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Holiday houses in Rio Sereno

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Rio Sereno

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Home in San Vito

Private 40-Acre Hacienda Estate

Our Hacienda sits on 40 Acres of land that was once one of the areas original Coffee plantations. Today, it is a private Estate with big jungle trees, about 4km of trails, fruit orchards and beautiful gardens. The house has been fully renovated and is welcoming and comfortable. A large wrap-around terrace looks out toward Volcán Barú and La Amistad Park. Hacienda Viva offers a setting to slow down and reconnect. Our place offers something for everyone..a perfect place to enjoy and make Memories!

5.0 out of 5 average rating, 13 reviews
Superhost
A shaded outdoor patio features a suspended hammock surrounded by lush greenery and vibrant vegetation. A wooden table is positioned beside the hammock, offering a serene space for relaxation. The distant mountains can be seen in the background, framed by the vibrant plant life.
Home in Las Brisas

Casa el Guarumo

Casa El Guarumo sits at the top of our 4-acre permaculture farm, situated between Parque Internacional La Amistad and the town of San Vito, Coto Brus. Come to reset and unwind. Take in the beautiful mountain views, clean air, and pure water. Enjoy fresh fruit, coffee, and handcrafted chocolate from the farm. Adventure to nearby waterfalls and hot springs, hike the farm trails to the creek, or drift off in a hammock to the songs of the myriad of bird species that can be observed in our area.

4.95 out of 5 average rating, 19 reviews
Top Guest favourite
Home in Zancudo

Oasis on the beach| Private Pool | AC

Tucked away in the safe, idyllic tropical rainforest of Costa Rica’s South Pacific Coast, where lush green jungle meets the bright blue Pacific. One of the most biologically diverse regions on Earth, it’s home to Zancudo: a sleepy, off-the-beaten-path fishing village happily untouched by mass tourism. Zancudo delivers all the creature comforts, sodas, grocery shops, bars, local eateries, tours, and plenty to do - making it perfect for adventurers, digital nomads, couples, and families alike.

4.98 out of 5 average rating, 130 reviews
Top Guest favourite
The entrance features a light blue door adorned with a seasonal wreath, accompanied by a welcoming porch. Two white vintage-style chairs are situated on the porch, surrounded by potted plants and flowers. A decorative stone pathway leads to the entrance, framed by greenery.
Cottage in Volcan

Casa Dolly– Cozy Rural Cottage Close to Downtown

Unwind at Casa Dolly— a cozy renovated cottage on a 15,000 sq ft garden in Volcán, Chiriquí. Sleeps 8 (2 indoor bedrooms + 1 separate shed bedroom). Fully equipped kitchen, flat‑screen TV (cable + streaming), washer, dryer, hot water, and 400 Mbps fiber Wi‑Fi — ideal for remote work. Enjoy multiple outdoor seating areas, fruit trees, a small chicken coop, a secure fenced yard, and free on‑site parking. Five blocks (10-minute walk) to Main Street — perfect for families and nature lovers.

4.92 out of 5 average rating, 142 reviews
Guest favourite
A modern two-story house is displayed with a light-colored exterior and a red roof. Large windows are seen throughout, enhancing natural light inside. A gravel pathway leads to the entrance, bordered by lush greenery and flowering plants, providing a serene and inviting approach.
Home in Aguabuena

Casa Arzú San Vito Coto Brus

Ubicada a 1:00 de Paso Canoas Casa ARZÚ ubicada en Santa Cecilia de Agua Buena, Coto Brus. Es un lugar lleno de paz, rodeado de naturaleza, excelentes vistas, entre ellas hacia el Volcán Barú y comunidades aledañas. Clima fresco. Es espaciosa, privada y cuenta con las comodidades necesarias para una estancia agradable y satisfactoria. Ideal para desconectarte del afán diario. Para disfrutar de estas hermosas vistas, tendrás que transitar como 7 minutos en camino lastre.

4.96 out of 5 average rating, 23 reviews
Guest favourite
Home in Golfito

New! Romantic-Private-Incredible views-Luxury

Most luxurious one bedroom home in Golfito Completed May 2026 Escape to a private modern villa surrounded by lush jungle with beautiful Gulf views. This secluded retreat features a large private pool, spacious indoor-outdoor living, and a fully equipped kitchen. Floor-to-ceiling windows bring nature inside, while AC, high-speed internet, and a large TV provide comfort. Perfect for couples seeking privacy, wildlife, and easy access to Golfito, Corcovado, and nearby beaches.

5.0 out of 5 average rating, 9 reviews
Top Guest favourite
Loft in Coto Brus

Ecoluma 1: Acogedor estudio con jardín en Sabalito

Bienvenidos a nuestro encantador estudio en Sabalito de Coto Brus. Este espacio ofrece la combinación perfecta entre la tranquilidad natural y la conveniencia de estar cerca del centro del pueblo. Además, estamos a 10 min de la frontera de La Unión y Río Sereno, a 1hr de Paso Canoas y 1.30hrs del Depósito Libre Golfito. Ideal para parejas, viajeros en solitario o profesionales que buscan un retiro tranquilo en la zona de Coto Brus. Contamos con factura electrónica.

4.97 out of 5 average rating, 32 reviews
Superhost
Cabin in Paraiso

Best alpine cabin with jacuzzi and amazing weather

Alpine cabin located between Boquete and Volcán. Set in a very peaceful area and fully equipped so you can enjoy an amazing vacation. It features a terrace and a balcony with views of Volcán Barú and the ocean. It also has a hot-water jacuzzi so you can take relaxation to the next level. Paraíso is known for its excellent climate, rivers, lush vegetation, canopy tours, and hiking trails so you can make the most of your stay.

4.8 out of 5 average rating, 55 reviews
Top Guest favourite
A private deck features two modern chairs with a small table between them, positioned on a textured area rug. A custom-built jacuzzi is visible in the background, surrounded by a wooden railing. Natural light floods the indoor living area through expansive glass doors.
Cabin in Boquete

Mundo Novo Casita @ Finca Panda

Mundo Novo is one of our new, one-room casitas and has one of the most incredible views on the property. Perfect for couples, singles or family with a small child, Geisha sleeps 2 people comfortably in one king bed (maximum 3 guests when using sofa). Geisha was designed with every amenity needed to have a perfect and relaxing stay. Custom-built jacuzzi, fire-pit, kitchen, incredible shower, high-speed WiFi and more

5.0 out of 5 average rating, 11 reviews
Guest favourite
A quaint cabin is elevated on stilts, surrounded by lush greenery and vibrant plants. The structure features a simple design with a sloped roof and a small balcony, offering a peaceful retreat in nature.
Cabin in Coto Brus

Hospedaje El Paraíso

Hospedate en un lugar tranquilo rodeado de naturaleza, ideal para descansar y desconectarte de la rutina diaria. Está cerca del Parque La Amistad, cerca de la frontera con Panamá (La Unión, Rio Sereno y Paso Canoas) Jardín Botánico Las Cruces, Finca Ecológica Cántaros y otros atractivos de la zona. Acceso con cualquier tipo de vehículo, el parqueo es muy amplio. La cabaña está totalmente equipada.

5.0 out of 5 average rating, 10 reviews
Guest favourite
A vibrant blue cabin is nestled among lush tropical plants, surrounded by tall palms and dense greenery. The elevated structure features a deck with chairs, offering an inviting outdoor space while maintaining privacy within the natural landscape.
Cabin in Zancudo

Stunning beach front cabin w/ wifi

Our cabin, called the Resting Dragon, has 250 feet (75 meters) of beach front property, offering gorgeous views and complete privacy. Perfect for a relaxing vacation with all amenities available: full kitchen, living room, queen bed and sofa bed, large deck and 10mbs high speed internet to facilitate teleworking and video conference calls.

4.81 out of 5 average rating, 72 reviews
Superhost
Houseboat in Cuesta de Piedra

Amanecer Frente al Majestuoso Volcán Baru

Despierta con una de las vistas más Espectaculares de Panamá.🌿 Relajate y Desconecta con sus altos techos te da una vista "Privilegiada"al majestuoso Volcán Barú, perfecta para familiares y amigos que quieren escapar de la ciudad Envíanos un mensaje si quieres saber más o tienes alguna pregunta 👌😉

4.56 out of 5 average rating, 9 reviews

Popular amenities for Rio Sereno holiday rentals