
Holiday houses in Downtown San Diego
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Quick stats about holiday rentals in Downtown San Diego

Total holiday rentals
Explore 2,500 holiday rentals in Downtown San Diego

Verified guest reviews
Over 116,800 verified reviews to help you choose

Family-friendly holiday rentals
760 properties offer extra space and kid-friendly amenities

Pet-friendly accommodation
Find 770 rentals that welcome pets

Holiday rentals with a pool
660 properties feature pools

Rentals with dedicated workspaces
1,370 properties have a dedicated workspace

Wi-Fi availability
2,490 of Downtown San Diego holiday rentals include Wi-Fi access

Popular amenities for guests
Guests love Gym, BBQ grill and Laptop-friendly workspace across Downtown San Diego rentals

4.7 Average rating
Downtown San Diego stays receive an average rating of 4.7 out of 5 from guests
Top-rated holiday rentals in Downtown San Diego
Guests agree: these stays are highly rated for location, cleanliness and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.

NEW Luxury 3BR HOUSE❤️of DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

Breathtaking Ocean, Bay, City & Petco Park Views
It’s all about the VIEWS in this Luxury Downtown residence featuring top Italian grain leather futuristic smart furniture with BREATHTAKING VIEWS of the Bay, Ocean, Petco Park from every room & the sunny balcony, Coronado Bridge, Point Loma and the City. Steps to Convention Center, Rady Shell, Seaport Village, Embarcadero, and Gaslamp Quarter with restaurants, music venues, coffee shops, rooftops, and sprawling nightlife. Little Italy, Balboa Park, San Diego Zoo, Beaches and Shopping nearby.

BEST LOCATION in all of Little Italy & downtown!
Location, location, location! Can't get any closer to the bustling Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. One of the only houses in all of downtown! This modern luxury home is just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & San Diego Zoo! All the frills: ++ Prime location! 98/100 Walker Score rating ++ High-speed internet, Netflix & smart TV ++ A/C ++ Super Host 5-star service

Calm Luxury Penthouse Getaway With Panoramic Views
Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

Gorgeous 2Bd Corner Bungalow in Little Italy
Little Italy Bungalows are located in the heart of San Diego’s most popular restaurant and entertainment district, Little Italy. Just one block from India Street, Farmer’s Market, and minutes from downtown, Balboa Park, airport, and harbor & beaches. This is a delightful neighborhood, steeped in local history and culture, and popular for dining and exploring. Little Italy Bungalows is perfect for couples, families, business travelers, convention-goers, single travelers and adventurers.

Kettner Row | Staycation-Featured Icon
Welcome to Kettner Row, a rare architectural masterpiece featured on Staycation Sports, an Emmy-winning show on the Destination Channel! Located in the heart of Little Italy—one of San Diego’s most desirable neighborhoods—and designed by renowned architect Jonathan Segal, FAIA. This detached row home is situated in the award-winning Little Italy Neighborhood Developers block (LIND). This modern home features dual master suites, a high-end designer kitchen, and luxurious spa bathrooms.

Spacious Apartment in Gaslamp, Sleeps 5 w/ Parking
Please Read Entire Listing Before Booking Noise Warning Come stay at our mid century modern apartment inside of a stylish Historic building. Located in the heart of Gaslamp Quarter. This 800 sqft apartment is perfect for a couples vacation, friends night out, or traveling business people. The Gaslamp action is right downstairs. The loft is surrounded by restaurants, bars, nightclubs, and coffee shops. Within walking distance to the Convention Center, Petco Park. Sleeps up to 5.

Waterfront Loft | 1BR | Little Italy | Downtown
The local neighborhood is highly walk-able and perched along the San Diego Bay in Little Italy. Little Italy is the most vibrant neighborhood in downtown San Diego with a main street that abounds with restaurants, boutiques, craft beer, and wine bars all at your doorstep. This is a very urban location which brings a lot of urban noise. The unit sits adjacent the train and trolley line in the urban core. No parking provided, Ideal for guests without a car.

Downtown San Diego Loft | Best Walkable Location
Stay steps from Petco Park in a thoughtfully designed two-story loft in the heart of downtown San Diego. Designed by award-winning architect Jonathan Segal, this modern space features high ceilings, a calm open layout, and a private balcony with city views. Enjoy a queen bed upstairs and a sofa bed in the living room, plus a full kitchen, washer/dryer, and easy self check-in. A more spacious, private, and relaxed alternative to typical downtown hotel stays.

At Mine | Spacious Suite in the Gaslamp Quarter
This meticulously renovated historical hotel suite, designed by Pininfarina, is located in Downtown San Diego’s vibrant Gaslamp Quarter, surrounded by restaurants and nightlife. It offers private, spacious accommodations for both business and leisure travelers, featuring a king bed, smart TV, central AC, and mini-fridge. Please note: an adjoining bar operates until midnight, and some noise is expected.

Top Floor Views of Ocean, Bay, City & Petco Park
Experience San Diego from a 32-story penthouse with floor-to-ceiling views of Petco Park, the bay, ocean, and skyline. Walk to Gaslamp, the Convention Center, and Seaport Village. Enjoy rooftop lounges, pools, gym, and resort-style amenities. Limited time: 20-40% off many dates available for booking now. Perfect for a weekend getaway, business trip, or special occasion in the heart of downtown.
Popular amenities for Downtown San Diego holiday rentals
Other great holiday rentals in Downtown San Diego

Peaceful Jungle Retreat In The Heart of San Diego

Waterfront Little Italy Loft

Artifact Inn - Escape in Vibrant Studio Top Spot!

Bright 2BR | Views &Walkability

Stunning Views & 1 min to Petco Park 1BD Apartment

Luxury High-Rise | Downtown SD

Hip Industrial Loft in San Diego

Kasa Little Italy | Studio, Rooftop Pool & Lux Gym
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | $228 NZD | $242 NZD | $259 NZD | $228 NZD | $242 NZD | $240 NZD | $288 NZD | $245 NZD | $231 NZD | $238 NZD | $237 NZD | $240 NZD |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Destinations to explore
- Rentals with a home theatre Downtown San Diego
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- Smoking-friendly rentals Downtown San Diego
- Fitness-friendly rentals Downtown San Diego
- Townhouse rentals Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Rentals with a fireplace Downtown San Diego
- Boutique hotels Downtown San Diego
- Resort rentals Downtown San Diego
- Rentals with outdoor seating Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with breakfast Downtown San Diego
- House rentals Downtown San Diego
- Rentals with pools Downtown San Diego
- Hostel rentals Downtown San Diego
- Family-friendly rentals Downtown San Diego
- Rentals with an EV charger Downtown San Diego
- Rentals with a washing machine and dryer Downtown San Diego
- Waterfront rentals Downtown San Diego
- Hotel rooms Downtown San Diego
- Rentals with a patio Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Apartment rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Condo rentals Downtown San Diego
- SeaWorld San Diego
- Rosarito Beach
- Coronado Beach
- University of California-San Diego
- LEGOLAND California
- San Diego Zoo
- San Diego Zoo Safari Park
- Petco Park
- San Diego Convention Center E Ent
- Pacific Beach
- Balboa Park
- Tijuana Beach
- San Diego State University
- Torrey Pines State Beach
- Oceanside City Beach
- Mission Beach
- Ocean Front Walk
- Moonlight State Beach
- Las Olas Resort & Spa
- La Misión Beach
- Belmont Park
- Sesame Place San Diego
- Liberty Station
- South Mission Beach, San Diego





