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Holiday houses in Santa Cruz de la Sierra

Find and book unique accommodation on Airbnb

Quick stats about holiday rentals in Santa Cruz de la Sierra

  • Total holiday rentals

    Explore 4,380 holiday rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra holiday rentals start at $17 NZD per night before taxes and fees

  • Verified guest reviews

    Over 59,960 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,170 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 1,180 rentals that welcome pets

  • Holiday rentals with a pool

    2,980 properties feature pools

  • Rentals with dedicated workspaces

    2,510 properties have a dedicated workspace

  • Wi-Fi availability

    4,040 of Santa Cruz de la Sierra holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wi-Fi and Pool across Santa Cruz de la Sierra rentals

  • 4.7 Average rating

    Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests

Top-rated holiday rentals in Santa Cruz de la Sierra

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 7 reviews

Skyline Luxury • Rooftop, Piscina, Billar & Lounge

Designed for discerning guests seeking an experience superior to a 5-star hotel. Located in Equipetrol, the most exclusive and secure area of Santa Cruz, this elegant apartment on the second-to-last floor offers a double balcony with unique views! Premium amenities such as a sky pool, lounge, pool table, barbecue grills, fully equipped gym, and more! Surrounded by the best restaurants, bars, cafes, theaters, shops and business centers. Ideal for executive trips, luxury getaways or unforgettable stays.

LocationIndoor spacesHospitality

Superhost
A modern outdoor pathway is flanked by sleek buildings and lush greenery. Soft, natural light filters through the space, illuminating the smooth stone finish of the walkway. Curved steps lead up to elevated garden areas, creating a harmonious blend of nature and architecture.
Apartment in Santa Cruz de la Sierra
4.89 out of 5 average rating, 72 reviews

Luxury 18th-Floor Apt | City View, Pools & Netflix

Enjoy a comfortable and stylish stay in this modern 18th-floor apartment with panoramic city views in Santa Cruz. Ideal for families, business travelers, and groups, the apartment offers space, privacy, fast Wi-Fi, and resort-style amenities, all within a secure high-rise building. For security purposes, there is a Ring doorbell camera located outside the apartment entrance, facing the exterior hallway. There are no cameras inside the apartment. there is security on duty 24x7 4th bed inflatable

LocationFamilyNearby

Top Guest favourite
A modern living area features a comfortable sofa adorned with decorative pillows, alongside a sleek TV unit. Large windows offer panoramic city views, while two round mirrors enhance the brightness of the space. A small chair and indoor plant add a touch of decor.
Apartment in Santa Cruz de la Sierra
4.99 out of 5 average rating, 83 reviews

Equipetrol · 13th floor, great view and pool

✨ Enjoy a comfortable stay in Equipetrol, one of Santa Cruz’s most exclusive areas. The building offers shared areas: on the 4th floor you’ll find a spacious lounge with sofa, TV, air conditioning, and a pool table, along with a swimming pool and barbecue area; on the 17th floor you can enjoy the gym, another barbecue area, and city views. The apartment includes fast 293 Mbps Wi-Fi, an in-unit washer, 4K TV, air conditioning, and a fully equipped kitchen, ideal for business or leisure stays.

LocationValueIndoor spaces

Guest favourite
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 14 reviews

Sophisticated 2 Bedroom Absolute Luxury

Experience absolute luxury and superior sophistication. This exclusive 2-bedroom apartment redefines the concept of comfort in Equipetrol, the most prestigious area of SCZ. Each space has been carefully designed with elegant furnishings and a refined aesthetic that conveys distinction in every detail. Exclusive social areas: 🏊 Pool 💪 GYM 🎯 Playroom 🌇 Viewpoint with panoramic view Ideal for those looking for elegance and a superior experience in the best area of the city.

LocationComfortPool

Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 5 reviews

Luxurious | 23rd Floor View TOP Location WiFi

Enjoy a comfortable, safe, and conveniently located stay in this elegant 1-bedroom apartment in the exclusive Edificio Mare building in Santa Cruz de la Sierra. 🏢 Amenities • Pool • Gym. • 24/7 security • Steakhouse restaurants • Common areas 📍 Location Located in a convenient area, close to restaurants, supermarkets, and business centers. Things to ⚠️ know • No parties • Please do not smoke • Only registered guests 🚀 Bonus 👉 Ideal for long stays — discounts available

LocationIndoor spacesKitchen

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 81 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

FamilyLocationCheckout

Top Guest favourite
A modern living area is presented, featuring a comfortable gray sofa facing a large window with city views. A sleek, wall-mounted television is positioned above a stylish wooden console. Natural light fills the room, complemented by decorative plants and minimalist artwork.
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 55 reviews

Xquisite Suite - 1 Room Equipetrol North

Discover elegance in this cozy 1-bedroom apartment with dreamy views. Experience the luxury of extreme equipment with a 65" 4K HDR Smart TV in the living room and another 50" TV in the bedroom, powerful air conditioning equipment, a washing machine, and necessary appliances, an Ultra Comfort Queen bed, a changing table and a dresser, as well as home automation and Alexa to fulfill your orders. Experience the synthesis of modernity like never before, book NOW!

LocationKitchenBathroom

Superhost
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 5 reviews

POX | Green Tower - 21 | Luxury with Private Grill

Experience absolute luxury in this exclusive apartment on the 21st floor of the iconic Green Tower. Elegant design and panoramic city views. Enjoy a sophisticated living room, high-level dining room, fully equipped kitchen and a private balcony with its OWN BARBECUE, a unique luxury in the heights. The building offers a pool, sauna, social areas and 24/7 security, restaurants and bars. We'll make sure you have a memorable stay. Rest - Enjoy - Repeat Pox

LocationViewComfort

Top Guest favourite
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 81 reviews

Spacious 3-bedroom | heated pool | Macororo

Enjoy a comfortable and elegant stay in this spacious 3-bedroom apartment at Macororo 13/14, on Av. Los Cusis. Great for families, groups and business trips. • Heated pool and social areas • Free private parking • Fast Wi-Fi • Equipped kitchen • Washer & Dryer • Smart TV Within walking distance, you'll find a 24-hour supermarket, Starbucks, restaurants, a mall, and a gym in front of the building. A comfortable, safe space designed for an excellent stay.

FamilyLocationAir conditioning

Top Guest favourite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 31 reviews

Equipetrol, Fantastic 2 Bedroom Apartment

Enjoy luxury and comfort with your family in the best area of Santa Cruz, Equipetrol! Welcome to the exclusive ARA Tower, where modern design merges with functionality in this stylish 2 bedroom apartment fully equipped, for your comfort. We also offer: infinity pool, lounge, rooftop barbecue and 24/7 security. You'll be steps away from the best restaurants, cafes, and nightlife. Book now and have an unforgettable experience!

FamilyLocationTV

Guest favourite
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 30 reviews

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

LocationComfortIndoor spaces

Guest favourite
Apartment in Santa Cruz de la Sierra
4.94 out of 5 average rating, 17 reviews

The best view of Santa Cruz

From this apartment in the best area of Santa Cruz (Equipetrol Norte, in the business center) you will have the best apartment with a pleasant climate. It is located on the 16th floor, unsurpassed views and sunsets. The whole group will enjoy easy access to supermarkets, restaurants, pharmacies, banks, transportation, paddle courts, etc. The Ventura mall is steps away from the apartment.

LocationBarbecueHospitality

Popular amenities for Santa Cruz de la Sierra holiday rentals

Other great holiday rentals in Santa Cruz de la Sierra

Frequently Asked Questions

  • What are the best places to stay in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has stays in lively neighborhoods like Equipetrol, known for dining and nightlife, and around the city center near plazas and shops. Guests often appreciate areas with leafy streets, local cafes, and easy access to cultural sites.

  • What are the best things to do in Santa Cruz de la Sierra with kids?

    Families can explore city parks, interactive museums, and local zoos featuring native wildlife. Playgrounds and green spaces in residential neighborhoods add opportunities for outdoor fun.

  • What are some of the best things to do in Santa Cruz de la Sierra?

    Discover central plazas, explore Museo de Historia Natural Noel Kempff Mercado, and wander bustling traditional markets. The city also has botanical gardens, art spaces, and vibrant street life.

  • How is the weather in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra generally has warm, humid conditions year-round, with wetter spells in certain months and a tropical atmosphere. Lightweight clothing and sun protection are often suggested, especially for daytime outings.

  • What are the best places to visit in Santa Cruz de la Sierra?

    Explore Plaza 24 de Septiembre, admire local art at Museo de Arte Contemporáneo, and stroll the city’s botanical gardens. Markets and lively pedestrian zones add extra color to the experience.

  • What are some hiking trails in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has nature reserves and eco-parks where visitors can follow shaded trails amidst tropical plants and birds. Urban green spaces and parks also provide pathways for relaxed walks.

  • What are some family activities we can do in Santa Cruz de la Sierra?

    Families frequently explore city zoos, botanical gardens, interactive museums, and open-air playgrounds. Participating in local craft workshops or tasting fresh fruit at traditional markets brings a sense of discovery.

  • What are some of the best day trip ideas from Santa Cruz de la Sierra?

    Day trips often include exploring nature reserves, visiting Jesuit mission towns, or discovering small communities with locally rooted traditions. Eco-parks around the city provide hiking, birdwatching, and opportunities to connect with regional culture.

  • Are there any pet friendly accommodations available in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has pet-friendly vacation rentals in neighborhoods like Equipetrol, Urbarí, and around the city center. Many stays include access to green spaces and parks for walks with your pet.

  • What are some local tips for visiting Santa Cruz de la Sierra?

    Locals appreciate lightweight clothes for the heat, insect repellent, and comfortable shoes for exploring urban sights. Trying locally grown fruits at traditional markets is frequently suggested, and learning some Spanish phrases adds ease to your experience.

  • What is Santa Cruz de la Sierra known for?

    Santa Cruz de la Sierra is known for its lively main plaza, tropical botanical gardens, and dynamic blend of Indigenous and European traditions. The city’s vibrant markets, local cuisine, and arts scene are frequently highlighted.

  • What are the best hidden gems to explore in Santa Cruz de la Sierra?

    Around Santa Cruz de la Sierra, visitors often discover small artisan shops, tranquil eco-parks, and street murals tucked in residential neighborhoods. Community-run cafés and weekend craft markets add unique flavor.

  • What are the best foods to try in Santa Cruz de la Sierra?

    Local favorites include salteñas, sonso de yuca, and traditional dishes made from corn, plantain, and tropical fruits. Refreshing drinks such as mocochinchi and locally roasted coffee are often recommended.

  • What should I bring for a trip to Santa Cruz de la Sierra?

    Pack lightweight clothing, sun protection, insect repellent, and comfortable shoes for walking. Bringing a reusable water bottle and rain jacket can add convenience, especially if you plan outdoor excursions.

  • What is the nightlife in Santa Cruz de la Sierra like?

    Santa Cruz de la Sierra has lively nightlife, with bars and clubs frequently suggested around the Equipetrol neighborhood. In the city center, you can explore relaxed venues featuring live music, local cocktails, and outdoor patios.

  • What are the most popular events or festivals in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has celebrated cultural festivals, Carnaval, and regional fairs throughout the year. Music, dance, and food events are frequently suggested, especially around holidays and community celebrations.

  • Are there family friendly vacation rentals in Santa Cruz de la Sierra?

    Family-friendly vacation rentals can be found in Equipetrol, Urbarí, and the city center, many with spacious layouts and access to parks or play areas. Hosts often provide amenities for children to make visits comfortable.

  • When is the best time to visit Santa Cruz de la Sierra?

    Visitors often prefer the drier months for outdoor activities and exploring city sights, while some enjoy the lush greenery during wet seasons. Popular festivals and pleasant evenings draw many travelers throughout the year.