
Hotels in South San Francisco
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Top-rated hotels in South San Francisco
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Convenient location in Union Square- Free wifi
Private HOTEL room w/private bathroom, timeshare hotel property at THE DONATELLO in UNION SQUARE (sleeps 4) in the heart of San Francisco You are not obligated to attend a timeshare presentation. The front desk will require the following in order to get the room key: 1. Refundable security deposit $250 - credit card preferred Bank issued debit cards may be accepted. Sorry Chime, Netspend, Visa Gift etc are not accepted at this time for the deposit 2. Valid photo Government ID - must be 18+

Sophisticated Stay | Cable Cars Tours. Gym
Located on Market Street, Hyatt Regency San Francisco Downtown SOMA is a sophisticated destination hotel close to the city’s most innovatively stimulating sights. Attractions are just nearby: ✔Picturesque picnics at Golden Gate Park ✔Contemporary and modern paintings, photographs, sculptures and designs from the 20th century, all housed at SF MOMA ✔Postcard-worthy shots, at Golden Gate Bridge ✔Beaux-Arts wonder, the Palace of Fine Arts ✔Best views of San Francisco at Twin Peaks

Union Square Steps Away | On-Site Dining + Gym
Steps from San Francisco’s vibrant Union Square, The Marker blends over a century of hospitality with modern elegance. This boutique Beaux-Arts hotel offers curated amenities like PATH water bottles, FloWater stations, and a 24-hour state-of-the-art fitness center. Dine at Tratto, serving rustic Italian dishes and craft cocktails. With concierge service, curbside valet parking, and California Green Lodging certification, The Marker pairs timeless charm with contemporary comfort.

Book-filled Writer’s Alcove in the lobby
Channeling the spirit of the Beat Generation, every room at Hotel Emblem is a creative retreat featuring a writing desk with an inspiration board. Enjoy plush pillowtop beds with Italian linens, a 55" HD TV, and unique touches like a meditation bowl, typewriter, and coloring books. Thoughtful amenities include in-room coffee and tea, ROIL bath products, and high-speed internet. With pet-friendly options and hotel bikes, your San Francisco stay is both inspiring and comfortable.

Bay Area Escape | Hotel Room. Free Breakfast
If you plan to explore the Bay Area, The Millwood Inn & Suites is a great jumping-off point. This quaint hotel is located in Millbrae, California, only minutes from Bay Area attractions such as the Golden Gate Bridge. It is also only a six-minute drive from San Francisco International Airport, perfect for those flying in! Be welcomed into a world of comfort and convenience after a long day of exploring California's best. ✔ Free breakfast ✔ Free parking ✔ Fitness center

Near Stanford Univ + Breakfast. Kitchen. Pool.
Stay minutes from Stanford University, Google, and downtown Palo Alto at Residence Inn Palo Alto Los Altos. Enjoy spacious suites with full kitchens, separate living areas, and free Wi-Fi. Start your day with a complimentary hot breakfast, unwind by the outdoor pool, or keep up with workouts in the fitness center. Steps from shopping, dining, and tech hubs, this pet-friendly hotel offers the perfect blend of convenience, comfort, and Northern California charm.

Fun Escape | Happy Hour. Game Room. Location.
Axiom Hotel, a 4-star establishment in San Francisco's city center, is an ideal accommodation for those looking for a fun hotel to stay in during their trip to SF. It features a fitness center and a game room. Guests can also venture out to see prime attractions nearby, like Moscone Center and the Ferry Building. ✔ Fitness center ✔ Robot-delivered room service ✔ Pet-friendly ✔ Arcade games ✔ Cafe on-site ✔ Breakfast, lunch, dinner, boba and a full bar

Anchor Studio 225
The Monroe Residence Club is a residential hotel located centrally in the heart of San Francisco with public transportation at our doorstep and local shops and businesses nearby. It is conveniently located just a block from Whole Foods, blocks from a the iconic Lafayette Park, within walking distance of several hospitals and more! The Monroe offers 24-hour front desk security, breakfast and dinner on-site, as well as common areas for congregating.

Nob Hill Inn 1 Bedroom Apartment
This 1-bedroom apartment with a living room in the heart of Nob Hill offers the perfect blend of comfort and convenience. What makes this space special is the combination of privacy and space, featuring a separate living area for relaxation and a well-appointed bedroom for restful nights. Located in the prestigious Nob Hill neighborhood, you’ll be steps away from top San Francisco attractions, iconic landmarks, and local dining gems.

Silicon Valley Inn, 1 Full Bed
Fuss-free motel-style setup right off Route 82, a 5-minute stroll from Belmont train station and 3 miles from Hiller Aviation Museum. San Mateo, San Carlos and Redwood City are easily accessible via CalTrain. Your room charge will be paid prior to your arrival. The remaining balance of taxes (12% City Transient Tax) will be charged upon arrival. A refundable security deposit of $XX will also be collected.

The Clift Royal Sonesta San Francisco
Experience the perfect blend of historic charm and modern style in our newly renovated deluxe king room. Relax in a plush king bed, enjoy a spa-inspired rainfall shower, and stay productive at the sleek work desk. With premium amenities like a mini-bar, Keurig coffee maker, streaming TV, and complimentary WiFi, your stay is both luxurious and convenient.

Restless City | Cable Cars Tours. Historic Sites
While our views are amazing, it’s the city’s energy and restless spirit of transformation that quickens your heartbeat and gets your mind spinning. At Stanford Court Hotel, we’ve crafted an experience that plays off this buzzing atmosphere.
Popular amenities for South San Francisco hotels
Family-friendly hotels

Inn at the Opera Resort San Francisco

Bed in 6-Bed Mixed Dorm with AC

1 Bed Female Dorm w/Private Bath

Easy jaunt to the famed cable cars of Union Square

Next to the quiet, scenic Sutro Heights Park

Single Bed in 2 Bed Male Capsule Room

Minutes to Airport | Pool + Free Breakfast

King Room | La Quinta Hayward | Breakfast Included
Hotels with a pool

Hotel Fiona

Near SJC | Pool. Gym + Free Breakfast & Parking

Near Great America Theme Park + Breakfast & Pool

Berkeley Marina Views + On-site Dining. Pool. Gym.

Near Oracle HQ | Free Breakfast + Full Kitchen

Experience All That Silicon Valley Has To Offer

Riu Plaza Fisherman's Wharf

Boutique stay tucked along Matadero Creek
Hotels with a patio

Club Wyndham Suites at Fisherman’s Wharf

Unique Hotel Inn at the Opera

Upscale Urban 2bd San Francisco

(Full Bed) Room

1BA Studio at Donatello

Hotel at Fisherman Wharf 1 Room Sleeps 4 People

1 King bed in boutique hotel

2 BR at Fisherman's Wharf
Quick stats about hotels in South San Francisco

Total holiday rentals
Explore 50 holiday rentals in South San Francisco

Nightly prices starting at
South San Francisco holiday rentals start at $238 NZD per night before taxes and fees

Verified guest reviews
Over 310 verified reviews to help you choose

Family-friendly holiday rentals
20 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 40 rentals that welcome pets

Holiday rentals with a pool
20 properties feature pools

Rentals with dedicated workspaces
50 properties have a dedicated workspace

Wi-Fi availability
50 of South San Francisco holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across South San Francisco rentals
Destinations to explore
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- Rentals with breakfast South San Francisco
- Rentals with an EV charger South San Francisco
- Condo rentals South San Francisco
- Rentals with a washing machine and dryer South San Francisco
- Rentals with a hot tub South San Francisco
- Family-friendly rentals South San Francisco
- Rentals with pools South San Francisco
- Rentals with outdoor seating South San Francisco
- Private suite rentals South San Francisco
- House rentals South San Francisco
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- Fitness-friendly rentals South San Francisco
- Rentals with a patio South San Francisco
- Rentals with a fireplace South San Francisco
- Rentals with a fire pit South San Francisco
- Pet-friendly rentals South San Francisco
- Hotel rooms San Mateo County
- Hotel rooms California
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- Moscone Center
- Stanford University
- Golden Gate Park
- Muir Woods National Monument
- Oracle Park
- Golden Gate Bridge
- SAP Center
- Twin Peaks
- Pier 39
- Henry Cowell Redwoods State Park
- University of California-Berkeley
- Six Flags Discovery Kingdom
- Montara Beach
- Palace of Fine Arts
- Levi's Stadium
- Winchester Mystery House
- Bolinas Beach
- California’S Great America
- Painted Ladies
- Davenport Beach
- San Francisco Zoo
- Googleplex
- Rodeo Beach
- Duboce Park




