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House holiday rentals in Santiago Centro

Find and book unique houses on Airbnb

Quick stats about house rentals in Santiago Centro

  • Total holiday rentals

    Explore 260 holiday rentals in Santiago Centro

  • Verified guest reviews

    Over 7,290 verified reviews to help you choose

  • Family-friendly holiday rentals

    40 properties offer extra space and kid-friendly amenities

  • Pet-friendly accommodation

    Find 40 rentals that welcome pets

  • Holiday rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    120 properties have a dedicated workspace

  • Wi-Fi availability

    240 of Santiago Centro holiday rentals include Wi-Fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santiago Centro rentals

  • 4.8 Average rating

    Santiago Centro stays are highly rated by guests—averaging 4.8 out of 5!

  • Nearby attractions

    Santiago Centro's top spots, include Plaza de Armas of Santiago, Patio Bellavista, and Parque Forestal

Top-rated house rentals in Santiago Centro

Guests agree: These houses are highly rated for location, cleanliness and more.

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Top Guest favourite
Home in La Florida
4.94 out of 5 average rating, 167 reviews

House for 5 people• 2 bathrooms•Large garden•A/C•2 parking spaces

Casa para 5 personas en 2 dormitorios + living: 1 cama matrimonial, 3 individuales. Casa de 2 pisos cómoda y funcional, full equipada para grupos grandes. El gran protagonista es el jardín privado de 90m²: seguro para niños, perfecto para asados y con vista a la Cordillera. Incluye AC frío/calor y 2 estacionamientos dentro. esta prohibido fumar dentro del alojamiento, multa de 100 dólares por aire acondicionado, Ubicada en La Florida con bus a 30m. Cerca de Estadio Bicentenario, oulet Florida.

ValueFamilySleep quality

Top Guest favourite
Home in Providencia
5 out of 5 average rating, 50 reviews

Casa Caupolicán, Barrio Italia

Beautifully restored 1.000 ft2 house from 1936 with private garden of 900 ft2 with two terraces, lovely art and antique collection. The house is located in a quiet residential area, but a few blocks away from the well-known neighborhood of Barrio Italia, a vibrant commercial area, full of restaurants, fashion stores and antique shops. 10 minutes walking distance from the subway (Santa Isabel, Line 5), 2 minutes away from the nearest bus station, and 25 min cab ride from the airport.

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Guest favourite
Home in La Florida
4.92 out of 5 average rating, 222 reviews

Spacious 5-bedroom house • 12 beds • 14 people

Espectacular casa de 2 pisos en condominio con estacionamiento para 3 vehículos, quincho y piscina privados. 1 piso: - Dormitorio con cama King y baño privado con ducha - Dormitorio con litera - Cocina - Living y comedor 2 piso: - Dormitorio con cama de 2 plazas y cama individual - Dormitorio con litera nido y 1 cama individual - Dormitorio con cama nido y cama individual - Baño con ducha Patio con quincho, piscina y baño exterior Casa totalmente equipada con sabanas y toallas

ValueLocationBarbecue

Top Guest favourite
A dining table is set with plates and glassware, featuring a floral centerpiece of yellow calla lilies. The warm wood finish of the table contrasts with the light walls, while natural light filters in through a nearby window, enhancing the inviting ambiance of the space.
Home in Providencia
4.92 out of 5 average rating, 179 reviews

House Boutique, Pablo Neruda, Providencia 1 Neighborhood

Beautiful house located in the heart of the Providencia commune, a private residential area, with 24/7 private security. The house is located in front of the museum of the great Chilean poet Pablo Neruda, who in 1953 began building a house in Santiago for Matilde Urrutia, his then secret love. In her honor he named it “La Chascona”, which was the nickname he gave her because of her abundant red hair. House Boutique is located right in front of La Chascona on Chucre Manzur Street.

FamilyLocationComfort

Guest favourite
A modern living area features a blue couch and an armchair, complemented by decorative throw pillows. Two small coffee tables sit in front, while a wooden cabinet and wall-mounted shelves with plants and art pieces enhance the ambiance. Natural light filters through sheer blinds.
Home in Las Condes
4.82 out of 5 average rating, 169 reviews

Mahia House, Las Condes

Mahia House offers accommodation with free WiFi in Santiago near supermarkets and shops, steps from the Los Dominicos Mall, Parks, special to enjoy as a family. A 10-minute walk to the Los Dominicos metro station and the famous Pueblito Los Dominicos. The location is fantastic, Las Condes is a safe and wooded neighborhood. My family and I live in the "upstairs house" and we will always be attentive to what you need to make your stay literally at home and local. Welcome!!!

FamilyValueSkiing

Top Guest favourite
Home in La Florida
4.98 out of 5 average rating, 111 reviews

Large house located in the foothills of the Andes

Enjoy this Mediterranean-style home nestled in the Andes Mountains. This 200 m² property sits on a large lot with sweeping panoramic views of Santiago. With nearby parks and playgrounds, and on-site parking, it's ideal for families with children and pets. It's conveniently located near Starbucks, Shopping Malls, the Bahá'í Temple, and Panul Park, perfect for enjoying nature. Enjoy barbecues in the covered outdoor kitchen with family and friends. Don't miss out!

ValueLocationCleanliness

Superhost
A living room area features a high ceiling with exposed wooden beams. A spacious couch and armchairs are arranged around a coffee table, while natural light filters in through large windows. A dining area with modern chairs is visible in the background.
Home in Lo Barnechea
4.81 out of 5 average rating, 149 reviews

Spacious Remodeled House two floors + garden grill

Hola soy Joaquin Arriendo mi casa remodelada. Muy bien cuidada por mi señora decoradora de interiores Casa: 160mts Terreno: 300mts NO SE ADMITEN FIESTAS NO AUTORIZADAS, ESTAN PENALIZADAS CON UNA MULTA DE 1.000USD ATRAVES DE AIRBNB COVER (maximo 10 personas simultaneamente en la casa. Para mas se requiere autorización) El alojamiento esta equipado para que duerman 7 personas en camas. El huesped 8, 9 y 10 deben acomodarlo los huespedes a su conveniencia.

LocationValueCondition

Top Guest favourite
Home in La Reina
4.96 out of 5 average rating, 108 reviews

Independent House/Annex with Private Patio

A peaceful and completely private place in Santiago. Enjoy Santiago from a comfortable and quiet independent apartment, ideal for relaxing after exploring the city. Located in a safe residential neighborhood, with a private patio and excellent access to the Plaza Egaña and Simón Bolívar metro stations, and a shopping mall with essential services. Perfect for small families, couples, or business travelers seeking tranquility without being far from everything.

FamilyValueParking

Guest favourite
A private terrace features two lounge chairs facing a glimmering pool, designed for relaxation. Lush greenery surrounds the area, creating a tranquil setting. Large glass doors reflect the sunlight and offer glimpses of the interior space. The ambiance highlights a seamless connection with nature.
Home in Las Condes
4.91 out of 5 average rating, 35 reviews

Casa El Golf · Exclusive and Safe Neighborhood

Enjoy a luxury experience in Las Condes. This exclusive residence offers spacious heated spaces, an equipped kitchen, high-standard bedrooms (including a suite with a king-size bed), and a private pool, perfect for relaxing in total privacy. Located in a safe area next to the U.S. Embassy, with easy access to restaurants, boutiques, shopping malls, and cultural attractions. Ideal for business or pleasure trips. An exceptional stay awaits you.

LocationFamilyCheck-in

Top Guest favourite
Home in Peñalolén
4.97 out of 5 average rating, 71 reviews

Private Tiny House in Santiago whit HotTube

Escape to an urban oasis in our cozy 18 m² Tiny House. Unwind and recharge with everything you need for a relaxing stay. Enjoy a private swimming pool, fully equipped kitchen, 2 bathrooms, covered parking, indoor and outdoor dining areas, and a comfortable queen-size bed. Experience the charm of Tiny House living while staying in the city. Perfect for couples seeking a peaceful and unique getaway. Hot tub available for an additional fee

LocationComfortHot tub

Top Guest favourite
Home in Vitacura
5 out of 5 average rating, 26 reviews

Guest house with a private garden.

The guest house is on a very quiet street in Vitacura, steps away from Bicentenario Park, Casa Costanera, award-winning restaurants, and art galleries. With a private garden and furnished terrace. Ideal for one or two couples or a family with children (max 4 people). Newly remodeled with a full kitchen. The guest house is private but attached to the main house so no parties or events are allowed. It has a piano for music lovers.

FamilyLocationHospitality

Guest favourite
A cozy sleeping area features a spacious bed adorned with decorative pillows. A large window provides views of the surrounding greenery, while a small bedside table holds a reading lamp and a vase with fresh flowers.
Home in Lo Barnechea
5 out of 5 average rating, 19 reviews

Exclusive hideaway in La Dehesa

Escape to this unique house in La Dehesa, located on a large plot of land surrounded by nature. Enjoy total privacy with all the amenities you need, spacious spaces and a quiet environment, ideal for disconnecting and relaxing. It also has great connectivity with the Costanera Norte and important shopping centers in the city. The house is fully equipped, has a Smart TV, air conditioning, parking, a gas BBQ and a nice garden.

LocationFamilyCondition

Popular amenities for Santiago Centro house rentals

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Destinations to explore