House holiday rentals in Eno River

Mid-Century Gem • Creekside • King Beds • Near UNC

This curated 3BR/2BA mid-century modern Chapel Hill home blends comfort, style, and nature in perfect harmony. Designed by renowned local architect JP Goforth, the home sits on a wooded acre with a private creek and features king beds in every room, Sonos audio, and fiber WiFi. Relax on the deck, fire up the grill, or unwind inside surrounded by stunning hand-selected art and furnishings. Minutes from UNC, Whole Foods, and Eastwood Lake, it’s a true retreat for anyone craving serenity and style.

Value · Family · Accuracy

Modernist Masterpiece: 'Simply the Best'

Welcome to Hazel Modernist 6 - designed and built by Alicia Hylton-Daniel, with her "sister," Modernist 5, next door. Centrally located downtown, this gorgeous escape is truly livable. Fully equipped chefs kitchen opens into the large living & dining space, with Frame TV and fireplace. 3BR & private back deck offer plenty of space together or alone. Each home by Alicia is infused with creative and new design concepts. This glamorous home celebrates the essence of Tina Turner, Simply the Best.

Location · Family · Hospitality

Artist-Designed Cabin Near Duke & Downtown

Relax and recharge in a modern, artist-designed passive solar home tucked into the woods just minutes from downtown Durham and Duke University. This cabin-style retreat blends nature, comfort, and convenience — ideal for weekend getaways, visiting Duke, or extended stays. Inside you’ll find original artwork, abundant natural light, and a professionally equipped kitchen. Outside, enjoy birdsong and mature trees while staying close to Durham’s restaurants, coffee shops, breweries, and shopping.

Family · Value · View

Desirable Family Neighborhood, Near Duke/Hospital

This beautifully renovated home offers a warm and inviting atmosphere, just minutes from a golf course, Downtown Durham, parks, shopping, and I-85. Enjoy scenic walking trails just down the block, museums, and restaurants. The home is also conveniently located near major hospitals, including Duke and VA Hospitals, as well as rehabilitation centers. Perfect for 2-4 adults or a small family, with a fully fenced backyard. Pet-Friendly: Pre-approved dogs (up to 2) allowed with a $125 charge.

Location · Family · Getting around

Stylish/historic home, walk to Duke & 9th Street!

Get comfortable, have a drink & enjoy the porch! This renovated home away from home is in popular Old West Durham neighborhood! Duke East campus is a leisurely 15 minute walk or 2 minute drive. You’ll be one block from 9th Street, so great food and shopping are just around the corner. We’re centrally located to anything that brings you to the area: 2 miles to Duke Hospital, DPAC, Downtown Durham, and the Museum of Life and Science, 12 miles to Chapel Hill, and 27 miles to Downtown Raleigh.

Family · Value · Bathroom

Near Duke, Southpoint, UNC

Discover the perfect retreat in South Durham, NC! Our tranquil Airbnb offers an idyllic escape with a prime central location that guarantees a memorable stay. Start your morning on the inviting screen porch, where you can relish a cup of coffee and take in the view of the flower garden before headed out to enjoy some of the Triangle's finest attractions. Convenience is at your fingertips, as our Airbnb is just minutes away from RTP, RDU airport, Downtown Durham, DUKE, UNC, and the DPAC.

Value · Family · Parking

Comfy Boho 2BR - Near UNC & Duke, Walk to Wegmans

Ideally located near UNC and Duke, this fully renovated 2BR home sits on the Chapel Hill–Durham border and is just a short walk to Wegmans. Perfect for hospital visitors, academics, and longer stays, the home offers fast Wi-Fi, a dedicated workspace, plenty of free parking, and a comfortable setting in a lively neighborhood. We’ve named this adorable stay Maison de Mariposa, in honor of the butterfly - a symbol of hope and love. Come relax and enjoy our lovely, comfortable retreat.

Value · Family · Check-in

Luxurious Modernist Tree House

Stunning, private, and truly one-of-a-kind—this unique home is perfect for a vacation, staycation, special occasion, or simply celebrating everyday life. Designed by renowned modernist architect Frank Harmon. The 2,128-square-foot residence sits on 1.3 acres and was crafted with meticulous attention to detail. Inside, you’ll feel nestled among the treetops while remaining conveniently close to restaurants, shopping, downtown Raleigh, WakeMed, UNC, Duke, and Research Triangle Park.

Location · Value · Air conditioning

Walk to Downtown Hillsborough • Dog Friendly

More than just a vacation rental, this is a home we love and are happy to share. Tucked into a quiet, walkable neighborhood near historic downtown Hillsborough, you can walk to restaurants, coffee shops, galleries, Gold Park, the Riverwalk, and the Eno River, then come home to relax on the porch or in the fenced backyard. Thoughtfully stocked for comfortable everyday living, it’s ideal for weekend getaways, weddings, family visits, and trips to Duke or UNC. Dogs are welcome, too.

Value · Family · Cleanliness

Retreat to Historic Home in a Private Arboretum

Unwind and renew your spirit in our updated 5 bedroom (sleeps 9) historic house (circa 1830's) in the heart of the largest arboretum of its kind in the USA. Explore our exotic 206 acre property sheltering 4000 different North American and international tree species. Hike through old growth forest past historic outbuildings and watch the sun sparkle on our ponds. We are family and pet friendly, 25 minutes to Duke University, 17 minutes to UNC Chapel Hill.

Value · Location · Access

The Angier House | Modern Smart Home | 4Car Garage

Urban-modern near downtown living. Newly built and furnished 4 bedroom, 3.5 bath and features 2 owner suites, on first level and second level of the home. The house has a strong presence with minimal styling to create for a nice vibe and good times. Meticulous attention to detail everywhere you look from the chef-inspired kitchen to the two spacious en suite bathrooms.

Family · Location · Amenities

Cheerful 2-bedroom home in quiet cul de sac

Bright and lovely duplex nestled away in a quiet cul de sac. Duke and downtown are reachable in minutes, and there's a Harris Teether within walking distance. Enjoy the outdoor space, or relax in the living room sorrounded by art and music. Accessibility: The sidewalk and entryway are not wheelchair accessible, guests using wheelchairs may need assistance.

Value · Family · Hospitality