Guesthouse holiday rentals in South Carolina

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Top-rated Guesthouses in South Carolina

Guests agree: These guesthouses are highly rated for location, cleanliness and more.

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Top Guest favourite
A gravel path meanders through a grassy area, flanked by low shrubs and tall trees, creating a serene and natural environment. Soft sunlight casts a gentle glow over the scene, highlighting the rich green foliage and the open field stretching out in the distance.
Guesthouse in Abbeville
4.97 out of 5 average rating, 354 reviews

Scenic Loft in the Woods

Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!

Top Guest favourite
A charming studio cottage is nestled among lush greenery, surrounded by tall trees. Steps lead to the entrance, framed by vibrant flower beds in soft pink hues, enhancing the inviting garden setting.
Guesthouse in Spartanburg
4.99 out of 5 average rating, 467 reviews

The Cottage in Spartanburg

This charming & private studio cottage is located in Spartanburg's downtown historic district Hampton Heights. Guests will find a comfortable foam mattress sofa bed (no bars or springs), full bathroom, closet, & complete kitchen amenities. Located less than a mile from restaurants, bars, m-league ball park & shops of Downtown Spartanburg, and close to Converse Univ., VCOM, and Wofford College, this cozy studio cottage is the perfect place to rest your head after a busy day visiting the Upstate.

Top Guest favourite
An airy loft space features a suspended wooden swing, inviting relaxation under the high, timbered ceilings. Natural light streams through large windows, illuminating cozy furnishings including a bed and a dining area with a wooden table. Unique decor elements enhance the overall character.
Guesthouse in Summerville
4.98 out of 5 average rating, 728 reviews

★Delightful guest house near historic plantations★

Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*

Top Guest favourite
A bright living area features a white sofa adorned with blue and white decorative pillows, alongside a leather recliner. Two woven tables sit in front of the couch on a textured rug. A flat-screen TV and kitchen are visible in the background.
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 313 reviews

Upscale Couple's Escape | Beach & Downtown CHS

Perfect getaway for anyone looking to relax and enjoy the beautiful Charleston beaches. We maintain the highest standards for luxury - including curated interior design touches to make you forget reality and enjoy some much needed R&R time. The Pump House is the ideal place to escape to and enjoy the outdoors, local restaurants, breweries, parks, and, of course, beaches! Our reviews speak for themselves - Always 5 stars and many return guests! Permit #ST250099 | Business License #20122954

Top Guest favourite
The exterior of the cottage showcases a striking black and red color scheme. A welcoming entrance features double French doors flanked by large windows. Two comfortable Adirondack chairs are positioned on a brick patio, surrounded by lush greenery and potted plants, inviting relaxation.
Guesthouse in Sumter
5 out of 5 average rating, 106 reviews

The Little Cottage, Stateburg

Take it easy at this unique and tranquil getaway. The Little Red Cottage features a small bedroom with a double size bed and a closet, a spacious living room with sofa/roku TV and computer desk, and a bathroom with shower. It is nestled on 6 serene acres, among massive windswept Live Oaks dripping with Spanish moss, Palmettos, azaleas, camellia, magnolias and creape myrtle, yet so conveniently close to Shaw Air Force base, 30 mins to Columbia and Camden, close to all Sumter's attractions.

Top Guest favourite
The serene cottage is surrounded by lush greenery and colorful flowers, with pink azaleas and white dogwoods blooming prominently in the foreground. A charming red barn is nestled among the trees, enhancing the peaceful rural setting.
Guesthouse in Greenville
5 out of 5 average rating, 438 reviews

The Cottage at Old Oaks Farm

Built in the early 1900's, this serene cottage is located approximately one mile from Furman University at the base of Paris Mt. It has been lovingly improved, but the floors are a bit slanted and no corner is exactly square. Located in a neighborhood on a five acre farm, it consists of three large rooms, comfortably furnished and lots of natural light. The cottage is convenient to downtown Greenville(5 miles),Travelers Rest, Furman, and the Swamp Rabbit Trail. No pet fee or cleaning fee.

Top Guest favourite
The two-story guest house features a bright red exterior with a metal roof and two front balconies. Lush green grass surrounds the building, and scenic pastures can be seen in the background, emphasizing the rural setting. Multiple windows provide ample natural light.
Guesthouse in Windsor
4.97 out of 5 average rating, 102 reviews

Horse Farm in Aiken, SC

Spacious, private guest house with views on a 17-acre entirely fenced horse farm located just 14 miles from Aiken, SC and 30 miles from Augusta, GA (Masters). Our equestrian community exudes southern charm; the perfect, peaceful retreat and horse country getaway. Near to historic Downtown Aiken & Hitchcock Woods. This family-friendly farm is ideal for short, extended or corporate stays. Have horses? There's a barn with 4 stalls and 7 fenced pastures for horse turnout. Separate fee.

Top Guest favourite
The studio apartment features a cozy sleeping area with a spacious bed framed by warm-colored bedding. A leather sofa and a blue accent chair are arranged in the living space, complemented by side tables and soft lighting creating a calm ambiance.
Guesthouse in Columbia
5 out of 5 average rating, 153 reviews

Restful Refuge

Restful Refuge is a renovated one-bedroom studio apartment that includes a full kitchen and full bath downstairs to our home. For your stay with us you will have a private entrance. We are located just minutes from Downtown Columbia but secluded in a small community on a pond. Our desire is to provide a place to help you unwind & rejuvenate during your time in Columbia. Whether you are in town for business or pleasure, we would love to share our Restful Refuge with you.

Top Guest favourite
A spacious bedroom features a black metal bed frame adorned with white bedding. Two stylish chairs are positioned beside large windows offering views of the surrounding landscape. A wooden dresser and a woven area rug add elements of comfort and warmth to the room.
Guesthouse in Charleston
4.99 out of 5 average rating, 219 reviews

Large Guesthouse with Private Dock & Marsh Views

This newly built carriage house is separate from the main house. The cottage is about 1,200 sqft so it very open and spacious and great views of marsh and our tidal creek. We have a separate work area with desk and a massive dinning table if you need more room to work or to gather with friends. Full kitchen, washer and dryer, massive shower, the list goes on. You may not want to leave! Feel free to go sit and have coffee or cocktails on the dock. PERMIT# OP2024-04998

Top Guest favourite
The exterior of the guest house is showcased, featuring a sturdy wooden door adorned with decorative hardware. The structure is framed by light-colored stone walls and has two small windows flanking the entrance, with a sloped roof that complements the rustic design.
Guesthouse in Spartanburg
5 out of 5 average rating, 114 reviews

The Lodge at Pythian Park

Situated in a 3+ acre gated compound surrounded on three sides by Fairforest Creek, our guest house feels like a mountain hideaway yet it's only a 3 minute drive to downtown Spartanburg. Enjoy the private patio overlooking the creek to relax or prepare a meal on the gas grill. Dogs are welcome, and we have 2 very social dogs that you will probably encounter during your stay. There's ample parking for vehicles and room to roam and enjoy the park-like setting.

Top Guest favourite
A newly-built guest cottage is depicted, elevated on pilings and surrounded by lush greenery. Light-colored siding is complemented by green shutters. Steps lead up to a welcoming porch with a railing, providing access to the spacious entry and large windows that invite natural light.
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 213 reviews

Stunning Couples Cottage with Creek Dock!

You will fall in love with this stunning, newly-built guest cottage nestled under the canopy of a majestic 400-year-old live oak tree! Providing ultimate comfort, convenience and serenity, this is the perfect place to launch your Charleston adventure – 10 minutes to Shem Creek, & 15 minutes to Sullivan's Island or Downtown Charleston. PLUS, come enjoy our brand new dock on the creek! A picture-perfect spot to relax and enjoy the stunning Lowcountry scenery!

Top Guest favourite
A stylish living area features a green velvet sofa paired with a round wooden coffee table. Decorative items are placed atop the table, while a floor lamp provides soft lighting. Large windows allow natural light to illuminate the space, which is accented by framed artwork and a potted plant.
Guesthouse in Mount Pleasant
4.97 out of 5 average rating, 118 reviews

Old Village Guesthouse walkable, close to beach/DT

Location. Location. Location! It's trite, but it's true. You’ll be minutes from downtown Charleston and the beach at Sullivan’s Island when you stay with us in the historic Old Village of Mount Pleasant. Walk to some of the town’s best restaurants and waterfront bars or seize the moment to relax in our breezy, modern guest house in one of the oldest, most beautiful neighborhoods in the country. STR permit number: ST250100 Business license number: 20122246

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