Holiday houses in San Lorenzo District

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in San Lorenzo District

Guests agree: these stays are highly rated for location, cleanliness and more.

1 of 1 pages1 / 1

Top Guest favourite

A spacious living area features a comfortable sofa and two accent chairs surrounding a striped area rug. Floor-to-ceiling windows offer panoramic views of the ocean and surrounding islands, while a flat-screen TV is positioned on a low console for easy viewing.

Villa in Boca Chica

Sand Dollar Villa by the sea at Boca Chica Panama

Sand Dollar Villa by the sea This beautiful, very private retreat boasts panoramic views and direct access to a beautiful beach and sheltered bay. Located in Boca Chica, it is only 45 minutes from Panama’s second largest city, David. From your doorstep, you can enjoy island hopping in an archipelago of unexplored islands, or you can choose to soak in the sun on your very own private beach. Sand Dollar Villa offers the perfect décor for gracious living and entertaining in a magical setting!

FamilyLocationAccuracy

4.95 out of 5 average rating, 112 reviews

Top Guest favourite

A private outdoor area features a pool surrounded by stone tiles and a covered seating area. Sun loungers are positioned under an umbrella, with views of green landscape and water in the background. The setting provides a serene atmosphere for relaxation.

Home in Playa Hermosa

Entire house with private pool facing beach !

Astonishing views, bird sounds & howler monkeys, Our region is designated by Panama as a Natural Water Preserve with 23 islands, lots of snorkeling, whale watching and beachcombing! One of the top best sport fishing destinations in the world! Casa Tanamera has a large garden set amidst the jungle. it boasts a plunging view on the beach and its entire bay area. the house is large enough for 4 persons, has large bedrooms and bathroom, a large patio with its dining, BBQ and lounge area.

FamilyLocationAccess

5.0 out of 5 average rating, 52 reviews

Guest favourite

Home in Boca Chica

Escape to your oceanfront retreat: Sea La Vie!

This stunning new home, offers a 2-bedroom, 2.5-bath main house and a separate studio casita, hosting up to six guests. Enjoy open living spaces, a gourmet kitchen, and panoramic ocean views. Solar-powered and nearly off-grid, with Starlink Wi-Fi for modern comfort. Surrounded by wildlife and waves, it’s a peaceful sanctuary where luxury meets nature.Wake to howler monkeys calling at dawn and fall asleep to the symphony of tree frogs and gentle surf. Your forever paradise in Playa Hermosa.

LocationFamilyAmenities

4.85 out of 5 average rating, 13 reviews

Top Guest favourite

Apartment in David

Large balcony | 2 bedrooms in the heart of David

Enjoy David from a modern 2-bedroom apartment designed for executives and families. Start your day with a coffee on your spacious balcony, relax with a movie in the cozy room, or just a hike to get to know the city. With a strategic location 2 minutes by car from the Via Interamericana and Plaza Terronal and 5 minutes from Federal Mall. Close to restaurants, plazas and shops, with easy connection to Boquete, Cerro Punta, the border with Costa Rica and other Chiriquí destinations.

LocationSleep qualityView

5.0 out of 5 average rating, 9 reviews

Guest favourite

A round wooden dining table is set for four, surrounded by light-colored chairs. A chandelier hangs above, casting a warm glow. Light enters through open doors, highlighting wall art and plants, creating a welcoming dining space.

Casa particular in Dolega District

Wanakaset Forest Haven 2BR, River & shared Pool

(Minimum 2 nights) Casa Quetzal is a serene 2-bedroom retreat nestled in the lush forest of Wanakaset Panama, perfect for up to 4 guests. With its open-plan living space, modern bathrooms, and fully equipped kitchen, it offers comfort in a natural setting. Relax on the private terrace or enjoy the shared pool, just a short walk away. Surrounded by rivers and tropical greenery, it’s an ideal escape for nature lovers seeking tranquility and a peaceful getaway.

LocationKitchenComfort

5.0 out of 5 average rating, 10 reviews

Top Guest favourite

A spacious room is visible through an open door, featuring a double bed with clean linens and a simple design. Natural light illuminates the area. A handcrafted wooden bench is placed in front of the bed. A potted palm adds a touch of greenery to the setting.

Guest suite in David

CasaMonèt

Suite with separate entrance: covered parking, double bed, bathroom, kitchenette and desk. Your personal space in the heart of David. It has split air conditioning, a ceiling fan, a TV with Netflix access, free WiFi internet, blackout curtains, a water reserve tank, hot water, a kitchenette equipped with an electric stove, a refrigerator, a coffee maker, a microwave, and basic utensils. It does not have a laundry room, electric generator, or soundproofing.

FamilyLocationIndoor spaces

4.97 out of 5 average rating, 575 reviews

Guest favourite

Apartment in David

Escape with a panoramic view

Welcome to Escape with panoramic views, a modern and cozy apartment in Santa Cruz Tower, David. Enjoy a spectacular view from the balcony, queen size bed, air conditioning, desk, Wi-Fi, private bathroom and hot water. Located in a quiet area, but minutes from shopping malls such as Federal Mall and Plaza Terronal, restaurants, supermarkets and businesses. It also has direct access to Boquete, Chiriquí's most popular mountain destination. English or Spanish!

LocationValueAir conditioning

4.95 out of 5 average rating, 88 reviews

Top Guest favourite

A spacious bed is centered in a room with vibrant green walls. Decorative pillows are arranged neatly on the gray bedding, complemented by a bedside table with a lamp. Art featuring a flower and a hummingbird adorns the wall above the bed.

Bungalow in Boca Chica

Finca Colibri

A modern bungalow with unique views of the mangroves of Bajia de Muerte Bay, located in the heart of a nature reserve. The bungalow is very private and quiet. It's just a few minutes drive to the nearest beach. You can expect a fully equipped kitchen, a modern furnished panoramic bathroom and a very comfortable king size bed. By request we can also organize boat trips to the islands, yoga as well as horseback riding and fishing trips.

ValueLocationHiking

4.94 out of 5 average rating, 84 reviews

Superhost

The property features a spacious beachfront villa, framed by lush palm trees and open grass areas. A vibrant red roof contrasts with the white exterior, and the shimmering ocean is visible in the background, providing a serene coastal atmosphere.

Home in Playa Nanzal

Private Beachfront Getaway

Forget your worries in this spacious and serene space. Its seclusion is its charm. Escape from the busy city of David and kick back in our private beachfront property! There are little to no lights nearby, making for extraordinary sunsets/sunrises and star gazing. Whether you are a family looking to get away in the summer, a group of friends celebrating a birthday, or just looking for a break from life, this is the spot.

LocationValueAccess

4.86 out of 5 average rating, 57 reviews

Guest favourite

Home in Boca Chica

beach house: Villa Pacifica

Villa Pacifica, by far your best choice on the Pacific Ocean. constructed this year, at 30 mt from the private beach of our farm Punta Vittoria in Boca Brava island. Your own beachbar, boat dock, situated in our valley, guaranteeing your total privacy. 3 bedrooms/bath,totally equipped kitchen, large terrace, AC, fresh water pool,and elegantly decorated. A unique blend of nature, wildlife and ocean living.

LocationFamilyIndoor spaces

5.0 out of 5 average rating, 6 reviews

Top Guest favourite

A functional kitchen area is equipped with wooden cabinets and a countertop. Natural light enters through large windows adorned with sheer curtains, highlighting modern appliances including a stove, coffee maker, and refrigerator. The tiled floor complements the warm wooden tones.

Bungalow in Las Lajas

Guesthouse Buena Vista

Our guesthouse is located on the outskirts of the village of Las Lajas, surrounded by a tropical garden overlooking the surrounding mountains. All necessary facilities such as supermarket, restaurants, ice cream parlor etc. are within walking distance. Las Lajas is not only known for its long sandy beach, it also serves as a starting point for many tourist activities and tours. Contact us about it!

LocationValueBathroom

4.97 out of 5 average rating, 31 reviews

Guest favourite

A panoramic view of the tranquil water is framed by lush green islands, showcasing the natural beauty of the surrounding landscape. The foreground features a well-maintained garden with tropical vegetation, complementing the serene atmosphere of the bay.

Villa in Boca Chica

Great views near hotel facilities

Stunning bungalow villa with elevated Pacific views, large, modern open-plan kitchen and living space, spacious master bedroom and separate large dressing/closet room with queen bed. Just above Hotel Bocas del Mar with use of its pools & facilities! Parking right outside. Private yard/garden space.

FamilyValueCondition

4.94 out of 5 average rating, 126 reviews