
House holiday rentals in Santo Domingo
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Top-rated house rentals in Santo Domingo
Guests agree: These houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for Santo Domingo house rentals
House rentals with a pool

Tropical Townhouse Living
Everything is excellent and highly recommended.

Yellowfin Casa 3
Charlie is a fantastic host, the home is awesome, and we will definitely be back to stay again in the future!!

Beautiful Home Directly on Playa Venao Sleeps 8-10
We had an incredible stay at Casa Azul! The location is perfect with a beautiful pool and the beach right out the door. It’s walkable to the main restaurants and stores, but quiet and private that you can really relax. The house really helped all of us relax and enjoy our time in Venao. Thank you! Will definitely be coming back again!

Modern Beach Home with pool and hot tub
This is one of the only places where the pictures didn’t do the home justice. It was a beautiful home! Hosts are great. Highly recommend.

2/2 Private Oasis Pedasi's best location & rental!
ABSOLUTELY EXCELLENT PLACE! I LOVE PEDASI!! And Ryan's home felt like home: Thank you so much for that!!! I PLAN to return and look forward to staying here again!!!

Steps from Ocean: Couple's Getaway Private Villa
Excellent villa everything was spotless and clean close to the rest and pool super recommended 100%

NINA HOUSE, a spacious and cool house in Chitré.
Our stay at Nina House was very warm, from the place, the House and Ninoska attentions were excellent Full recommended… We would not hesitate to return.

Casa Del Amor in Pedasi, Panama Oceanfront paradise
Casa del Amor was everything we hoped for and a little more. We stayed here with a group of 8 and had more than enough room for everyone to do what they wanted. The pool overlooking the beach was fantastic and the beach felt almost private! The area felt safe and everyone we met was incredibly welcoming. We can’t wait to come back!!!! Thank you for sharing your home with us to make some great memories!!!
Weekly house rentals

La Hacienda Ojo de Agua * Family & Friends Getaway
Had a wonderful and enjoyable time at the house. Pool was refreshing, house was accommodating, and made a very wonderful connection with Tamara. She gave us a warm welcome. Thank you for sharing your home and all the extras you did for us Tamara. We will miss our chats.

rainbow in the redelefant farm
I recently had the pleasure of visiting this incredible destination, and it exceeded my expectations in every way. From the moment I arrived, I was enveloped in kindness, passion, and warmth. The staff's compassionate conversations and genuine welcomeness made me feel right at home. What struck me most was the serene environment, which reminded me that life is full of wonderful surprises. I left feeling refreshed and inspired, already looking forward to my next visit. The thoughtful gifts and delicious food were delightful touches, showcasing the attention to detail and care that goes into creating an unforgettable experience.

Family house/outside modern living
Michell is an excellent host! He was always looking out for us. As for the house, it is just what we needed, cozy and maintains an excellent location, very central, 100% recommended.

Minimalist House In Chitre
Is the second time we stay at Raul’s place and as always is impeccable and a great option for us. It is near a supermarket, near downtown Chitre. The host is very responsive, has ran out for the water heater and almost immediately Raul had someone there fixing it for us. The place is comfortable and good to have a full kitchen to prepare meals, the backyard with a seating area to relax after a long day. Raul thank you again for a great place for our holiday vacation! Until the next time!

Casa Luna 2 bdrm 2 bath walk to square!
Sweet little spot walking distance to Pedasi stores and restaurants! With being so close, the space was still very peaceful! The communication with Robert and Daniel was excellent and very easy. Instructions for self check-in made it so easy! thanks for the great stay and great location!

La Casita 4BR Spacious Private Paradise w/pool
Our stay at this house was simply spectacular. The ocean view is breathtaking, every sunrise and sunset look like a dream. The house is beautiful, with a neat decor and a cozy atmosphere that makes you feel in a private paradise. Also, the host was incredibly responsive and friendly, making sure everything was perfect for our stay. Definitely a place we want to go back to. 100% recommended!

Cozy country-style house.
Excellent location easy to access, the host is very friendly, everything is completely and spacious.

Chitré: Weliss's House
Excellent house, central and José Vidal's service was the maximum. Recommended full. I would definitely stay again.
Private house rentals

Ocean View, Ocean View El Ciruelo
The house was perfect for my friends (2 couples). We had such an amazing time. The view is breathtaking, the accommodations were comfortable, Carolina was a responsive and helpful host, the area is great for both surfers and non-surfers. Carolina suggested we eating at Pesca del Dia and we had delicious super fresh locally-caught fried fish and ceviche. We loved having visits from the resident doggies and kitties. We spent a lot of time at the pool doing yoga, swimming, hanging out looking at the ocean, and stargazing. We were so well taken care of that I hope to come back to this little slice of paradise again someday. Thanks for hosting us!

Villa Carola, Las Tablas.
The house is big, comfortable and super central. The host was very friendly and attentive. ¡100% recommended!

Casa Iguana 2 - 2 queen beds, 2 sets bunk beds
Great spot and service. The only negative was a sporadic power outtage. For the rest all nice 👍🏽

Make yourself at home
These are the kinds of cases where the home is a true reflection of the host’s great attention to detail, professionalism, and good care. The place was spotless, the location and other details were accurately described by the host, and even better, the service was VERY responsive, kind, and genuinely concerned with making sure their guests had the best possible experience. Grateful for the wonderful experience and attention from the hosts, my family and I highly recommend their services and you can undoubtedly place your trust in the hands of Karla and María.

Spacious Condo Heart Playa Venao
Ana is the best host I’ve met! The house was clean and perfect for cooking and rest. A bit far from the center, 7-10 minutes walk. Very recommend.

Ibiza House
The stay was very good, some things that can be improved like: The cleaner pools, some problems with the doors when opening. Otherwise very good for its price and number of people who can stay.

Centric and well equipped with capacity 10 people
A very comfortable and clean house. The photographs and description are according to the place. Very good service and communication with Amarilis.

House in Pedasí, near beaches
The house is big, very good location in the village of Pedasi and was super clean, this is always important to me. The host was always attentive to my inquiries and gave me recommendations on the beaches and tour to Isla Iguana :) The only improvement comment would be that they explain better how to open the car gate, it cost us a little but then we found the trick.
Quick stats about house rentals in Santo Domingo
Total rentals
20 properties
Nightly prices starting at
$50 NZD before taxes and fees
Total number of reviews
240 reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
20 properties allow pets
Rentals with dedicated workspaces
10 properties have a dedicated workspace
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