
Mansion holiday rentals in Santo Domingo
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Santo Domingo
Guests agree: These mansions are highly rated for location, cleanliness and more.

Casa Pantheon Luxury Colonial House
Step back in time in this home first built in 1500 and located in the full heart of Colonial Zone in Santo Domingo, Pedestrian area. The estate, completely renovated in the year 2019, weaves modern luxury into spectacular Spanish colonial architectural elements, showcasing exposed brick, beamed ceiling, archways, courtyard patios, and all other facilities: steam bath, Wi-Fi, 2 smart tv, full Air Cond Totally Private Access to Pool, Jacuzzi and all the spaces of the House. Maid Service INCLUDED
FamilyLocationCheckout

Beautiful Modern Penthouse close to Zona Colonial.
Ideal for groups, Perfectly located in prestigious Gascue next to Palacio Bellas Artes, close to everything. Large 2 floor Penthouse (both floors elevator access). 4 Bedrooms with AC/4.5 Baths, Ocean/City views, 2 floors, 2 rooftop terraces, 2 parking spaces. Walk to El Malecon, Restaurants, Banks, Market and a short 8 minute drive to Zona Colonial, City Center, Plastic Surgery Clinics and attractions. Dedicated work space with internet, 5 smart TVs and much more. Smart lock for easy check-in.
LocationFamilyWalkability

Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.
FamilyValueAmenities

VillaRosario-Resort-Poolhothub NearAirport & Beach
¡Escápate a nuestra lujosa villa tropical en Santo Domingo Este carretera Samana , República Dominicana! Ideal para familias, amigos y reuniones, este amplio refugio cuenta con 6 habitaciones, 12 camas y 3 piso, acogedora iluminación ambiental. Sal al exterior y sumérgete en un paraíso exuberante, disfruta de delicias orgánicas del jardín de frutas y relájate junto a la piscina privada con una relajante cascada y jacuzzi. Los entusiastas del deporte adorarán la cancha de baloncesto privada.
LocationFamilyView

Eclectic,Spacious,4BR Penthouse
Air conditioner is fixed in the living room! Completely renovated Colonial Apartment-Penthouse on Famous El Conde St . in the heart of Zona Colonial. M-lily Mattresses ,Luxury Bedding Lacoste , CK ,RL Brand new Fully equipped Chef Kitchen with top brands cooking tools Self check-in Laundry&market service available Gym next door , day pass $2 Safest location Politur HQ across street Shampoo &bodywash Bright,Airy,Fresh Latest tech lighting crib XLL Balcony 24/7 electric kit
FamilyValueView

Casa del Orfebre, circa 1525
Welcome to Casa del Orfebre, a jewel from the past, where history comes alive and the charm of the 16th century is breathed in every corner. This antique house, meticulously restored and consolidated, is located in the heart of the Colonial City and is one of the historical buildings certified by the colonial heritage of Santo Domingo, declared a World Heritage Site by UNESCO. 3 rooms have queen beds and 1 room with 2 double beds. So for 10 guests it is a perfect accommodation.
ValueFamilyBarbecue

Luxury Rooftop Penthouse|Chef Experience|Sleeps 10
Indulge in a luxury rooftop lifestyle with this stunning penthouse, complete with a private jacuzzi, lounge, and panoramic city views. Elevate your stay with a private chef experience available upon request, creating unforgettable dining moments in total privacy. Ideal for families and groups, this expansive residence comfortably accommodates up to 10 guests while maintaining privacy, elegance, and high standards Note: Private chef service must be arranged in advance.
ValueLocationCheckout

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.
FamilyLocationAir conditioning

Paradise Luxury Penthouse With Private Jacuzzi
Apartamento cómodo y limpio en una area segura. Ubicado en la avenida España. A solo 20 minutos del aeropuerto, 25 minutos de la playa boca chica y 15 mins de la zona colonial. Cuenta con multiple opciones de restaurantes, bars, mixers, supermercado, farmacias, bodegas o colmados y mas a solo minutos. Aire acondicionado en cada dormitorio siempre que haya energía eléctrica, de no haber contamos con abanicos movidos por un inversor.
ValueFamilyAccuracy

Spacious house, gated community of Alma Rosa I
Esta casa se encuentra en un residencial cerrado y muy seguro. Està centralmente ubicada; a sólo 20 minutos del aeropuerto de Las Americas y a pocos minutos de los lugares más icónicos del gran Santo Domingo. También puede trasladarse caminando a los restaurantes, supermercado y centros comerciales del area. Ofrecemos check- in temprano y check-out tarde, segun las reservaciones que tengamos pendientes.
LocationValueOutdoor spaces

Penthouse 5BR | Billar | City View | Terrace Top
Experience a modern 3-level penthouse in the heart of Evaristo Morales. With 5 bedrooms, spacious living areas, a private terrace, and elegant design, it’s ideal for families and groups. Steps from Gold’s Gym, Smart Fit, supermarkets, restaurants, and banks, and minutes from BlueMall, Acropolis, and Ágora Mall. Enjoy comfort, style, and the best location in Santo Domingo.
ValueLocationHospitality

Villa Francisco RD, (15min Airport) Chef Included.
Do you want to disconnect and enjoy nature? This modern, welcoming apartment is ideal for a weekend with the whole family and will make you feel at home. Enjoy one of the best outdoor spaces by the pool, where you can prepare a delicious barbecue while relaxing and soaking up the sun. 15 minutes from Aeropuerto de las Americas (airport) and 12 minutes from downtown.
FamilyLocationWi-Fi
Popular amenities for Santo Domingo mansion rentals
Luxury mansion rentals

8-Bedroom Penthouse: Jacuzzi, Pool Table, Terrace
LocationFamilyAccuracy

Villa Sabrina
LocationFamilyOutdoor spaces

Domus Santa Barbara Pool House Sleeps 12
LocationFamilyIndoor spaces

FIXIE Lofts: Elegant Colonial Villa with Pool
LocationFamilyAmenities

✔️ 20-PAX VILLA | POOL | 8-BEDROOM | ZONA COLONIAL
ValueLocationAmenities

La Casona del Higuero, a paradise in Santo Domingo,
ValueFamilySleep quality

® {Acqualina's ~ Views} @ DowntownSD + 4BR Penthouse + Pool
ValueLocationDecor

The Dream House
FamilyValueBarbecue
Pet-friendly mansion rentals

villa yaya
LocationFamilyGetting around

Elegante y amplia casa zona céntrica Santo Domingo

Bonita villa RD
ValueFamilyAir conditioning

6 Bedrooms Vacation Home & Pool (Apartment G-102)
LocationFamilyComfort

Spacious 4BR pool house with private parking
ValueLocationAccess

White House Villa Santo Domingo
FamilyLocationIndoor spaces

Penthouse with Private Terrace Pool overlooking the Sea
FamilyLocationAmenities

Private Pool, Fast Wi-Fi, A/C, Near Zona Colonial
ValueLocationKitchen
Mansion rentals with a pool

Beverly Hills Residencíal
ValueLocationOutdoor spaces

House for groups with a pool SDE
FamilyValueGetting around

Experience Ultimate Comfort | 4BR Home
FamilyLocationAccuracy

Beautiful house with pool near Los 3 Ojos Park
FamilyHospitalityBreakfast

Comfortable and complete apartment
FamilyLocationHospitality

Spacious Villa for large groups with Private Pool
FamilyValueWi-Fi

Luxurious house with pool
LocationFamilyCondition

Luxe 4 Bedrooms, Pool, King Beds
FamilyValueLaundry
Destinations to explore
- San Juan Holiday rentals
- Higüey Holiday rentals
- Santiago De Los Caballeros Holiday rentals
- Punta Cana Holiday rentals
- Santo Domingo Este Holiday rentals
- Las Terrenas Holiday rentals
- Puerto Plata Holiday rentals
- Jarabacoa Holiday rentals
- Fajardo Holiday rentals
- La Romana Holiday rentals
- Ponce Holiday rentals
- Luquillo Holiday rentals
- Rentals with lake access Santo Domingo
- Waterfront rentals Santo Domingo
- Aparthotel rentals Santo Domingo
- Private suite rentals Santo Domingo
- Pet-friendly rentals Santo Domingo
- Bed and breakfasts Santo Domingo
- Family-friendly rentals Santo Domingo
- Loft rentals Santo Domingo
- Rentals with breakfast Santo Domingo
- Hostel rentals Santo Domingo
- Beachfront rentals Santo Domingo
- Holiday home rentals Santo Domingo
- Rentals with a hot tub Santo Domingo
- Guesthouse rentals Santo Domingo
- Rentals with pools Santo Domingo
- Boutique hotels Santo Domingo
- Condo rentals Santo Domingo
- Rentals with a sauna Santo Domingo
- Hotel rooms Santo Domingo
- House rentals Santo Domingo
- Apartment rentals Santo Domingo
- Serviced apartment rentals Santo Domingo
- Ski-in/ski-out rentals Santo Domingo
- Rentals with beach access Santo Domingo
- Villa rentals Santo Domingo
- Rentals with an accessible height bed Santo Domingo
- Mansion rentals Dominican Republic
- Playa Nueva Romana
- Ciudad Juan Bosch
- Malecón
- Metro Country Club
- Playa Guayacanes
- Blue Mall
- Playa Hemingway
- Downtown Center
- Megacentro
- Agora Mall
- Zona Colonial
- Teatro Nacional Eduardo Brito
- Bella Vista Mall
- Galería 360
- Dr. Rafael Ma. Moscoso National Botanical Garden
- Parque Iberoamerica
- Cathedral of Santa María la Menor
- Columbus Park
- The 3 Eyes National Park
- Columbus Lighthouse
- Casa De Teatro
- Playa Caribe
- Kahkow Experience
- Independence Park
- Things to do Santo Domingo
- Nature and outdoors Santo Domingo
- Outdoors Santo Domingo
- Workouts Santo Domingo
- Food and drink Santo Domingo
- Cultural tours Santo Domingo
- Art and culture Santo Domingo
- Things to do Distrito Nacional
- Nature and outdoors Distrito Nacional
- Outdoors Distrito Nacional
- Cultural tours Distrito Nacional
- Workouts Distrito Nacional
- Food and drink Distrito Nacional
- Art and culture Distrito Nacional
- Things to do Dominican Republic
- Performances Dominican Republic
- Tours Dominican Republic
- Outdoors Dominican Republic
- Landmarks Dominican Republic
- Sightseeing Dominican Republic
- Workouts Dominican Republic
- Food and drink Dominican Republic
- Nature and outdoors Dominican Republic
- Cooking Dominican Republic
- Water sports Dominican Republic
- Tastings Dominican Republic
- Art workshops Dominican Republic
- Cultural tours Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Food tours Dominican Republic
- Art and culture Dominican Republic







