
Holiday houses in Panama Canal
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Panama Canal
Guests agree: these stays are highly rated for location, cleanliness and more.

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Spectacular Duplex penthouse in Panama's historic district, 265 M2 with balconies, private outdoor terraces, an interior garden living room, a dining room, 3 bedrooms (+ sofa bed in studio), recently renovated with a Loft concept, exclusive unique and comfortable design, in the best area of the historic district, perfect for relaxing and unwinding, kitchen, dishwasher, living room with washing machine, shared pool, elevator, 24-7 doorman, children who cannot swim are not allowed, a wide variety of leisure activities in the area.
LocationFamilyAmenities

Casa Condal - Your Luxury Retreat in Cerro Azul
Birdwatching • Romantic Getaway • Remote Work Escape the city. Breathe pure mountain air. Reconnect with nature. Casa Condal - private, modern, sustainable and regenerative hospitality inside Chagres National Park WiFi 65" Smart TV. Sound Bar Self check-in Private parking Fully equipped kitchen 220mts. private trail Deck-Mirador + FirePit, panoramic view of the mountains and valley King bed + Full size sofa bed BBQ Wheelchair accessible 40 min from Tocumen Airport. 1 hr from Panama city.
FamilyLocationParks

Peaceful Stay in the Heart of Casco
Enjoy a quiet and comfortable apartment in the center of Casco Viejo. It’s a great place to relax after walking around the neighborhood, with everything you need for a nice stay. Restaurants, cafés, and main attractions are just a short walk away. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.
FamilyLocationView

Panoramic Casco Viejo Lookout in The Sands
exquisite apartment blends cozy comfort with sophisticated luxury. Every detail radiates elegance, from the plush, high-end furnishings to the warm, inviting ambiance. The open-concept living area is perfect for relaxing or entertaining, with breathtaking views of the UNESCO World Heritage Casco Viejo framing the horizon. The compact kitchen has modern appliances, sleek countertops, and all essentials. With Casco Viejo vistas, this stylish retreat is perfect for exploring culture and history.
LocationValueSleep quality

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
FamilyValueIndoor spaces

Canal Studio
Ground floor apartment, ideal for groups who love good taste, jungle landscapes and confort. Near the apartment there are paths to the Panama Canal, hills and jungle. Enjoy the elegance, nature and history of the Panama Canal with your family and friends in a jungle environment, quiet and very confortable. Ground floor apartment, ideal for groups who love good taste, jungle landscapes and comfort. Near the apartment there are paths to the Panama Canal, hills and jungle.
ValueFamilyTV

Walk to Everything | Luxury Stay in Casco Viej
Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.
ValueLocationBathroom

Casco Antiguo Apartment with Balcony & Stone Wall
Elegant apartment in the heart of the Historic District. Enjoy a colonial-style space with exposed stone walls, warm lighting, and a charming balcony overlooking vibrant streets. Located on Avenida B, within walking distance of restaurants, coffee shops, rooftop bars, and historic sites. Sleeps up to 5 guests. Perfect for experiencing the culture and energy of Casco Viejo. Due to the lively atmosphere in the area, noise may be heard at night on weekends.
ValueFamilyCheckout

Tropical Haven with Pickleball/Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.
FamilyLocationBackyard

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.
LocationFamilyIndoor spaces

Most Beautiful Loft in the Heart of Casco Viejo
Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.
ValueLocationLaundry

BirdHouse — Gamboa, Panama Canal Rainforest
BirdHouse: Let's inhabit the space. Designed for people who want to experience the tropics, not shut them out. Open the screens, feel the breeze, listen to the rain, cool off in the pool, and wake to birds and howler monkeys. Located in historic Gamboa, BirdHouse is a place to slow down and experience one of the world’s richest tropical forests from the comfort of a thoughtfully designed home.
LocationValueAccess
Popular amenities for Panama Canal holiday rentals
Other great holiday rentals in Panama Canal

The Crystal House: Luxury Modern Wood Cabin
LocationFamilyBathroom

The Bird's Nest in the Clouds
LocationFamilySleep quality

Gorgeous Flat in the best location in Casco Viejo
ValueFamilyHospitality

Private parking & rooftop | Studio Casco Center
ValueLocationAir conditioning

Luxury Oceanfront Resort 22nd Floor View, 200°
FamilyLocationView

The Hidden Gem
FamilyLocationGetting around

Moon House River Dreams Cerro Azul
LocationFamilyAccuracy

Luxury apt in Panama City 2 Rooms 3 Baths
FamilyValueCheck-in
Destinations to explore
- Hostel rentals Panama Canal
- Rentals with breakfast Panama Canal
- Loft rentals Panama Canal
- Family-friendly rentals Panama Canal
- Guesthouse rentals Panama Canal
- Condo rentals Panama Canal
- Serviced apartment rentals Panama Canal
- Rentals with a sauna Panama Canal
- Waterfront rentals Panama Canal
- Bed and breakfasts Panama Canal
- Hotel rooms Panama Canal
- Rentals with pools Panama Canal
- Rentals with an accessible height bed Panama Canal
- Private suite rentals Panama Canal
- Apartment rentals Panama Canal
- Pet-friendly rentals Panama Canal
- Boutique hotels Panama Canal
- Rentals with beach access Panama Canal
- Beachfront rentals Panama Canal
- Rentals with a kayak Panama Canal
- Rentals with lake access Panama Canal
- House rentals Panama Canal
- Rentals with a hot tub Panama Canal
- Townhouse rentals Panama Canal
- Things to do Panama Canal
- Sightseeing Panama Canal
- Tours Panama Canal
- Art and culture Panama Canal
- Food and drink Panama Canal
- Nature and outdoors Panama Canal
- Sports activities Panama Canal
- Things to do Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Tours Panama
- Food and drink Panama
- Art and culture Panama





