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Holiday houses in Santa Clara, Panama City

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Top-rated holiday rentals in Santa Clara, Panama City

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top Guest favourite
Apartment in Panamá
4.94 out of 5 average rating, 108 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Guest favourite
A serene bedroom is presented, featuring a spacious bed with crisp white bedding. Nightstands with lamps provide gentle lighting beside the bed. A wooden accent wall adds warmth to the space, while an organized closet and shelving unit offer functional storage.
Apartment in Panamá
4.97 out of 5 average rating, 37 reviews

5MINUTOSCOSTADELESTEwifi6-tvstreaming

BIENVENID@! disfruta de la sencillez de este alojamiento tranquilo y céntrico. El apartaestudio es ideal para esas personas que quieren conocer la ciudad y también para el que viene por trabajo,ya que tiene su escritorio y su comodidad,esta cerca de plaza de comidas,supermercados,gym,etc. queda cerca a algunos lugares turísticos,como costa del este centro de negocios,malecón,Panamá Viejo.. te puedo horientar para sitios turísticos si necesitas carro en alquiler también tenemos esa opción 😇

Guest favourite
A cozy living area features a brown sectional sofa with a soft blanket draped over the arm. Two floral artworks adorn the walls, and a small dining table with two chairs is positioned near a window, allowing natural light to enter the space.
Condo in Panama City
4.82 out of 5 average rating, 34 reviews

Home Away From Home. 15min from Airport!

Welcome to your perfect getaway! Our apartment is conveniently located just 15-20 minutes from the airport and 30 minutes from Casco Viejo. Enjoy easy access to supermarkets, malls, restaurants and more, all within a short drive. With two bedrooms, including a master bedroom with a TV and a large bed, and a second bedroom with a twin bed and a desk, you can comfortably mix business with pleasure. Book now and make yourself at home! You have the ENTIRE place to yourself. Message me!

Guest favourite
A modern living space features a flat-screen TV mounted on a textured wall, paired with a stylish coffee table and a floor lamp. Soft natural light filters through sheer curtains, illuminating the adjacent bedroom, which contains a cozy bed and bedside tables.
Apartment in Panamá
4.97 out of 5 average rating, 33 reviews

Beauty Balcony •Remote Working • Near Multiplaza

➤ Stylish and beautiful apartment, tailored for remote workers with balcony, minutes away from Multiplaza Mall . ★ Perfect for Remote Workers, desktop and 150 MB speed internet. ★ Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes & Shopping ➤ Urban Escape - Building Highlights: ★ Gym ★ 2 Co-Working Space with 500 MB speed internet ★ Pool on the Rooftop Terrace ➤ Located in San Francisco: Explore the City Easily | Uber-Friendly

Superhost
Guesthouse in Panama City
4.88 out of 5 average rating, 248 reviews

Boho Studio - Private Terrace 9 km from the airport

Perfecto para 1–2 huéspedes, Wifi, Terraza tranquila, cuarto independiente, cuenta con A/C , y su baño pequeño. Ubicado cerca del Aeropuerto Internacional de Tocumen, de 10 a 13 minutos en auto. El Studio está Cerca de 2 Centros Comerciales, Metromall y Los Pueblos OUTLET. La zona residencial es segura al caminar, calles organizadas y limpias. Tenemos la estación del Metro de Cerro Viento afuera en Metromall.

Guest favourite
Apartment in Panamá
4.99 out of 5 average rating, 138 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Guest favourite
A modern living room is depicted, featuring a wall-mounted television above a black media console. Two light-colored armchairs are positioned beside a round coffee table, which is adorned with decorative items. A large window allows natural light and offers views of the surrounding area.
Apartment in Costa del Este
5 out of 5 average rating, 9 reviews

1bd/2Bthrm East Coast-Panama

What are you waiting for to get to know and enjoy Panama? Stay in our modern, furnished and quiet apartment in Costa del Este, where you can enjoy a spectacular view, fast Wi-Fi, a fully equipped kitchen, access to the pool on the top floor overlooking the city and an incredible sunset, gym and more. Surrounded by cafes, parks and everything you need to have the best experience in the city.

Top Guest favourite
The kitchen area features a black dining table with four chairs, complementing a modern microwave and refrigerator. Warm decorative elements, including wall art and a candle, add character to the space, which is equipped with essential appliances and a clean countertop.
Home in Panamá
4.94 out of 5 average rating, 399 reviews

Private Studio 10 Min from the Airport!

Entire apartment 10 minutes from the airport! The apartment is fully furnished including appliances and kitchen items, toiletries, dining room, work table and more. Just a few minutes walk from the SAN ANTONIO METRO Station, restaurants, shopping malls, laundries, supermarkets and pharmacies. We offer tours to San Blas to make the most of your trip. Our house is your house in Panama 🇵🇦

Top Guest favourite
A spacious living area is highlighted by large windows that offer views of urban high-rises and the distant ocean. A soft, rounded sectional sofa and a plush armchair provide comfort, while a dark area rug anchors the space beneath a sleek coffee table.
Apartment in Costa del Este
5 out of 5 average rating, 25 reviews

Elegant Apt in Costa del Este. Premium Amenities

Enjoy a luxurious stay in our modern design apartment located in the exclusive Costa del Este area. It has a room with a private bathroom, a cozy living room, and a fully-equipped kitchen. Building facilities include a state-of-the-art gym, swimming pool, and co-working space ideal for remote work. Perfect for extended stays, combining comfort and convenience in the heart of Panama.

Guest favourite
A cozy living area is illustrated with a modern television positioned on a wooden console. A dining table with a simple setting is visible, accompanied by dark-colored chairs. Light-colored tiles cover the floor, and a clock is mounted on the wall, providing a functional accent.
Apartment in Panamá
5 out of 5 average rating, 18 reviews

Cozy, downtown and accessible

Enjoy the simplicity of this cozy and centrally located accommodation. Fully equipped and close to everything (transportation, supermarket, parks, restaurants). Rest at ease and in peace, after a day full of activity in the wonderful city of Panama. It has TV, Internet, air conditioning, 1 luxury bathroom, hot water, top-notch white goods with internal laundry and parking.

Guest favourite
A small outdoor seating area is shown, featuring a blue two-seater sofa positioned against a green wall. Lush plants are visible nearby, and a covered terrace area offers shade. The flooring consists of tiled squares, creating a clean and inviting space.
Guest suite in Panamá
4.78 out of 5 average rating, 77 reviews

Nice and cozy studio apartment

Annex with private bathroom, kitchen and separate entrance, house in a very quiet residential development a few meters from the main road, close to supermarkets and shopping center. We have 1 dog and 1 turtle, the property has everything you need to have a pleasant stay, transportation service is offered if required.

Top Guest favourite
A stylish living area features a warm-toned sofa and modern circular coffee tables. Large windows with striped blinds allow natural light to enter, revealing a view of outdoor seating on a balcony. A round mirror and wooden sideboard add to the contemporary decor.
Apartment in Panamá
4.96 out of 5 average rating, 167 reviews

Superb Apartment In The Center Of Panama City

Luxurious, cozy, well-located 1-bed apartment in Panama City. Impeccably clean, stylishly furnished with a sofa bed. Experience the city's vibrant attractions, indulge in comfort, and make unforgettable memories. Your perfect getaway awaits! Book now for an exceptional stay.

Popular amenities for Santa Clara, Panama City holiday rentals

  1. Airbnb
  2. Panama
  3. San Miguelito
  4. Santa Clara