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Guesthouse holiday rentals in Santa Cruz Island

Find and book unique guesthouse rentals on Airbnb

Top-rated Guesthouses in Santa Cruz Island

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Private room in Puerto Ayora
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Suite con jacuzzi a pasos del malecón Puerto Ayora

🏝Suite con jacuzzi privado en el baño dentro de un moderno hotel con acceso a lobby, jardín, terraza ubicado a solo pasos del malecón de Santa Cruz cerca de principales sitios de visita. -👥Tarifa base para 2 personas. -➕Costo extra por huésped adicional. -🛀Jacuzzi en terraza disponible con costo adicional. -Desayuno, limpieza, lavandería con costo adicional. Comienza tu día disfrutando en la terraza al aire libre, zonas de descanso y espacios ideales para trabajar o comer con vista abierta.

The eco-chalet features a wooden staircase leading to a spacious front porch, framed by lush greenery. Large windows allow natural light to fill the interior, while the serene ocean views can be glimpsed in the background, enhancing the connection with nature.
Guesthouse in Puerto Ayora- playa de los alemanes
4.82 out of 5 average rating, 56 reviews

Galapagos - Santa Cruz Island - Janine's Chalet

Lose yourself inside the magic of nature offered by our mesmerizing Divines’ Bay Ocean-front Eco-chalets. For those looking to disconnect from busy city life, your waterfront chalet will give you the perfect backdrop of the majestic untouched wildlife of the Galapagos. While enjoying a cool drink, blue haroons and iguanas will become a part of your scenery to make your experience feel like a utopia. For those seeking adventure, swimming and snorkeling are available literally at your doorstep.

A spacious sleeping area contains a double bed dressed with light bedding. Two towels are neatly placed at the foot of the bed, accompanied by two rolled towels in vibrant colors. A small table and chair set is positioned by the large windows, which are covered with sheer curtains.
Private room in Puerto Ayora
4.5 out of 5 average rating, 58 reviews

Private suite with sea view

Charming apartment for two with a sea view on the main avenue, close to everything: pharmacies, banks, shops, restaurants, and bars. Enjoy comfort and seaside beauty during your stay, with everything just steps away. Encantador apartamento para dos personas con vista al mar en la avenida principal, cerca de todo: farmacias, bancos, tiendas, restaurantes y bares. Disfruta de la comodidad y la belleza marina durante tu estancia, con todo a pocos pasos de distancia.

Superhost
Private room in Puerto Ayora
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habitación matrimonial con vista al mar

Habitación cómoda y funcional con una recámara, ubicada dentro de un hotel en Galápagos, ideal para una persona o una pareja que busca descanso después de un día de playa y recorridos por la isla. El hotel cuenta con piscina, patio y mesas al aire libre para disfrutar de un ambiente tranquilo. Se encuentra a pocas cuadras del mar, lo que permite llegar caminando a la playa. Espacio limpio, bien cuidado y con excelente relación precio–calidad.

Guest favourite
An entrance is framed by lush greenery and flowering vines. The doorway leads into a space with light-colored walls and wooden elements, offering a view of the interior. Various plants surround the entrance, enhancing the natural ambiance.
Guesthouse in Puerto Ayora
4.88 out of 5 average rating, 72 reviews

Charles Darwin's Suite on the way to Tortuga Bay

¡Vive una experiencia auténtica en Galápagos! Alojamiento seguro, céntrico y eco-amigable, a solo 3 min de agencias, supermercados y la famosa Playa Tortuga Bay. ✨ Disfruta de: ✔ Cocina totalmente equipada ✔ WiFi rápido y estable ✔ Agua caliente con energía solar ✔ Espectacular jardín natural y zona de descanso 📌 Ubicación privilegiada + conexión con la naturaleza 💬 ¡Reserva ya! Escríbenos para más detalles. ¡Te esperamos!

Guest favourite
A private room features a wooden loft bed above a spacious bed, along with a small nightstand and a dresser. A step ladder provides access to the loft. Soft lighting illuminates the simple decor, creating a functional and restful environment.
Private room in Puerto Ayora
4.8 out of 5 average rating, 44 reviews

Rent - Room 2 - Twin & Bunk Bed - NO A/C

A simple place with the essential amenities for a quiet stay. Choose 1 or 2 beds Access the tourist spots quickly, just a 10-minute walk away: - Charles Darwin Station - Galapagos National Park - Beaches - Bars -Restaurants - Shops Just two blocks from the main avenue. CHECK-IN: 1:00 PM CHECK-OUT: 09:00 AM Contact us to receive information on arrival at the property. We always improve the room features.

Private room in Puerto Ayora

Family Room with Balcony

Discover Duncan Suites, the ideal place for your stay in Puerto Ayora. Just 5 blocks from Pelican Bay, enjoy a prime location near the esplanade, restaurants, and shops. Relax in spacious rooms with air conditioning, equipped kitchen and fast WiFi. Perfect for those seeking comfort, safety, and easy access to the wonders of the Galapagos. Your unforgettable experience starts here.

A narrow pathway is flanked by white-walled buildings featuring brown wooden doors and large windows. Vibrant pink flowers and lush green plants enhance the natural setting. The clear blue sky overhead complements the tranquil atmosphere of the courtyard.
Guesthouse in Puerto Ayora

Guesthouse

* Enjoy the simplicity of this quiet and central accommodation in Puerto Ayora - Isla Santa Cruz, Ecuador. * Located on the main street a few steps from the main dock * We have tourist agency so you can enjoy a fabulous experience in the Galapagos Islands * Find excellent restaurants with exquisito dishes in our surroundings * Come and enjoy a comfortable place in our stay

Top Guest favourite
A charming entrance features a wooden door framed by stone walls and surrounded by lush foliage. A winding staircase painted in calming blue leads up to the door, complemented by a decorative plant in a white pot at the base.
Guesthouse in Puerto Ayora
5 out of 5 average rating, 12 reviews

Cozy apartment

Forget your worries in this spacious and serene space, full of nature and amenities, in a quiet neighborhood of the Galapagos Islands, Santa Cruz.

A compact guest room features a spacious bed with a dark bedspread and a blue accent pillow. A wooden door leads to the room, while a closet with hangers provides storage space. A small desk and chair complete the setup, with overhead lighting illuminating the area.
Private room in Puerto Ayora
4.67 out of 5 average rating, 3 reviews

Accommodation Costa del Sol

Your family will be close to everything when you stay in this centrally located home.

A bright room features two beds and a comfortable chair, accompanied by a desk. Large windows with yellow curtains allow natural light to brighten the space. The orange floor complements the colorful plaid bed linens, creating a vibrant atmosphere.
Guesthouse in Santa Cruz

Valle del Amanecer Galapagos 2 Santa Cruz

We have banana fruit trees,oranges, seasonally an unforgettable place within nature.

A serene exterior view of a light-colored building is captured, featuring a curved wall adorned with lush tropical plants. Palm trees are visible nearby, and the setting includes a mix of modern and traditional architecture reflecting a peaceful neighborhood.
Guesthouse in Puerto Ayora

Casa Itabaca

Relájate con toda la familia en este alojamiento donde la tranquilidad se respira.

Popular amenities for Santa Cruz Island guesthouses