
House holiday rentals in Santa Cruz County
Find and book unique houses on Airbnb
Top-rated house rentals in Santa Cruz County
Guests agree: These houses are highly rated for location, cleanliness and more.

Modern Elgin Home: Walk to Wineries + Pets Welcome
With its elegant design, secluded location, and 1-bedroom, 1-bath, ‘Starry Night Guest Retreat’ is the perfect cozy vacation rental! Start your days off by relaxing on the patio and admiring the views of the Mustang Mountains. When it’s time to explore, head to Deep Sky Winery for a glass of wine, try out some nearby birdwatching, or enjoy the farm animals grazing the meadow. Finish your stay with a visit to the old town of Tombstone and Kartchner Caverns State Park to see all that Elgin offers!
LocationFamilyHospitality

Private Getaway: Pandora Ranch House in Arivaca
Pandora is a private remote hacienda located on 20 acres in the high grasslands of the Sonoran Desert with 6 bedrooms, 6 bathrooms, a fully equipped kitchen, a dining room, living room. A well maintained yard with mature trees and charcoal BBQ grills invites to enjoy time outside. Minutes away from the quaint town of Arivaca, Buenos Aires Wildlife Refuge, Arivaca Lake and the Coronado National Forest Pandora offers easy access to hiking, boating,fishing, bird watching and off road exploration.
LocationValueLaundry

Javelina Corner
Our place is close to Patagonia Lake, 10 minute drive, Patton's hummingbird center, 2 minute drive or 8 minute walk. There is access to the Arizona trail at two locations within 10-20 minute drive and numerous other hikes! Tombstone, Bisbee, The Art haven of Tubac is close by and Nogales Mexico is 19 miles. You’ll love our place because of the neighborhood, the coziness, and the comfy beds. Our place is good for couples, solo adventurers, business travelers, families , and furry friends (pets).
ValueLocationAccuracy

McFitz Guest Ranch
McFitz Ranch House is fully remodeled and available. Its a 3000 sqft 4 bedroom 3 bathroom w/ two master suites, and game room on 5 acres of beautiful horse property. Close to many attractions such as several wineries, brewery, the Sonoita rodeo grounds, Parker Canyon and Patagonia Lake, La Cienega Preserve and more. This location is ideal for Wedding Parties, Wine vacations, Rodeo, Kentucky Derby Fans, bird watching the Santa Cruz County Fair, hunting seasons or family weekends to the lake
ValueLocationSleep quality

Peaceful SW-style ranch home in wine country
Welcome to our southwestern style ranch home in Sonoita/Elgin, Arizona wine country! Our home is 2,600 square feet and sits on 40 acres with unobstructed views of the beautiful Santa Rita Mountains. Our entire home is available for a wine country getaway. With three bedrooms, two full bathrooms with dual vanities, a half bath, an amazing kitchen, dining, two living spaces, and high-speed Internet, our home is ideal for two or three couples, or a family getaway (crib available for use).
ValueFamilyBiking

A Tubac Getaway
Amazing luxury vacation rental in beautiful, historic Tubac, Arizona. Located in The Sanctuary neighborhood, this home is within walking distance of either The Village of Tubac or the Tubac Golf Resort. Plenty of nearby activities including hiking, golf, birdwatching, or day trips to southern Arizona. Visit unique shops in The Village of Tubac or the Resort for furnishings, jewelry, or great food at a variety of restaurants. Come see everything that southern Arizona has to offer!
ValueLocationBreakfast

Cottage on Santa Rita | Sundrenched 2 bd/1 bth
Nestled against the hill, this private, sun-filled home is located in the heart of Patagonia, a few quick steps to local businesses. Expansive patios and a cactus garden provide a hidden oasis behind the cottage - an ideal base for exploring the region's wineries, historic towns, gravel cycling, and forests. The home is fully updated, with a generously equipped kitchen, large master bedroom, washer/dryer, flexible second sleeping space, and tasteful minimalist southwest decor.
ValueLocationHiking

Fully private casita in heart of town!
New local owners! Discounted summer rates! This popular 1-bedroom guest house in the heart of the village offers a comfortable and fully private space that is bright, thoughtfully decorated, and full of authentic Patagonia charm. Walkable to all of Patagonia's restaurants, shops, and birding and hiking trails, and only a 15 minute drive to Patagonia Lake, or a 20 minute drive to nearby wineries. This casita is the perfect home base for your Patagonia adventures!
LocationValueSleep quality

Peaceful Family Friendly + Fire Pit + Volleyball
Escape to this peaceful desert retreat nestled against the hills of Patagonia. With two bedrooms, a bonus office with daybed, and a spacious living area with pull out bed, the home comfortably hosts families or small groups looking to relax, explore, and enjoy the quiet beauty of Southern Arizona. Spend evenings under the twinkle lights around the fire pit, wake up to views of the hills, or enjoy a friendly match on the volleyball court.
FamilyLocationCleanliness

Sonoita Harvest Home - minutes from wineries
Relax and unwind in the heart of Arizona wine country. 4 sprawling acres, stunning views, just minutes from top-local wineries and restaurants. The house boasts 2100 square feet with 3 bedrooms, office, 2.5 bathrooms and sleeps 9-10. Large modern kitchen and open living spaces. Perfect for friends, families and couple getaways. Sip wine on the back patio, explore local wineries, and enjoy your own slice of countryside paradise!
FamilyLocationOutdoor spaces

Sky Island Retreat Sonoita, AZ.
Sky Island Retreat is a quiet and peaceful hilltop retreat in which you can relax and enjoy the natural beauty of this historic area. The casita is the original but updated ranch house built in the late 60’s. We have kept much of its original charm while upgrading to modern comfort and conveniences. We are located on a privately gated property just minutes from the heart of Sonoita and Southern AZ’s growing wine country.
ValueLocationBreakfast

Winemaker's Casita in the heart of Wine Country
The perfect casita for your wine tasting getaway! Our cozy space is full of local charm and minutes away from Elgin and Sonoita's many wineries. Centrally located near the Sonoita Crossroads, the Winemaker's Casita is walking distance from local restaurants, including Copper Brothel Brewery and Tia 'Nita's Cantina. Owned + operated by the proprietors of Rune Wines.
FamilyLocationGetting around
Popular amenities for Santa Cruz County house rentals
House rentals with a pool

Gallo Libre Ranch House in Arivaca, Arizona
LocationValueHeating

Beautifully Bewitching Mansion Indoor Pool

Poolside Escape Near Patagonia
LocationFamilyLayout

Casa de Anza
LocationNearbyIndoor spaces

Stylish Townhome, 2BD, 2BA-Pool & Gym Access.
LocationFamilyAccuracy

Cozy 2 bedroom townhouse, Tubac
LocationFamilyCleanliness

Walk to Tubac village and birding/hiking trail!
LocationValueWalkability

Valle Verde Ranch House.
LocationFamilyHiking
Weekly house rentals

Patagonia's Private Paradise
LocationValueAccuracy

Cozy stay in wine country at Penelope's Place
LocationFamilyKitchen

Vino y Vacas - Cozy Home - Heart of Wine Tasting
LocationLayoutView

Camp Cathy
FamilyLocationKitchen

Serenity, Starlink and waking up with bird songs
FamilyLocationOutdoor spaces

Mesquite Haven
FamilyLocationIndoor spaces

Tilted Horse Ranch in the heart of wine country
LocationFamilyBackyard

Casita de Tubac
LocationFamilyCheck-in
Private house rentals

Barrio Bungalow
FamilyLocationComfort

Tres Bellotas Ranch Guest House
FamilyLocationSleep quality

Mountain View Ranch Arizona
LocationFamilyPets

Casa Agave
LocationValueQuiet

Cosy House: Two bedroom - great WiFi and RO water
LocationFamilyNearby

YELLOW HOUSE NEAR THE BORDER
ValueLocationCleanliness

Pastoral Elgin Escape w/ Covered Patio & Grill!
FamilyLocationIndoor spaces

Historic Gomez House
LocationFamilySleep quality
Destinations to explore
- Rentals with a fireplace Santa Cruz County
- Rentals with a fire pit Santa Cruz County
- Rentals with pools Santa Cruz County
- Rentals with a hot tub Santa Cruz County
- Rentals with a washing machine and dryer Santa Cruz County
- Rentals with a patio Santa Cruz County
- Apartment rentals Santa Cruz County
- Pet-friendly rentals Santa Cruz County
- Rentals with outdoor seating Santa Cruz County
- House rentals Arizona
- House rentals United States
- University of Arizona
- University of Arizona
- Saguaro National Park
- Tumamoc Hill
- Kartchner Caverns State Park
- Patagonia Lake State Park
- Arizona-Sonora Desert Museum
- Tucson Botanical Gardens
- Sabino Canyon Recreation Area
- Tucson Convention Center
- Titan Missile Museum
- Reid Park Zoo
- Mission San Xavier del Bac
- Tucson Museum of Art
- Pima Air & Space Museum
- Rialto Theatre
- Mini Time Machine Museum of Miniatures
- Children's Museum Tucson
- Tumacacori National Historical Park
- Sonoita Vineyards
- Trail Dust Town
- Rune Wines
- Tubac Presidio State Historic Park
- Tucson Mountain Park





