Holiday houses in Santo Domingo

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santo Domingo

Guests agree: these stays are highly rated for location, cleanliness and more.

1 of 1 pages1 / 1

Guest favourite

Villa in Playa Venao

5 out of 5 average rating, 11 reviews

Playa Laska – Oceanfront Escape with Infinity Pool

Welcome to Playa Laska, a luxury beachfront villa where tropical elegance meets modern comfort. With three beautifully designed bedrooms, a private infinity pool, and open-air decks surrounded by lush greenery, every corner invites you to unwind, connect, and savor the ocean breeze. Start your mornings with the sound of waves, relax by the pool or stroll along the shore, and let evenings unfold with dining under the stars. Every corner is thoughtfully crafted for a seamless and relaxing stay.

LocationFamilyGetting around

Guest favourite

A private pool is framed by a stone patio, surrounded by lush greenery and tropical plants. A shaded area features outdoor seating and a grill, while the enclosed space provides a sense of tranquility. The home is visible in the background, set against a clear blue sky.

Home in Pedasí

4.92 out of 5 average rating, 199 reviews

3 min to Pedasi, 5 min to the Beach, Private Pool!

Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

ValueFamilyAmenities

Guest favourite

Cottage in Pedasí

4.83 out of 5 average rating, 41 reviews

Drones Pedasi Ranch - Beach Pool Folk Fest Fishing

FAMILIES will Relax at this peaceful on the beach complete Ranch-House. Restaurant near by or drive (5) min to Pedasi's Town Center or Children can be kept close, a bunk-bed is near the King Size bed, with TV and Disney channel in the spacious Main room . Two other bedrooms with two Double-Bed each. All rooms with Bathroom and closet. Separate Kitchen & Dinning room with a relaxing view of the Ocean and wilderness. Ask us about tours to Isla Iguana, fishing trip or Horse back-riding.

FamilyLocationPool

Guest favourite

Apartment in Las Tablas

4.94 out of 5 average rating, 17 reviews

Loft Conivan-Las Tablas

Disfruta de Las Tablas como en casa en este amplio y cómodo apartamento completo. Ubicado en un primer piso. Equipado para estancias cortas o largas, con cocina completa, sala acogedora, aire acondicionado y WiFi, ideal para todo tipo de viajeros. A pocos minutos encontrarás playas, restaurantes, supermercados y los principales puntos turísticos del pueblo. Ya sea que vengas por celebración, descanso, o paseo este alojamiento es el punto de partida perfecto para disfrutar Las Tablas.

LocationFamilyWalkability

Superhost

A sunset over the ocean is captured, reflecting golden hues across the water. The shoreline is visible with gentle waves lapping at the beach. A portion of the house is seen in the foreground, surrounded by greenery and colorful flowers.

Apartment in Las Tablas

4.61 out of 5 average rating, 82 reviews

2nd floor Beach Apartment with Amazing Views!

Enjoy beach life all year round in Panama at Uverito Beach! Go to the beach anytime you want, it is literally at your footsteps or relax in a hammock. This 2 bedroom 1 bath 2nd floor unit has all the amenities that will make your stay comfortable. Long-term rental is also available plus electricity (except long-term rental of 28 days or more you pay), you get a smart TV, unlimited bandwidth Wi-Fi internet, hot water shower, and brand new kitchen appliances to include a dishwasher.

LocationValueTV

Guest favourite

A bright bedroom is displayed, featuring a spacious bed covered with a textured white blanket. A television is mounted on the wall opposite the bed. Natural light floods through large windows, accompanied by sheer curtains. A cozy orange chair and potted plant add a touch of warmth.

Tiny home in Playa El Jobo

4.94 out of 5 average rating, 50 reviews

Private Beach Studio · Sunset & Nature Views

Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city

LocationSleep qualityNearby

Guest favourite

A modern tropical home is set amid lush greenery, featuring an expansive deck that connects to a serene pool. Large glass doors provide a view of the inviting interior and allow natural light to fill the space. Mountains and trees frame the backdrop.

Home in Playa Venao

4.98 out of 5 average rating, 82 reviews

Casa Samambaia - sea view tropical paradise w pool

With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

ValueLocationWalkability

Guest favourite

Home in Playa Venao

4.9 out of 5 average rating, 81 reviews

Casa Pelicano - Tropical house w pool and seaview

Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

LocationValueQuiet

Guest favourite

Apartment in La Pasera

4.86 out of 5 average rating, 7 reviews

Cómodo apartamento en Las Tablas, zona tranquila

Apartamento nuevo, muy cómodo y con mobiliario de lujo, diseñado para una estancia acogedora y elegante. Ubicado en una zona tranquila de Las Tablas, a 7 minutos del parque y a 15 minutos de las playas. Dispone de camas muy cómodas con colchones de alta gama y sábanas de alta calidad hotelera para un descanso reparador. Cuenta con zona de coworking y TV con streaming. Cocina completamente equipada. Ideal para disfrutar con total tranquilidad.

LocationSleep qualityHospitality

Guest favourite

The outdoor area features a spacious infinity pool surrounded by a sun deck, complete with lounge chairs. Lush greenery and palm trees can be seen in the background, under a bright blue sky with fluffy clouds, creating a serene outdoor retreat.

Home in Pedasí

4.96 out of 5 average rating, 25 reviews

Villa La Jungla featuring a New Pool

Escape to this serene, private retreat just minutes from Pedasí, Playa Venao, and stunning beaches. Perfect for 4–8 guests, the home features spacious en-suite bedrooms with quality linens, a fully equipped kitchen, and a newly resurfaced infinity pool. Enjoy total privacy, comfort, and easy access to local adventures. Whether you're here to surf, explore, or relax, this is your ideal home base for a peaceful and memorable stay.

LocationValueView

Top Guest favourite

Place to stay in Pedasi

4.88 out of 5 average rating, 17 reviews

Una Buena Caminata-Pedasi

Una Buena Caminata is a quiet, spacious villa designed as a retreat base—where days unfold slowly and logistics are handled with care. Set between the town center and Playa El Arenal, the gateway to Isla Iguana, the property offers both connection and seclusion in equal measure. This is not a resort and not a hands-off rental. It is an intentionally curated space for guests who value privacy, ease, and thoughtful living.

FamilyLocationCleanliness

Guest favourite

The exterior of a two-story adobe house is depicted, surrounded by lush green foliage and palm trees. A spacious porch extends from the house, featuring seating options under a lovely tiled roof. Natural materials blend seamlessly with the earthy landscape.

Earthen home in playa el arenal pedasi

4.96 out of 5 average rating, 183 reviews

Earth House Pedasi Experience

Welcome to the Earth House. This space is destined to give you the experience of spending your vacations in a Eco House with all the amenities and facilities of a ¨Regular Home¨. Why Eco? This house is made with 95% adobe and with natural materials from the surroundings like rock and wood. Everything is handmade for this unique space. It is a wonderful experience to share with family and friends.

ValueFamilyBarbecue