
House holiday rentals in Santa Cruz County
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Top-rated house rentals in Santa Cruz County
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Patagonia's Private Paradise
$130 PER NIGHT AS LOW AS $84.50 PER NIGHT FOR MONTH SUMMER IN PATAGONIA IS A WONDERFUL TIME SUMMER DISCOUNT READ OUR REVIEWS BEFORE YOU CHOOSE Patagonia is located high in the SKY ISLANDS of Southeast Arizona. The higher elevation and mountain forests make Patagonia much cooler than the Arizona cities at a lower elevation. Come to Patagonia and enjoy great discounts for longer-term stays at a time of year that many find nice and green. 20% OFF FOR 7 NIGHTS OR MORE 35% OFF FOR 28 DAYS OR MORE

Modern Elgin Home: Walk to Wineries + Pets Welcome
With its elegant design, secluded location, and 1-bedroom, 1-bath, ‘Starry Night Guest Retreat’ is the perfect cozy vacation rental! Start your days off by relaxing on the patio and admiring the views of the Mustang Mountains. When it’s time to explore, head to Deep Sky Winery for a glass of wine, try out some nearby birdwatching, or enjoy the farm animals grazing the meadow. Finish your stay with a visit to the old town of Tombstone and Kartchner Caverns State Park to see all that Elgin offers!

Sunny Arizona apartment for visiting or working
Discover the charm of a peaceful, centrally-located apartment perfect for two. This one-bedroom retreat is fully furnished, offering all the comforts of home with a fully equipped kitchen ready for your culinary adventures. Complete with fresh sheets and towels, this space is your ideal base for exploring the scenic Santa Cruz County and vibrant Nogales, Sonora. Whether you’re here for golfing, birdwatching, horseback riding, hiking, our cozy apartment puts all these activities within easy reach

Winemaker's Casita in the heart of Wine Country
The perfect casita for your wine tasting getaway! Our cozy space is full of local charm and minutes away from Elgin and Sonoita's many wineries. Centrally located near the Sonoita Crossroads, the Winemaker's Casita is walking distance from local restaurants, including Copper Brothel Brewery and Tia 'Nita's Cantina. Owned + operated by the proprietors of Rune Wines. Please note that the Winemaker's Casita is located next door to the Adobe House. There is plenty of room for privacy, or book both!

Private Getaway: Pandora Ranch House in Arivaca
Pandora is a private remote hacienda located on 20 acres in the high grasslands of the Sonoran Desert with 6 bedrooms, 6 bathrooms, a fully equipped kitchen, a dining room, living room. A well maintained yard with mature trees and charcoal BBQ grills invites to enjoy time outside. Minutes away from the quaint town of Arivaca, Buenos Aires Wildlife Refuge, Arivaca Lake and the Coronado National Forest Pandora offers easy access to hiking, boating,fishing, bird watching and off road exploration.

Javelina Corner
Our place is close to Patagonia Lake, 10 minute drive, Patton's hummingbird center, 2 minute drive or 8 minute walk. There is access to the Arizona trail at two locations within 10-20 minute drive and numerous other hikes! Tombstone, Bisbee, The Art haven of Tubac is close by and Nogales Mexico is 19 miles. You’ll love our place because of the neighborhood, the coziness, and the comfy beds. Our place is good for couples, solo adventurers, business travelers, families , and furry friends (pets).

Serenity, Starlink and waking up with bird songs
Wake up to nothing but bird sounds, enjoy morning coffee and the bright stars in dark nights on the covered patio. Contemporary furnished, spacious guest house with beautiful Mountain Views, in rural location, but close vicinity to the towns of Patagonia and Sonoita. Open kitchen - dining area floor plan. The house is set up with all amenities needed by seasonal visitors and remote working professionals. No pets. A small dog may be ok. 1 month or longer preferred. Shorter stays on request.

A Tubac Getaway
Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!

Cottage on Santa Rita | Sundrenched 2 bd/1 bth
Nestled against the hill, this private, sun-filled home is located in the heart of Patagonia, a few quick steps to local businesses. Expansive patios and a cactus garden provide a hidden oasis behind the cottage - an ideal base for exploring the region's wineries, historic towns, gravel cycling, and forests. The home is fully updated, with a generously equipped kitchen, large master bedroom, washer/dryer, flexible second sleeping space, and tasteful minimalist southwest decor.

Peaceful SW-style ranch home in wine country
Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona's beautiful wine country! Our home is 3,000 square feet and sits on 20 acres, and is even walking distance to one winery. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities (and a half bath), an amazing kitchen, dining, and living space, and high-speed Internet, our home is ideal for two or three couples or a family getaway.

Mesquite Haven
Fantastic home located in a peaceful and beautiful community surrounded by desert nature. This Santa Fe style residence invites you to relax and escape a busy lifestyle while still having access to modern amenities. Enjoy life outdoors in a basically traffic free private community rich with local flora and fauna. The location is great for morning or evening walks or runs, Tubac Resort wedding guests, visits to the village, hiking trips, etc.

Sky Island Retreat Sonoita, AZ.
Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.
Popular amenities for Santa Cruz County house rentals
House rentals with a pool

Gallo Libre Ranch House in Arivaca, AZ

Charming Tubac Villa within Tubac Golf Resort

Poolside Escape Near Patagonia

Casa de Anza

Stylish Townhome, 2BD, 2BA-Pool & Gym Access.

Cozy 2 bedroom townhouse, Tubac

Walk to Tubac village and birding/hiking trail!

Valle Verde Ranch House.
Weekly house rentals

HeART OF TUBAC

Saltwater House

Tubac private getaway!

Starbird Ranch - a piece a quiet solitude

Peaceful & Historic Home in Patagonia!

Sunset Views, EV Charger & Mountain Backdrop

The Somm's Aviary

the historic "Border View" home
Private house rentals

Cozy, Pet Friendly, Home in the town of Patagonia

Desert Oasis Retreat

Pets OK Charming Immaculate home EZ to I-19

Casa de la Paz

Quiet, airy home in Nogales, in the hills.

Cozy stay in wine country at Penelope's Place

Maria's Retreat - Walking distance to the Resort!

Pastoral Elgin Escape w/ Covered Patio & Grill!
Destinations to explore
- Rentals with a washing machine and dryer Santa Cruz County
- Rentals with a hot tub Santa Cruz County
- Rentals with a patio Santa Cruz County
- Rentals with pools Santa Cruz County
- Pet-friendly rentals Santa Cruz County
- Apartment rentals Santa Cruz County
- Rentals with a fire pit Santa Cruz County
- Rentals with outdoor seating Santa Cruz County
- Rentals with a fireplace Santa Cruz County
- House rentals Arizona
- House rentals United States
- Saguaro National Park
- University of Arizona
- Children's Museum Tucson
- Kartchner Caverns State Park
- Arizona-Sonora Desert Museum
- Tucson Botanical Gardens
- Reid Park Zoo
- Patagonia Lake State Park
- Titan Missile Museum
- Tumamoc Hill
- Mission San Xavier del Bac
- University of Arizona
- Sonoita Vineyards
- Kino Sports Complex
- Tucson Convention Center
- Gene C Reid Park
- Pima Air & Space Museum
- Tumacacori National Historical Park
- Trail Dust Town
- Rialto Theatre
- Mini Time Machine Museum of Miniatures
- Tucson Museum of Art




