Holiday houses in Depew

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Top-rated holiday rentals in Depew

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A cozy sleeping area features a spacious bed with a light-colored coverlet. Decorative pillows are arranged at the head of the bed, complemented by bedside tables and lamps. Natural light filters through sheer white curtains, enhancing the calming ambiance of the room.
Guesthouse in Cheektowaga
4.81 out of 5 average rating, 159 reviews

Warm & Cozy private Guesthouse/ Entire place.

Hi there! This is Aklima and Farhad, and we’re thrilled to have you stay at our guest house. It’s connected to our house, but both have their own private entrances. Just a friendly reminder, you might spot our kids playing in the backyard, so please be mindful of that. We love living here and meeting new people, which is why we started Airbnb. We’re committed to providing the best hospitality at an affordable price. This place is surrounded by nature and in a peaceful area! Enjoy your stay!

Top Guest favourite
A living area is displayed, featuring a dark sofa alongside a patterned armchair. A decorative area rug covers the wooden floor. The background shows a kitchen space with bar seating and modern appliances, contributing to a welcoming atmosphere.
Apartment in Cheektowaga
4.94 out of 5 average rating, 231 reviews

Close to Niagara Falls and Airport, Mall nearby

Niagara Falls is only 30minutes away.Very nice neighborhood. 4minutes from Galleria Mall.Plus many more stores nearby.Many places to eat and have some drinks! Sleeps-5 plus we have a clean pack and play for your little one. Has own keypad entrance. Full sleeper sofa in living room. One bedroom has a queen bed and tv. The 2nd bedroom has a twin bed and offers tv and a workspace. Very clean! Kid friendly and pet friendly. Pets can do their business out front. There are dogs that use the back yard.

Superhost
A spacious living area features two white sofas adorned with patterned cushions and a glass coffee table. Task lamps provide soft lighting, while large windows with white blinds allow natural light. A decorative rug complements the room's neutral tones, and a desk with a chair is situated in the background.
Apartment in Cheektowaga
4.83 out of 5 average rating, 107 reviews

Cozy Home - Safe Area & close to Everything

Relax with your full family at this peaceful place to stay for who are traveling to Buffalo. Place is PET FREE. Keep it simple at this peaceful and centrally-located place. Closed to Airport, Downtown, Gallery Mall. Also you will find walking distance restaurants, Central Park, Hospital, Library etc. You will feel safe because of the quiet & secure; Nice and clean area and close to everything. Please DON’T book if you are LOCAL RESIDENTS. Send message w/ purpose of booking for pre-approval.

Top Guest favourite
A cozy bedroom features a wooden sleigh bed with a plaid comforter. A decorative lamp sits on a nightstand beside the bed. A trunk labeled 'LOVE' is placed at the foot of the bed, and a window with a checkered valance allows natural light to filter in.
Guest suite in Lancaster
4.98 out of 5 average rating, 186 reviews

"The Suite Spot", Adorable apartment with deck

Kick back and relax in this calm, stylish space. This second floor apartment boasts a newly remodeled bathroom, a full kitchen, a comfortable bedroom perfect for two & a cozy sitting area with chairs that convert into twin beds. It also offers off street parking for one vehicle & a private entrance on the deck. It's a perfect place to relax & enjoy the summer & fall. Along with our dog Toby & our cat Taffy who will welcome you (but will not be a bother) we invite you to enjoy our home.

Superhost
A living area features a wall-mounted television above a rustic wooden table. A small ladder shelf stands to the left, adorned with decorative items. The kitchen area is visible in the background, showcasing wooden cabinets and coffee-making equipment.
Apartment in Depew
4.8 out of 5 average rating, 410 reviews

The Shecave - 2 Bedroom Apt

This is perfect for your staycation or for a cozy pit stop. If you’re looking for a short term, no frills, respite, or workplace area, this is the place for you. This is not intended as a party house. Plenty of take out, pick up, or delivery of food. We PRIDE ourselves on the CLEANLINESS of our spaces. Great for a visit to Niagara Falls. Close to Galleria Mall. Quiet and safe neighborhood. **Please be at least 25 book.** **Photo ID will be required from you after booking.**

Top Guest favourite
An open living space features a round wooden dining table set for two, accompanied by a decorative plant. A gray couch is positioned to one side, with soft light illuminating the area. The room connects to the kitchen and a bathroom area is visible in the background.
Guest suite in Buffalo
4.99 out of 5 average rating, 131 reviews

Carriage house 1-bedroom at Glen Falls

Make yourself at home in this clean 1-bedroom upper apartment in the village of Williamsville! Just a short distance from everything, including the Buffalo Airport, some of the best restaurants/pubs WNY has to offer, Niagara Falls, & downtown Buffalo. All basic amenities are provided: 55" Smart-TV, WIFI, full bathroom, full kitchen including a coffee station, stove, refrigerator, and microwave. Private entrance & driveway. Self check-in. Close to I-290 (Exit 7 Main Street)

Guest favourite
A living area is shown with a light-colored sofa and a brown ottoman placed in front. A dark armchair with a patterned cushion adds contrast. A tall green plant is positioned beside a window, enhancing the natural light in the room. Neutral wall colors contribute to a calm atmosphere.
Apartment in Depew
4.87 out of 5 average rating, 23 reviews

Clean + Efficient! Airport - 10 Min Downtown - 20

PLEASE READ ALL LISTING DETAILS Great for 1-2 people traveling for business or visiting family and friends. Centrally-located and just a few blocks from The Lancaster Village, this location has shops, restaurants and parks nearby - and is only 10 minutes to the airport and thruway access. NOTE: Apartment is accessible only by a sharply pitched staircase with narrow steps and limited foot space. Individuals with balance or mobility limitations may find them challenging.

Guest favourite
A comfortable living area showcases two armchairs and a spacious sofa, all adorned with decorative pillows. A circular coffee table anchors the space, while a patterned rug adds warmth. Natural light filters through sheer curtains, softly illuminating the neutral-toned walls and accent artwork.
Apartment in Buffalo
4.89 out of 5 average rating, 123 reviews

Lovely 2-bedroom unit w/game room & free parking

Enjoy a stylish experience at this centrally-located place. Close to everything Buffalo has to offer. Be to the airport, Highmark stadium, down town Buffalo or Galleria mall in minutes. 2 bed 1 bath. One off street parking spot. House is located on a dead end street in a nice quiet neighborhood. Game room in the basement for the kids or adults, along with access to free washer and dryer. Free WiFi. Only a 28 minute drive to Niagara Falls.

Top Guest favourite
The studio features an open layout with a cozy seating area including a gray sofa and matching chairs. A dining table accommodates four, and a spacious bed is present in the corner. Natural light filters through the window treatments, highlighting the neutral color scheme.
Guest suite in Lancaster
4.91 out of 5 average rating, 187 reviews

Work or Play this is your Home Away!

Newly remodeled private studio with private entrance. Lots of parking space. 700sq ft.of living space for you to enjoy! Private balcony overlooking stunning backyard views with a pond. Only 13 min away from Buffalo airport! Shopping centers within a mile. Downtown Buffalo- 20 min. drive Flix Movie Theater- 2 min. drive New Era field- 20 min. drive Niagara Falls- 40min. drive Galleria Mall- 12 min. drive

Top Guest favourite
A cozy corner features a brick fireplace, framed by decorative plants and two lace-covered windows. A small wooden table stands beside the fireplace, adorned with a candle and vintage items. Nearby, a set of folding chairs is positioned next to a framed floral artwork.
Apartment in Buffalo
4.92 out of 5 average rating, 272 reviews

Peaceful, spacious apartment. Non-smoking.

Traditional South Buffalo lower in the Irish Heritage District. NOT suitable for children aged 1-12. NOT pet-friendly. 10 minutes from Canalside, Key Bank Center, Sahlen Field, Harbor Center, Riverworks and downtown. 20 minutes from Highmark Stadium. 30 minutes from Niagara Falls. Stumbling distance from the Buffalo Irish Center.

Guest favourite
The living room features a grey sofa and a brown leather couch, complemented by a wooden coffee table with decorative items. A framed artwork is displayed on the wall, and light streams through the windows with wooden trim, enhancing the cozy atmosphere of the space.
Home in Depew
4.9 out of 5 average rating, 31 reviews

Home sweet home away

Welcome to this newly remodeled bright gem in the village of Depew. Perfect for anyone who wishes to be close to most of what Buffalo has to offer! Spacious enough for a family and not too overwhelming for the traveling professional. This house has everything you need to feel like you are at home.

Top Guest favourite
The intimate porch is adorned with vibrant hanging flower baskets and softly lit torches. Lush greenery surrounds the area, enhancing the secluded atmosphere of the space. A glimpse of the tree-lined street is visible in the background.
Guest suite in Allentown
4.95 out of 5 average rating, 1,778 reviews

Buffalo's Allentown Area Apartment

The apartment itself is newly furnished and has its own private entrance. It is a one-bedroom apartment with a queen size bed. For an extra guest the living room is furnished with a roomy sofa bed. Intimate porch for morning coffee in the beautiful historic Allentown neighborhood.

Popular amenities for Depew holiday rentals

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