
Holiday houses in Santo Domingo
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Top-rated holiday rentals in Santo Domingo
Guests agree: these stays are highly rated for location, cleanliness and more.

Playa Laska – Oceanfront Escape with Infinity Pool
Welcome to Playa Laska, a luxury beachfront villa where tropical elegance meets modern comfort. With three beautifully designed bedrooms, a private infinity pool, and open-air decks surrounded by lush greenery, every corner invites you to unwind, connect, and savor the ocean breeze. Start your mornings with the sound of waves, relax by the pool or stroll along the shore, and let evenings unfold with dining under the stars. Every corner is thoughtfully crafted for a seamless and relaxing stay.
LocationFamilyView
5.0 out of 5 average rating, 13 reviews
Disfruta una Casa de Playa frente al mar, patio
Playa El Jobo, es un lugar mágico, especial para conectar con la naturaleza y descansar. Está frente al mar a 9 metros de altura, lo que permite recibir el fresco de la brisa marina. La finca tiene una casa de madera de PB y un alto. En PB encuentras la cocina, dos baños completos, dos duchas al aire libre y un espacio techado para estar con hamacas. En planta alta hay un gran balcón con hamacas, dos recamaras, un área de estar y dos baños. Hay buena iluminación, ventilación natural y a/c
FamilyLocationWi-Fi
4.77 out of 5 average rating, 130 reviews
Drones Pedasi Ranch - Beach Pool Folk Fest Fishing
FAMILIES will Relax at this peaceful on the beach complete Ranch-House. Restaurant near by or drive (5) min to Pedasi's Town Center or Children can be kept close, a bunk-bed is near the King Size bed, with TV and Disney channel in the spacious Main room . Two other bedrooms with two Double-Bed each. All rooms with Bathroom and closet. Separate Kitchen & Dinning room with a relaxing view of the Ocean and wilderness. Ask us about tours to Isla Iguana, fishing trip or Horse back-riding.
FamilyLocationCheckout
4.81 out of 5 average rating, 43 reviews
2nd floor Beach Apartment with Amazing Views!
Enjoy beach life all year round in Panama at Uverito Beach! Go to the beach anytime you want, it is literally at your footsteps or relax in a hammock. This 2 bedroom 1 bath 2nd floor unit has all the amenities that will make your stay comfortable. Long-term rental is also available plus electricity (except long-term rental of 28 days or more you pay), you get a smart TV, unlimited bandwidth Wi-Fi internet, hot water shower, and brand new kitchen appliances to include a dishwasher.
ValueFamilyNearby
4.62 out of 5 average rating, 84 reviews
Loft Conivan-Las Tablas
Disfruta de Las Tablas como en casa en este amplio y cómodo apartamento completo. Ubicado en un primer piso. Equipado para estancias cortas o largas, con cocina completa, sala acogedora, aire acondicionado y WiFi, ideal para todo tipo de viajeros. A pocos minutos encontrarás playas, restaurantes, supermercados y los principales puntos turísticos del pueblo. Ya sea que vengas por celebración, descanso, o paseo este alojamiento es el punto de partida perfecto para disfrutar Las Tablas.
LocationFamilyParking
4.94 out of 5 average rating, 18 reviews
Casa de Campo con Piscina en La Enea de Guararé
Lejos de la urbe capitalina, ven a disfrutar del folklore panameño en un espacio rústico pero acogedor viviendo una experiencia autóctona. Relájate en la piscina ó descansa en una hamaca, respira aire puro, cerca del mar, rodeado de jardines amplios y naturales para un buen paseo. Cerca del Puerto de Guararé donde disfrutarás de los mejores mariscos y bebidas ó disfruta el corazón del mejor evento del folklore resaltando las tradiciones y las mejores polleras panameñas.
FamilyLocationNearby
4.96 out of 5 average rating, 57 reviews
Private Beach Studio · Sunset & Nature Views
Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city
LocationAir conditioningNearby
4.95 out of 5 average rating, 57 reviews
Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.
ValueFamilyCheckout
4.98 out of 5 average rating, 84 reviews
Descanso Junto al Mar
Vive el mar de cerca en este apartamento independiente y privado. Relájate en tu terraza con hamaca, disfruta las brisas y camina solo cruzando la calle para llegar a la playa. Cocina tu propia comida o prueba los restaurantes cercanos. Todo lo que necesitas está a mano: transporte diario, supermercados y hospitales a 15 min. Conoce Santo Domingo, pueblo artesanal de la Pollera panameña, a solo 15 min. Descanso, mar y cultura en un mismo lugar.
LocationNearbyWi-Fi
5.0 out of 5 average rating, 9 reviews
Casa Pelicano - Tropical house w pool and seaview
Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.
LocationFamilyComfort
4.9 out of 5 average rating, 84 reviews
Una Buena Caminata-Pedasi
Una Buena Caminata is a quiet, spacious villa designed as a retreat base—where days unfold slowly and logistics are handled with care. Set between the town center and Playa El Arenal, the gateway to Isla Iguana, the property offers both connection and seclusion in equal measure. This is not a resort and not a hands-off rental. It is an intentionally curated space for guests who value privacy, ease, and thoughtful living. .
FamilyLocationComfort
4.9 out of 5 average rating, 20 reviews
Luxury villa with ocean view near Playa Venao
Villa Bambú is a private tropical retreat where modern design meets nature. Wake up to open ocean views, unwind by your private pool, and enjoy the peace of an exclusive setting just minutes from Playa Venao. Perfect for disconnecting, recharging, or working remotely in a calm and inspiring environment.
LocationFamilyComfort
5.0 out of 5 average rating, 14 reviewsPopular amenities for Santo Domingo holiday rentals
Other great holiday rentals in Santo Domingo

Casa de campo acogedora en Las Tablas
ValueLocationHospitality
4.87 out of 5 average rating, 23 reviews
House for groups near Las Tablas and beaches
PetsSleep qualityBathroom
4.8 out of 5 average rating, 5 reviews
3- Las Tablas Comfy and Spacious Private Room
FamilyLocationOutdoor spaces
5.0 out of 5 average rating, 10 reviews
Casa entera -7 min de Las Tablas
Wi-FiAccuracyHospitality
5.0 out of 5 average rating, 4 reviews
Apartamento con estacionamiento
FamilyCleanlinessHospitality
5.0 out of 5 average rating, 3 reviews
2BR/2BA Pedasi Condo | Close to Beach & Town
FamilyLocationView
4.9 out of 5 average rating, 10 reviews
Cozy country home
ValueLocationLong stay
4.75 out of 5 average rating, 85 reviews
Casa familiar para 8 | 3 habitaciones con a/c
ValueFamilyIndoor spaces
4.91 out of 5 average rating, 11 reviewsDestinations to explore
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