
Holiday houses in Santa Ana
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Top-rated holiday rentals in Santa Ana
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2nd floor Beach Apartment with Amazing Views!
Enjoy beach life all year round in Panama at Uverito Beach! Go to the beach anytime you want, it is literally at your footsteps or relax in a hammock. This 2 bedroom 1 bath 2nd floor unit has all the amenities that will make your stay comfortable. Long-term rental is also available plus electricity (except long-term rental of 28 days or more you pay), you get a smart TV, unlimited bandwidth Wi-Fi internet, hot water shower, and brand new kitchen appliances to include a dishwasher.
LocationFamilyBeach

CASA EdditA ° Cozy house in Chitré
° CASA EDDITA ° Fully equipped house for your enjoyment. Spacious, cool, and cozy in one of the best-located residential areas of Chitré, close to everything: supermarkets, casinos, and a bus terminal. If you are thinking of touring Azuero, we suggest you stop at Casa Eddita, visit downtown Chitré, its handicrafts, cathedral and its variety of typical foods; from here you will be only 1:30 hr from the best beaches of Azuero in Pedasí (Playa Venao and Isla Iguana) Welcome!
LocationFamilyPets

Loft Conivan-Las Tablas
Enjoy Las Tablas as if you were at home in this spacious and comfortable full apartment. Located on the first floor. Equipped for short or long stays, with a full kitchen, cozy living room, air conditioning and WiFi, ideal for all types of travelers. Beaches, restaurants, supermarkets, and the town's main tourist attractions are just a few minutes away. Whether you're coming for a celebration, rest, or a walk, this home is the perfect starting point to enjoy Las Tablas.
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NinaHouse, spacious and cool house in Chitré.
House just for you, now with a water tank! Up to 7 people, spacious and in one of the best areas of Chitré, quiet and family-friendly, access to the pool in the social area, parks and courts, close to everything: supermarkets, casino, bus; come to Chitre and enjoy typical meals, crafts; plan your walks and visit the best beaches: Pedasi, Venao, Isla Iguana, you can work from NinaHouse with fast internet. We now have air conditioning in the living room for your comfort.
ValueFamilyTV

Private Beach Studio · Sunset & Nature Views
Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city
LocationAir conditioningQuiet

Charming and Comfortable Apartment in Las Tablas
Enjoy a premium stay in this elegant and cozy apartment in Las Tablas, designed to offer comfort, style, and tranquility. The accommodation is tastefully decorated, perfect for relaxing after a day exploring the city. Its excellent location in Las Tablas puts you close to all the points of interest, making it the perfect choice for both short and long-term stays. ✨ A comfortable, modern space with everything you need for an unforgettable experience.
ValueLocationCondition

Country House with Pool in La Enea de Guararé
Far from the capital city, come and enjoy Panamanian folklore in a rustic but cozy space, living an indigenous experience. Relax in the pool or rest in a hammock, breathe fresh air, near the sea, surrounded by spacious and natural gardens for a good walk. Close to the Port of Guararé where you can enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian skirts.
LocationFamilyCheckout

Casa Blu Central Chitre| Sleeps 6| Private Parking
Stay in a newly renovated private home in the center of Chitré with free gated parking, a large backyard, fast Wi-Fi, and space for the whole family. Walk to restaurants, supermarkets and the cathedral while enjoying the comfort of an entire home to yourselves. It combines comfort, spaciousness, and natural light in every corner — perfect for families or groups of friends looking for a place that feels just like home.
LocationFamilyHospitality

Our Happy Place
Relax with the whole family in this quiet place to stay. It is a single-family residence, in the master bedroom we have a Queen bed (1.50 m x 1.90 m) in the second bedroom we have 2 Twin beds (90 m x 1.90 m). The residence can comfortably accommodate 4 people, however we have a sofa bed and a Pee bed available for 2 additional people. Check the small extra cost for additional people.
ValueLocationAccuracy

Colonial House in Parita
Discover the charm of Parita from a comfortable and spacious home, perfect for large groups. Located in the picturesque and peaceful town of Parita, in the Herrera Province, just 12 minutes from Chitré, this spacious home is the ideal place to immerse yourself in the history and culture of a historic colonial-era town.
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Victoria Apartment #2
In Victoria Apartment No. 2 You will find a quiet accommodation very close to the Church and Simón Bolívar Park, places where the different and renowned festivals of Villa de Los Santos are concentrated. You will also find a lot of comfort with good internet, which makes it a place to enjoy as a family or for work.
LocationValueQuiet

Spacious house in Villa de los Santos
Comfortable family accommodation in La Villa de Los Santos, with Wi-Fi, A/C, equipped kitchen, patio and parking. Located near supermarkets and plazas. Only 15 minutes from El Rompió and Monagre, 45 minutes from Isla Iguana and 1h 30 minutes from Playa Venao.
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Popular amenities for Santa Ana holiday rentals
Other great holiday rentals in Santa Ana

Family home for 8 | 3 bedrooms with A/C
LocationValueIndoor spaces

Chitré Oasis: Modern Home with Private Pool & BBQ
ValueLocationCleanliness

Arena’s Village.
FamilyComfortNearby

Enjoy a beach house facing the ocean, patio
FamilyLocationCleanliness

Farmhouse
LocationFamilyPool

Country House in Monagre de Los Santos
LocationFamilyQuiet

Country House Like in the City / La Casita
FamilyValueKitchen

La Casita 29 de las Villas de San Jose
FamilyLocationCleanliness
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