
Guesthouse holiday rentals in Pima County
Find and book unique guesthouse rentals on Airbnb
Top-rated Guesthouses in Pima County
Guests agree: These guesthouses are highly rated for location, cleanliness and more.

RetroTrek Bungalow Private-Fenced-Cozy
Our bungalow is nicely suited for 2, features a separate kitchen, a 3/4 bath, & large main room for sleeping or relaxing. We offer a private entrance with carport parking. Yard is fenced, with dog door, up to 2pets are welcome. Centrally located, within minutes of the airport, downtown and the University of Arizona. We are within walking distance to Reid Park for golfing or a visit to the Zoo. Even though we are midtown with easy access to many areas of town, you will find it surprisingly quiet.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in a hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies. Lounge by the pool in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Peaceful Desert Oasis in Central Tucson Foothills
Newly renovated guest home located in a quiet central area in the Catalina Foothills. Trails and biking in our backyard, 10-15 min drive to hiking/parks, downtown and UofA! Away from everything and yet conveniently close to everything! Enjoy beautiful mountain views and professional landscaping. Well equipped kitchen with washer/dryer and a cozy fireplace and desk in the master bedroom. Lots of privacy from the main home. Stocked with all your amenities needed for a cozy and comfortable stay.

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Tranquil Bears Path Casita
This Property is truly a unique oasis in the desert! It is one of the few urban areas in Tucson that offers you the best of both worlds! A place to come home to and enjoy the quiet nights, plentiful stars, and walks among the the numerous Saguaros, Mesquite and Desert Pine trees. All while being right in the heart of Tucson's East side just minutes from shopping and restaurants! Our extraordinary place is close to Mt Lemon, Sabino Canyon, hiking, running, biking trails and riding stables.

Dream House
Replenish * Re-calibrate * Reconnect.. Welcome to our little house of dreams! You have found the perfect leaping off point to explore all this region has to offer. Nestled snugly between the Patagonia and Santa Rita mountains, our casita sits at just under 5,000 ft, making it temperature perfect almost year round. Enjoy our 38 acres and private hiking trails right out the front door with endless possibilities for adventure. Recharge, Rejuvenate, and Revel in our cozy, clean, quite space.

Time Capsule in the Sonoran Desert
The Time Capsule is a unique experience in a space age module dropped in the middle of an 11 acres desert sanctuary and sculpture park, adjacent to the Saguaro National Park. Enjoy the quietness of the desert in a safe environment located at just 35 minutes from downtown Tucson. Because of the refinement of the interior design, we cannot accept any pets in the Time Capsule. However, service animals are welcome. Please note that check-in is in-person only and not later than 10:00 PM.

Cozy Mountain Retreat w/ Hot Tub
Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Attractive Casita In Tucson
A charming getaway casita with stunning views of the majestic Saguaro National Park and the Picture Rock Mountains for spectacular sunsets. The 5-acre site is home to many varieties of cacti, including giant saguaros and other native plants and trees. Through the casita's panoramic windows, you can observe desert vegetation, birds, rabbits, coyotes, bobcats, javelinas, and deer. An evening bath in the jacuzzi under the starry sky will certainly remain in your memory for a long time.

The Coop- Luxury guest house with ideal location
This luxury guest home was originally a chicken coop for a farmer over 60 years who owned the majority of the land in the area. With an addition and a complete renovation, we have designed this for the perfect vacation rental ideally located in Tucson. 15 minutes to Banner and the U of A. 10 minutes to Oro Valley or the freeway. The stylish guest home is separated from our home and designed with privacy in mind. Enjoy this brand new house for your stay with experienced hosts.

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Saguaro Oasis Retreat near National Park
If you love nature this casita is just for you. Located 15 minutes from downtown and only a few minutes from stunning hiking and mountain biking trails in the National Park. The property is very much like a botanical garden with fruit trees filling up the back and a wide variety of succulents filling the front. The casita has its own private porch while the property shares two large communal patios with outdoor dining and a fire pit.
Popular amenities for Pima County guesthouses
Family-Friendly guesthouses

Casita de Pomona

4th Ave & University - Pool + Hot Tub + Garage!

Cozy midtown guesthouse

Charming Private Oasis Casita with Pool & Hot Tub

Charming, Cozy Casita with Pool - low summer rates

Rustic Cabin with Mountain Views Close to Wineries

Guest Casita

Charming Indoor Jacuzzi & outdoor heated pool
Guesthouses with a patio

Guest Cottage located near University and Downtown

*Prime Location: King Suite Guest House!*

Cute eco-built guesthouse

Southwest Solitude

Midtown House near TMC & UofA•Fast WiFi •Self ChIn

Central Casita Minutes from UA & Downtown

Casita Chapulin

Amazing Casita at the Tubac Resort-Self check-in*
Guest house rentals with a washing machine and dryer

Solar Powered Guest House Near UA—No Cleaning Fee!

Studio in the Saguaro Forest

Oasis: Casita Colibrí - Little Hummingbird House

Blue Lake Boutique Hotel

Mi Casita in Historic Downtown

Positano

Fun Retro Cottage

Cozy Casita with Private Courtyard -5 Mins to UofA
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- University of Arizona
- Arizona-Sonora Desert Museum
- Reid Park Zoo
- Tucson Botanical Gardens
- Tumamoc Hill
- Titan Missile Museum
- Mission San Xavier del Bac
- Tucson Convention Center
- Tucson Museum of Art
- Pima Air & Space Museum
- Rialto Theatre
- Children's Museum Tucson
- Tumacacori National Historical Park
- Mini Time Machine Museum of Miniatures
- Trail Dust Town
- Gene C Reid Park
- Mercado San Agustín
- Tubac Presidio State Historic Park
- Tucson Mountain Park
- Rooster Cogburn Ostrich Ranch
- Picacho Peak State Park
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