
House holiday rentals in Seneca
Find and book unique houses on Airbnb
Quick stats about house rentals in Seneca

Total holiday rentals
Explore 40 holiday rentals in Seneca

Nightly prices starting at
Seneca holiday rentals start at $87 NZD per night before taxes and fees

Verified guest reviews
Over 1,880 verified reviews to help you choose

Family-friendly holiday rentals
30 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
40 of Seneca holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wi-Fi and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
Top-rated house rentals in Seneca
Guests agree: These houses are highly rated for location, cleanliness and more.

Hanover Haven 3 BR/2 Bath
Hanover Haven is located close to all you need! Clemson University is only 3 miles away. There are 3 full grocery stores within 5 minutes. Lake Keowee access and marina all within 5 miles. The Gathering space is such a great place to have family fun! There are card games and large TVs with multiple streaming platforms. We are also working on a great outdoor space that will include a grill and sail shade ready for the summer. There is also an RV on the property that is an AirBNB with privacy.
FamilyValueCheck-in
4.95 out of 5 average rating, 146 reviews
Dujardins Keowee Waterfront Home
2 night min. Deep water lot on Lake Keowee with double dock, and tons of entertaining space. On the main level, the great room/dining room is open to the kitchen. 4 bedrooms total, 3 king bedrooms (2 on first floor), 1 king and a bunk room with 2 doubles and 2 singles. A canoe, 2 paddle boards and 2 double kayaks included. Shuffleboard, foosball, outdoor Ping-Pong, board games and two person pac-man game, with additional 60 games! towels and linens included! Pickleball/tennis 10 min away!
LocationFamilyLaundry
4.93 out of 5 average rating, 166 reviews
Private lake setting close to Clemson University
House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.
FamilyValueNearby
4.95 out of 5 average rating, 208 reviews
House on Lake Keowee swim beach in cove w/ Dock
This two story home is located at the end of a very quiet cove with plenty of water. The beach has a fresh 6 inches of sand installed for the lake season. The walk to the lake is very short on an almost flat surface. The home will accommodate a family up to six people. The house has two floors. The main floor has a large living room with plenty of comfortable seating and satellite TV service provided. The entire main floor has hard woods along with the Master Bed Room and bed room #2.
FamilyValuePets
4.84 out of 5 average rating, 283 reviews
Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.
FamilyLocationBathroom
4.94 out of 5 average rating, 302 reviews
Singing Pines Cottage
Right among the pines of South Carolina you will find our cottage. It's 5 minutes from the Historic Ram Cat Alley with Live Outdoor music every Thursday Night (Apr.-Oct.), Shopping, Boutiques, Restaurants, Breweries, and Coffee Shops. It's only 12 minutes from Clemson University, and a short drive to Lake Keowee, Lake Jocassee, and Lake Hartwell. This area is home to numerous Waterfalls, Hiking Trails, and good southern barbecue. We do not host work crews.
LocationFamilyHiking
4.98 out of 5 average rating, 102 reviews
The Cottage
Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.
FamilyLocationTV
5.0 out of 5 average rating, 144 reviews
Shady Rest
As you enter the screened in front porch you will instantly relax, experience a peaceful and quiet tree lined front yard. The house has plenty of shade and old oaks, built in 1935 has the charm of visiting great grandmother’s farm house without the wallpaper. Large side deck with grill, hot tub and plenty of shaded sitting. Side yard has a fire pit for evening campfires and roasting marshmallows. The house has an open floor plan.
FamilyLocationRiver
4.94 out of 5 average rating, 139 reviews
Getaway on Lake Hartwell: Pontoon Rental, Clemson
Our 3 bedroom house is located on Lake Hartwell and is just a 15 min drive to Clemson University. You can enjoy access to the dock and beach which are a quick golf cart ride away. We have paddle boards on the dock and kayaks, coolers, bagged ice, fishing poles etc upon request. Off the back of the detached garage there’s a furnished screened-in deck with a grill that overlooks the end of the cove and fire pit below.
LocationFamilyAccuracy
4.94 out of 5 average rating, 146 reviews
5 Min to Clemson | Large Driveway & Self Check-In
Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.
ValueLocationComfort
4.96 out of 5 average rating, 151 reviews
The House on Oak Grove
Enjoy your time spent in this spacious and peaceful pet friendly space. Nicely appointed with everything you need for a short or long term stay. Ten easy miles to Clemson and 3 miles to SWU. Besides the open living space the house has a screened porch and accomodates 4 with 2 bedroom & 2 adjoining baths. The home includes washer & dryer, coffee bar, granite countertops, and microwave.
LocationFamilyCheckout
4.96 out of 5 average rating, 168 reviews
Perfect Lake Hartwell Getaway! Gorgeous Views!
Lake living at its best: Amazing views, deep water with a perfect location steps from the shoreline and for you Tiger fans this property is ten minutes from Clemson. Waterfront point lots that are this close to the water are extremely rare. This house is only a very short ride from Clemson Marina and the Walker Course. Gorgeous Sunsets from the dock!
LocationFamilyHiking
4.96 out of 5 average rating, 107 reviewsPopular amenities for Seneca house rentals
House rentals with a pool

Keowee Key Luxury Condo - Stunning Views!
LocationValueLayout
4.98 out of 5 average rating, 170 reviews
Lake house w/ a pool and Pickleball court
ValueFamilyPool
4.82 out of 5 average rating, 131 reviews
Pet-Friendly Retreat • Hot Tub • Fenced Yard
LocationValueOutdoor spaces
4.99 out of 5 average rating, 168 reviews
Clemson- 5 Min | Pool | Hot Tub | Epic Game Lounge
ValueLocationDecor
4.96 out of 5 average rating, 26 reviews
Lazy Dayz - on Lake Keowee w/dock, pool & hot tub
FamilyLocationBathroom
4.92 out of 5 average rating, 60 reviews
A+ Keowee Kustom!*NO Dock!
FamilyLocationOutdoor spaces
5.0 out of 5 average rating, 21 reviews
* Keowee Key* Lake* Fireplace*Golf*Tennis*Gym*
FamilyLocationSleep quality
4.78 out of 5 average rating, 40 reviews
Clemson Games + ON Lake Hartwell
LocationFamilyView
4.86 out of 5 average rating, 21 reviewsWeekly house rentals

Peaceful Lake Keowee Waterfront Home ~Near Clemson
FamilyValueBathroom
4.86 out of 5 average rating, 90 reviews
The Carriage House at South Townville
FamilyLocationWalkability
5.0 out of 5 average rating, 21 reviews
Cozy Modern Home Close Clemson
LocationValueIndoor spaces
4.98 out of 5 average rating, 50 reviews
Lakefront Mid-Century Dream Home / 3 mi to Clemson
ValueLocationLayout
4.94 out of 5 average rating, 78 reviews
Lakefront+Near Clemson+Dock+Kayaks+Putting Green
FamilyLocationTV
4.98 out of 5 average rating, 57 reviews
Johnsons Cove/Lakefront Retreat/Hot Tub/EV Charger
LocationFamilyBackyard
4.98 out of 5 average rating, 65 reviews
Sunrise Cove Lakeside Cottage - Newly built.
ValueLocationCondition
4.98 out of 5 average rating, 40 reviews
Forest Hills Retreat
LocationValueWalkability
5.0 out of 5 average rating, 13 reviewsPrivate house rentals

Sweet Tea Retreats
FamilyLocationSleep quality
4.94 out of 5 average rating, 17 reviews
Lakefront Home w/Deep Water Dock 20 min to Clemson
LocationFamilyKitchen
4.97 out of 5 average rating, 32 reviews
Tee House... waterfront on beautiful Lake Keowee
ValueLocationLayout
4.97 out of 5 average rating, 76 reviews
25 minutes from Clemson, newly remodeled home!
ValueFamilyAccuracy
5.0 out of 5 average rating, 42 reviews
Lakefront Getaway~Dock~Fire Pit~Kayak & Games!
LocationFamilyKitchen
4.96 out of 5 average rating, 25 reviews
Keowee Lakefront Home | Hot Tub, Kayaks, Dock!
LocationFamilyCheck-in
4.91 out of 5 average rating, 69 reviews
No cleaning fee farmhouse lake keowee near Clemson
ValueLocationSleep quality
4.93 out of 5 average rating, 61 reviews
Lakefront Oasis on Lake Keowee
FamilyLocationOutdoor spaces
5.0 out of 5 average rating, 33 reviewsWhen is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $297 NZD | $349 NZD | $330 NZD | $339 NZD | $442 NZD | $615 NZD | $285 NZD | $411 NZD | $379 NZD | $339 NZD | $405 NZD | $314 NZD |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Destinations to explore
- Nashville Holiday rentals
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- Myrtle Beach Holiday rentals
- Gatlinburg Holiday rentals
- Charlotte Holiday rentals
- Pigeon Forge Holiday rentals
- Savannah Holiday rentals
- Charleston Holiday rentals
- Asheville Holiday rentals
- Hilton Head Island Holiday rentals
- North Myrtle Beach Holiday rentals
- Clemson University
- Table Rock State Park
- Helen Tubing & Waterpark
- Black Rock Mountain State Park
- Gorges State Park
- Tallulah Gorge State Park
- Bell Mountain
- Devils Fork State Park
- DuPont State Forest
- Unicoi State Park and Lodge
- Chattooga Belle Farm
- Bon Secours Wellness Arena
- Fred W Symmes Chapel
- Jump Off Rock
- Falls Park On The Reedy
- Jones Gap State Park
- Fluor Field at the West End
- Peace Center
- Whitewater Falls
- Anna Ruby Falls
- Carl Sandburg Home National Historic Site
- Dry Falls
- Smithgall Woods State Park
- Soquee River





