 out of 5 average rating, 573 reviews

Mesa Casita with King Bed

Casita with a king size bed and kitchenette located in a quiet Mesa neighborhood. The room is a dedicated Airbnb space in a separate building from the main house with it’s own entrance, private bath, and kitchenette perfect for a quick breakfast or a bite to eat. We are minutes from local freeways. A 15 min drive to Scottsdale, Tempe, Chandler, and Gilbert.

Popular amenities for Mesa guesthouses

Quick stats about guesthouse rentals in Mesa

  • Total holiday rentals

    Explore 150 holiday rentals in Mesa

  • Nightly prices starting at

    Mesa holiday rentals start at $68 NZD per night before taxes and fees

  • Verified guest reviews

    Over 13,390 verified reviews to help you choose

  • Family-friendly holiday rentals

    20 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 30 rentals that welcome pets

  • Holiday rentals with a pool

    50 properties feature pools

  • Rentals with dedicated workspaces

    80 properties have a dedicated workspace

  • Wi-Fi availability

    150 of Mesa holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mesa rentals

  • 4.9 Average rating

    Mesa stays are highly rated by guests—averaging 4.9 out of 5!

  • Nearby attractions

    Mesa's top spots, include Sloan Park, Golfland Sunsplash, and Hohokam Stadium

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